Results 41 to 50 of about 45,533 (284)
Parameters for Irreversible Inactivation of Monoamine Oxidase
Molecules, 2020 The irreversible inhibitors of monoamine oxidases (MAO) slow neurotransmitter metabolism in depression and neurodegenerative diseases. After oxidation by MAO, hydrazines, cyclopropylamines and propargylamines form a covalent adduct with the flavin ...
Rona R. Ramsay +8 more
doaj +1 more source
An amine oxidase gene from mud crab, Scylla paramamosain, regulates the neurotransmitters serotonin and dopamine in vitro. [PDF]
PLoS ONE, 2018 Amine oxidase, which participates in the metabolic processing of biogenic amines, is widely found in organisms, including higher organisms and various microorganisms.
Junguo Liu +8 more
doaj +1 more source
CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao +7 more
wiley +1 more source
MONOAMINE OXIDASE A (MAOA), CHILDHOOD TRAUMA, ALCOHOLISM AND AGGRESSION [PDF]
, 2008 Women who have experienced childhood sexual abuse (CSA) have an increased risk of alcoholism and antisocial personality disorder (ASPD). Among males, a functional polymorphism (MAOA-LPR, monoamine oxidase A linked polymorphic region) in the promoter ...
DUCCI, FRANCESCA
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[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich +19 more
wiley +1 more source
Calcium ions alter monoamine oxidase A activity [PDF]
, 2013 S. Armstrong graduated from the University of St Andrews in 2011Activation of the flavoprotein monoamine oxidase A (MAO A) by calcium ions has been reported in isolated mitochondria, in cell lines, and in vivo. Enhanced MAO A activity has been associated
Ramsay, Rona R., Armstrong, Stephanie
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Platelet monoamine oxidase activity in diabetics.
Acta Médica Portuguesa, 1980 Platelet monoamine oxidase (MAO) activity was determined, using benzylamine as substract. Results are expressed as nM benzaldehyde/mg protein hour, at 37”. A total of 79 diabetics (40 M and 39 F) ranging in age from 3 to 70 years was studied.
Maria Azevedo +3 more
doaj +1 more source
Questions in the Chemical Enzymology of MAO
Chemistry, 2021 We have structure, a wealth of kinetic data, thousands of chemical ligands and clinical information for the effects of a range of drugs on monoamine oxidase activity in vivo.
Rona R. Ramsay, Alen Albreht
doaj +1 more source
Advanced Healthcare Materials, EarlyView.Mitochondria‐targeted nanotherapies emerge as a promising strategy for combating aging‐associated neurodegenerative disorders (NDs) by restoring mitochondrial function, reducing oxidative stress, and improving neuronal survival. Recent advances in nanotechnology, therapeutic delivery, and translational research are highlighted, providing insights into ...
Dnyandev G. Gadhave +8 more
wiley +1 more source
Monoamine oxidase in neuronal cell death [PDF]
, 2008 Monoamine oxidase (MAO) is an oxidative enzyme that deaminates a variety of amine substrates, including the neurotransmitter dopamine. The enzymatic reaction requires molecular oxygen and produces hydrogen peroxide as a by-product.
Fitzgerald, J
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