Results 141 to 150 of about 9,063 (256)
Risk of gastrointestinal bleeding by specific SSRIs and SNRIs: A systematic review and meta‐analysis
British Journal of Clinical Pharmacology, Volume 92, Issue 3, Page 793-808, March 2026.Aim The purpose of this study is to estimate the risk of gastrointestinal bleeding (GIB) by selective serotonin reuptake inhibitors (SSRIs) and serotonin–norepinephrine reuptake inhibitors (SNRIs) individual agents. Methods A systematic review was conducted for each unique antidepressant (i.e.
Ainhoa Gomez‐Lumbreras +8 more
wiley +1 more source
Inhibition of Human Monoamine Oxidases A and B by Specialized Metabolites Present in Fresh Common Fruits and Vegetables. [PDF]
Plants (Basel), 2022 Marzo CM +5 more
europepmc +1 more source
Chemistry &Biodiversity, Volume 23, Issue 3, March 2026.ABSTRACT This study provides an analysis of the endemic plant Mattiastrum paphlagonicum Bornm.(Synonym Paracaryum paphlagonicum (Bornm.) R.R. Mill), focusing on enzyme activity, secondary metabolite content, antioxidant capacity (DPPH, ABTS, and FRAP), as well as phenolic and flavonoid levels, all within the context of a hydroethanolic extract prepared
Ayşenur Kayabaş Avşar +4 more
wiley +1 more source
Clinical Pharmacology in Drug Development, Volume 15, Issue 3, March 2026.Abstract This single‐center, randomized, open‐label bioequivalence program compared two fixed‐dose combination (FDC) tablets containing ibuprofen (200 mg) and phenylephrine hydrochloride (10 mg) from different manufacturers in healthy Chinese adults under fasting and fed conditions. A three‐period, partially replicated crossover design was used for the
Menghan Ye +8 more
wiley +1 more source
Coumarin-Based Dual Inhibitors of Human Carbonic Anhydrases and Monoamine Oxidases Featuring Amino Acyl and (Pseudo)-Dipeptidyl Appendages: In Vitro and Computational Studies. [PDF]
Molecules, 2022 Agamennone M +7 more
europepmc +1 more source
Clinical Pharmacology in Drug Development, Volume 15, Issue 3, March 2026.Abstract Daily oral cyclobenzaprine hydrochloride (HCl) has provided transient benefits in fibromyalgia, a chronic pain condition. To improve this effect, we evaluated sublingual formulations designed to drive transmucosal absorption. Two open‐label studies evaluated the pharmacokinetics (PK), tolerability, and relative bioavailability of sublingual ...
Bruce L Daugherty +4 more
wiley +1 more source
Molecular Modeling and Experimental Evaluation of Non-Chiral Components of Bergamot Essential Oil with Inhibitory Activity against Human Monoamine Oxidases. [PDF]
Molecules, 2022 Catalano R +6 more
europepmc +1 more source
L-deprenyl, A Selective MAO-B Inhibitor [PDF]
, 2011 Monoamine oxidase inhibitors (MAOIs) are now recognized as effective medications in the treatment of major depression (1). However, their clinical use has been limited by the risk of severe hypertensive reactions to oral tyramine challenge. Prevention of
Lam, MD, Raymond W.
core +1 more source
Food Science &Nutrition, Volume 14, Issue 3, March 2026.Exercise and dietary polyphenols enhance hippocampal plasticity and cognitive function via complementary molecular mechanisms. Central pathways include BDNF signaling, inflammation control, and mitochondrial regulation. Although synergy is mainly supported by preclinical data, lifestyle‐based strategies show promise for brain health maintenance ...
Zhenyi Zhao, Sima‐sadat Sabihi
wiley +1 more source
Endometrial Stromal Cell Senescence: A Non‐Negligible Factor in Recurrent Pregnancy Loss
iMetaMed, Volume 2, Issue 1, March 2026.As populations age, links between female reproductive aging and infertility are increasingly evident. Cellular senescence, characterized by near‐irreversible cell‐cycle arrest and accumulation of damage, can impair tissue function. In the endometrium, aberrant senescence of endometrial stromal cells (EnSCs) may compromise receptivity, hinder embryo ...
Shuang Wu +6 more
wiley +1 more source