Drugs Affecting 5-HT Systems [PDF]
, 2013 Seminar transcriptIt was in the very early hours of a February morning in 1977 that I first looked down the microscope and saw yellow fluorescence, characteristic of 5-hydroxytryptamine (5-HT) in frozen sections of Octopus brain. After struggling for two
Overy, C, Tansey, EM
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Potential antidepressant effects of scutellaria baicalensis, hericium erinaceus and rhodiola rosea [PDF]
, 2020 Recent studies focused on the pharmacology and feasibility of herbal compounds as a potential strategy to target a variety of human diseases ranging from metabolic to brain disorders. Accordingly, bioactive ingredients which are found within a variety of
Biagioni, F +5 more
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Monoamine oxidase A upregulated by chronic intermittent hypoxia activates indoleamine 2,3-dioxygenase and neurodegeneration [PDF]
, 2017 published_or_final_versio
Fung, ML +4 more
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3-Coumaranone derivatives as inhibitors of monoamine oxidase
Drug Design, Development and Therapy, 2015 Adriaan S Van Dyk,1,2 Jacobus P Petzer,1,2 Anél Petzer,1 Lesetja J Legoabe1 1Centre of Excellence for Pharmaceutical Sciences, 2Pharmaceutical Chemistry, School of Pharmacy, North-West University, Potchefstroom, South Africa Abstract: The ...
Van Dyk AS +3 more
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Novas estratégias terapêuticas para o tratamento da depressão: uma visão da química medicinal
Química Nova, 2003 Depression is a widespread humor disturbance promoted mainly by depletion of biogenic neurotransmitter amines involved in the CNS synapses. Effective drug treatments for depression have been available for more than forty years.
Romeiro Luiz Antonio Soares +2 more
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HPLC–UV assay for the evaluation of inhibitors of plasma amine oxidase using crude bovine plasma
Journal of Enzyme Inhibition and Medicinal Chemistry, 2019 Recently, we have described a method for evaluation of plasma amine oxidase (PAO) inhibitors, which monitors the formation of 6-(5-phenyl-2H-tetrazol-2-yl)hexanal from the corresponding amine substrate by HPLC with UV-detection using purified bovine PAO.
Kira Mergemeier +2 more
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Multi-targeting aurones with monoamine oxidase and amyloid-beta inhibitory activities: structure-activity relationship and translating multi-potency to neuroprotection [PDF]
, 2019 Previously, a series of aurones bearing amine and carbamate functionalities was synthesized and evaluated for their cholinesterase inhibitory activity and drug-like attributes.
Chan, Kit Lam +3 more
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Journal of Enzyme Inhibition and Medicinal Chemistry, 2020 The inhibition of monoamine oxidase B (MAO-B) could be an effective approach for the treatment of various neurological disorders. In this study, a series of 1, 4-benzodioxan-substituted chalcone derivatives were designed, synthesised and evaluated for ...
Zhuo Kong +3 more
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Patient Preference and Adherence, 2011 Bradley J RobottomDepartment of Neurology, University of Maryland School of Medicine, Baltimore, MD, USAAbstract: Parkinson's disease (PD) is the second most common neurodegenerative disease and the most treatable.
Bradley J Robottom
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MAO-A and the EEG Recognition Memory Signal in Left Parietal Cortex [PDF]
, 2014 A key part of episodic memory, or memory for the events of our lives, is recognition memory. Recognition memory is the ability to remember previously encountered stimuli.
Curran, Tim +3 more
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