Results 81 to 90 of about 43,571 (190)

Drug Repurposing for Duchenne Muscular Dystrophy: The Monoamine Oxidase B Inhibitor Safinamide Ameliorates the Pathological Phenotype in mdx Mice and in Myogenic Cultures From DMD Patients [PDF]

, 2018
Oxidative stress and mitochondrial dysfunction play a crucial role in the pathophysiology of muscular dystrophies. We previously reported that the mitochondrial enzyme monoamine oxidase (MAO) is a relevant source of reactive oxygen species (ROS) not only
Acosta, Manuel, Blaauw, Bert, Canton, Marcella, Forestan, Giada, Marabita, Manuela, Mouly, Vincent, Nogara, Leonardo, Salviati, Leonardo, Sorato, Elisa, Vitiello, Libero   +9 more
core   +7 more sources

MPTP-induced degeneration: interference with glutamatergic toxicity [PDF]

, 1994
Parkinson's disease (PD) is characterised by the progressive degeneration of nigrostriatal dopamine (DA) neurons resulting in the major symptoms of akinesia and rigidity.
Lange, Klaus W., Löschmann, P. A., Turski, L., Wachtel, H.   +3 more
core  

Molecular Investigation of the Antitumor Effects of Monoamine Oxidase Inhibitors in Breast Cancer Cells. [PDF]

Biomed Res Int, 2023
Alkhawaldeh A, Bardaweel S.
europepmc   +1 more source

Hallucinogens: mechanisms and medical complications [PDF]

, 2013
Thesis (M.A.)--Boston UniversityHallucinogens are drugs that alter consciousness by distorting primarily auditory and visual perception but they can affect any sensory system. Hallucinogens also affect judgment, orientation, memory, or emotion.
Chan, Ryan Harry Alexander
core   +1 more source

In Vitro Evaluation of Novel Furo[3,2-c]coumarins as Cholinesterases and Monoamine Oxidases Inhibitors

Molecules
Coumarin represents a privileged structural motif that is quite common in nature-derived and synthetic bioactive molecules. Some of us have recently described the straightforward preparation of complex furo[3,2-c]coumarins through a sequential double ...
Mariagrazia Rullo, Alice Benzi, Lara Bianchi, Massimo Maccagno, Guglielmo Marcantoni Taddei, Daniela Valeria Miniero, Giuseppe Felice Mangiatordi, Giovanni Lentini, Leonardo Pisani, Giovanni Petrillo, Cinzia Tavani   +10 more
doaj   +1 more source

Potentials of Curcumin as an Antidepressant

The Scientific World Journal, 2009
Major depression, a debilitating psychiatric disorder, is predicted to be the second most prevalent human illness by the year 2020. Various antidepressants, ranging from monoamine oxidase inhibitors to recently developed dual reuptake inhibitors, are ...
S.K. Kulkarni, Ashish Dhir, Kiran Kumar Akula   +2 more
doaj   +1 more source

Getting the balance right: Established and emerging therapies for major depressive disorders

Neuropsychiatric Disease and Treatment, 2010
Bojana Perovic, Marija Jovanovic, Branislava Miljkovic, Sandra VezmarDepartment of Pharmacokinetics, Faculty of Pharmacy, University of Belgrade, SerbiaAbstract: Major depressive disorder (MDD) is a common and serious illness of our times, associated ...
Bojana Perovic, Marija Jovanovic, Branislava Miljkovic, et al   +3 more
doaj  

Safety comparisons among monoamine oxidase inhibitors against Parkinson's disease using FDA adverse event reporting system. [PDF]

Sci Rep, 2023
Asano H, Tian YS, Hatabu A, Takagi T, Ueda M, Ikeda K.   +5 more
europepmc   +1 more source

Clinically Relevant Drug Interactions with Monoamine Oxidase Inhibitors. [PDF]

Health Psychol Res, 2022
Edinoff AN, Swinford CR, Odisho AS, Burroughs CR, Stark CW, Raslan WA, Cornett EM, Kaye AM, Kaye AD.   +8 more
europepmc   +1 more source

Exploration of the Detailed Structure-Activity Relationships of Isatin and Their Isomers As Monoamine Oxidase Inhibitors. [PDF]

ACS Omega, 2022
Kumar S, Nair AS, Abdelgawad MA, Mathew B.   +3 more
europepmc   +1 more source