Results 71 to 80 of about 36,956 (236)

Do Genetics Shape Mental Health Trajectories Around Partnership Transitions?

open access: yesJournal of Marriage and Family, EarlyView.
ABSTRACT Objective This study focuses on the extent to which genetic risk for mental disorders contributes to observed mental health problems before and after partnership transitions. Background Partnership formation and dissolution are linked to short‐term changes in mental health, with outcomes varying by gender, socioeconomic position, and other ...
Philipp Dierker   +5 more
wiley   +1 more source

BSAVA Petsavers Article: Validation of an ELISA assay for measurement of the metabolite of serotonin, 5‐hydroxyindole acetic acid (5‐HIAA), in canine urine

open access: yesJournal of Small Animal Practice, EarlyView.
Objectives Serotonin (5‐hydroxytryptophan), implicated in a number of canine diseases, has a very short half‐life in the serum. Urine concentration of its breakdown product 5‐hydroxyindole acetic acid after an 8 hour fast is a more reliable measure of circulating serotonin in humans.
D. Castillo   +3 more
wiley   +1 more source

Neurogenic Stuttering and Lateralized Motor Deficits Induced by Tranylcypromine

open access: yesBehavioural Neurology, 1994
A case of neurogenic stuttering induced by the monoamine oxidase inhibitor tranylcypromine is described. The association of neurogenic stuttering with acquired lateralized motor deficits in the patient described is discussed with reference to current ...
J. D. Duffy
doaj   +1 more source

Saccharomyces cerevisiae Yeast‐Based Supplement and Breast Milk Supply: A Randomised Placebo‐Controlled Trial

open access: yesMaternal &Child Nutrition, EarlyView.
Maternal brewer's yeast supplementation did not change the milk oligosaccharide (HMO) concentration, but more mothers felt their milk supply was increased, and fewer reported formula use by 6 months postpartum compared to those taking the placebo. This suggests the supplement may support breastfeeding, warranting further investigation in larger trials.
Lili Jia, Louise Brough, Janet L. Weber
wiley   +1 more source

Mechanism-based tuning of insect 3,4-dihydroxyphenylacetaldehyde synthase for synthetic bioproduction of benzylisoquinoline alkaloids

open access: yesNature Communications, 2019
Bioproduction of tetrahydropapaveroline (THP) is limited by the specificity of monoamine oxidase (MAO). Here, the authors identify an insect 3,4-dihydroxyphenylacetaldehyde synthase (DHPAAS) that can bypass MAO for direct aldehyde production and ...
Christopher J. Vavricka   +14 more
doaj   +1 more source

Synthesis and Biological Evaluation of New Thiosemicarbazone Derivative Schiff Bases as Monoamine Oxidase Inhibitory Agents

open access: yesMolecules, 2017
Twenty-six novel thiosemicarbazone derivative B1–B26 were synthesized via condensation reactions between the corresponding thiosemicarbazides and aldehydes.
Betül Kaya Çavuşoğlu   +7 more
doaj   +1 more source

Innovations in Obesity Treatment: Beyond Adipose Tissue Dysfunction

open access: yesObesity Reviews, EarlyView.
Obesity drives chronic inflammation, insulin resistance, type 2 diabetes, and cancer development through adipocyte dysfunction. Addressing this multisystemic disorder requires integrated strategies beyond diet and exercise, such as thermogenesis activation via menthol or capsinoids and appetite control through GLP‐1/GIP agonists and neuromodulation to ...
Jesica Martínez‐Godfrey   +7 more
wiley   +1 more source

Drug‐Induced Sialolithiasis—A Big‐Data Retrospective Study

open access: yesOral Diseases, EarlyView.
ABSTRACT Background Sialolithiasis pathophysiology is multifactorial, with systemic medications often hypothesised as a key contributor, particularly in older adults (Drug‐Induced Sialolithiasis). However, robust evidence supporting this theory is limited.
Gal Avishai   +5 more
wiley   +1 more source

Rhizobacteria‐Induced Systemic Priming Against Fungal Pathogens Involves Hydroxycinnamic Acid Amides

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT The rhizosphere, a narrow region of soil surrounding roots, contains diverse microorganisms with a composition that is distinct from the surrounding soil. Some rhizosphere bacteria can trigger a heightened state of immunity in the whole plant, termed Induced Systemic Resistance (ISR).
Mackenzie Eli William Loranger   +5 more
wiley   +1 more source

3-Coumaranone derivatives as inhibitors of monoamine oxidase

open access: yesDrug Design, Development and Therapy, 2015
Adriaan S Van Dyk,1,2 Jacobus P Petzer,1,2 Anél Petzer,1 Lesetja J Legoabe1 1Centre of Excellence for Pharmaceutical Sciences, 2Pharmaceutical Chemistry, School of Pharmacy, North-West University, Potchefstroom, South Africa Abstract: The ...
Van Dyk AS   +3 more
doaj  

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