Results 41 to 50 of about 186,317 (243)
Behavioral and Biochemical Effects of Monosodium Glutamate on Weaned Male Rats [PDF]
The present study investigates the effect of long term treatment (0.06,0.3 and 0.6g/kg b. wt., orally) with monosodium glutamate (MSG) on open field test and some biochemical parameters such as cortisol, serotonin (5-HT) and monoamine oxidase activity ...
Mervat Kamel +3 more
doaj +1 more source
Questions in the Chemical Enzymology of MAO
We have structure, a wealth of kinetic data, thousands of chemical ligands and clinical information for the effects of a range of drugs on monoamine oxidase activity in vivo.
Rona R. Ramsay, Alen Albreht
doaj +1 more source
Ketogenic diet for infantile epileptic spasms
Abstract Approximately half of all cases of Infantile Epileptic Spasms Syndrome (IESS) do not respond to vigabatrin and hormonal therapies. There is no clear consensus as to the second‐line therapy for IESS. Ketogenic diet (KD) has emerged as an effective treatment for certain drug‐resistant epilepsies and in many cases of IESS.
Morris H. Scantlebury +3 more
wiley +1 more source
Isatin: identity with the purified endogenous monoamine oxidase inhibitor tribulin
Purified tribulin, an endogenous monoamine oxidase (MAO) inhibitor, has been identified by direct probe insertion mass spectrometry as the indole-2,3-dione, isatin.
Watkins, P.J. +5 more
core +1 more source
Baroreflex Failure After Surgical Resection of Bilateral Carotid Body Tumors: A Systematic Review
ABSTRACT Objective Surgery remains the definitive treatment for carotid body tumors (CBTs); however, concern persists regarding the risk of baroreflex failure (BRF) following bilateral CBT resection. The true incidence and long‐term clinical course of BRF remain poorly defined. We performed a systematic review to examine the risk and clinical course of
Alex Z. Graboyes +8 more
wiley +1 more source
Monoamine oxidase inhibitions are considered as important targets for the treatment of depression, anxiety, and neurodegenerative disorders, including Alzheimer’s and Parkinson’s diseases.
Priyanka Dhiman +4 more
doaj +1 more source
Long-term low-dose oxytetracycline potentially leads to neurobehavioural changes
Trace levels of oxytetracycline (OTC)—a veterinary antibiotic and feed additive—are widespread in the environment. Studies revealed that OTC potentially impairs thyroid function, which may affect neurobehaviour; however, the impact of exposure to ...
Yushu Qiu +8 more
doaj +1 more source
Abstract Background There is a lack of treatments for non‐motor symptoms (NMS) in Parkinson's disease (PD). Objective To assess the safety and effectiveness of an oral Cannabis sativa L. extract on pain and other NMS of PD. Methods This phase II, randomized, placebo‐controlled trial evaluated a formulation containing cannabidiol (CBD; 96 mg/ml) and Δ9 ...
Gabriel T. Kubota +14 more
wiley +1 more source
Design and Synthesis of Novel and Potent Monoamine Oxidase Inhibitors
Reversible and selective monoamine oxidase-A inhibitors (RIMA's) like moclobemide (Aurorix®) have rehabilitated the use of MAO inhibitors as drugs of choice in depression.
Quirico Branca +4 more
doaj +2 more sources
Apathy in Lewy Body Disorders: A Position Paper
Abstract Apathy is one of the most prevalent and disabling non‐motor symptoms in Parkinson's disease (PD) and dementia with Lewy bodies (DLB), collectively referred to as Lewy body disorders (LBDs). It is associated with reduced quality of life, accelerated cognitive decline, increased caregiver burden, and poorer functional outcomes, yet remains ...
Jaime Kulisevsky +12 more
wiley +1 more source

