Molecular Investigation of the Antitumor Effects of Monoamine Oxidase Inhibitors in Breast Cancer Cells. [PDF]
Biomed Res Int, 2023 Alkhawaldeh A, Bardaweel S.
europepmc +1 more source
Numeric modeling of fire suppression by organophosphorous inhibitors [PDF]
arXiv, 2008 Numerical calculations of the effect of organophosphorous inhibitor (CF3CH2O)3P and its mixtures with carbon dioxide on propane flames are carried out using the three dimensional Reynolds-averaged Navier-Stokes (RANS) equations in the low Mach number approximation. The k-e model of turbulence, the EDC combustion model and the weighted-sum-of-gray-gases
arxiv
In Silico Design, Extended Molecular Dynamic Simulations and Binding Energy Calculations for a New Series of Dually Acting Inhibitors against EGFR and HER2 [PDF]
arXiv, 2013 Starting from the lead structure we have identified in our previous works, we are extending our insight understanding of its potential inhibitory effect against both EGFR and HER2 receptors. Herein and using extended molecular dynamic simulations and different scoring techniques, we are providing plausible explanations for the observed inhibitory ...
arxiv
Safety comparisons among monoamine oxidase inhibitors against Parkinson's disease using FDA adverse event reporting system. [PDF]
Sci Rep, 2023 Asano H +5 more
europepmc +1 more source
L-deprenyl, A Selective MAO-B Inhibitor [PDF]
, 2011 Monoamine oxidase inhibitors (MAOIs) are now recognized as effective medications in the treatment of major depression (1). However, their clinical use has been limited by the risk of severe hypertensive reactions to oral tyramine challenge. Prevention of
Lam, MD, Raymond W.
core +1 more source
A framework for generalized group testing with inhibitors and its potential application in neuroscience [PDF]
arXiv, 2018 The main goal of group testing with inhibitors (GTI) is to efficiently identify a small number of defective items and inhibitor items in a large set of items. A test on a subset of items is positive if the subset satisfies some specific properties. Inhibitor items cancel the effects of defective items, which often make the outcome of a test containing ...
arxiv
Isatin-based benzyloxybenzene derivatives as monoamine oxidase inhibitors with neuroprotective effect targeting neurogenerative disease treatment. [PDF]
RSC Adv, 2023 Benny F +9 more
europepmc +1 more source
Design of a folding inhibitor of the HIV-1 Protease [PDF]
arXiv, 2004 Being HIV-1-PR an essential enzyme in the viral life cycle, its inhibition can control AIDS. Because the folding of single domain proteins, like HIV-1-PR is controlled by local elementary structures (LES, folding units stabilized by strongly interacting, highly conserved amino acids) which have evolved over myriads of generations to recognize and ...
arxiv
Screening of Monoamine Oxidase Inhibitors from Seeds of Nigella glandulifera Freyn et Sint. by Ligand Fishing and Their Neuroprotective Activity. [PDF]
Plants (Basel), 2023 Ayeni EA +5 more
europepmc +1 more source