Results 11 to 20 of about 9,063 (256)
Monoamine Oxidases (MAOs) as Privileged Molecular Targets in Neuroscience: Research Literature Analysis [PDF]
Frontiers in Molecular Neuroscience, 2019 Background: Monoamine oxidases (MAOs) were discovered nearly a century ago. This article aims to analyze the research literature landscape associated with MAOs as privileged class of neuronal enzymes (neuroenzymes) with key functions in the processes of ...
Andy Wai Kan Yeung +4 more
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Central Effects of 3-Iodothyronamine Reveal a Novel Role for Mitochondrial Monoamine Oxidases [PDF]
Frontiers in Endocrinology, 2018 3-Iodothyronamine (T1AM) is the last iodinated thyronamine generated from thyroid hormone alternative metabolism found circulating in rodents and in humans. So far, the physiopathological meaning of T1AM tissue levels is unknown. Much is instead known on
Annunziatina Laurino +2 more
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M30 Antagonizes Indoleamine 2,3-Dioxygenase Activation and Neurodegeneration Induced by Corticosterone in the Hippocampus. [PDF]
PLoS ONE, 2016 Monoamine oxidases (MAO), downstream targets of glucocorticoid, maintain the turnover and homeostasis of monoamine neurotransmitters; yet, its pathophysiological role in monoamine deficiency, oxidative stress and neuroinflammation remains controversial ...
Chun-Sing Lam +4 more
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Monoamine oxidases in development. [PDF]
Cell Mol Life Sci, 2013 Monoamine oxidases (MAOs) are flavoproteins of the outer mitochondrial membrane that catalyze the oxidative deamination of biogenic and xenobiotic amines. In mammals there are two isoforms (MAO-A and MAO-B) that can be distinguished on the basis of their substrate specificity and their sensitivity towards specific inhibitors.
Wang CC +4 more
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Correction: From warrior genes to translational solutions: novel insights into monoamine oxidases (MAOs) and aggression [PDF]
Translational Psychiatry, 2021 Alexios-Fotios A. Mentis +3 more
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Journal of Pharmacological Sciences, 2021 The orexinergic system plays a significant role in regulating proper sleep/wake maintenance. Dual orexin receptor antagonist (DORA) is widely prescribed for insomnia symptoms. The antagonist acts on orexin 1 and 2 receptors located in certain brain areas,
Shunpei Moriya +5 more
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Questions in the Chemical Enzymology of MAO
Chemistry, 2021 We have structure, a wealth of kinetic data, thousands of chemical ligands and clinical information for the effects of a range of drugs on monoamine oxidase activity in vivo.
Rona R. Ramsay, Alen Albreht
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Frontiers in Pharmacology, 2021 Mucosal epithelial cell integrity is an important component of innate immunity and it protects the host from an environment rich in microorganisms. Virulence factors from Gram-negative bacteria [e.g.
Edward E. Putnins +2 more
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Monoamine oxidase inhibitors [PDF]
Anaesthesia, 1964 Publisher Summary This chapter describes the various classes of chemical compounds, which have an inhibitory action on monoamine oxidase (MAO). The chapter discusses the current theories of the function of monoamine oxidase and the possible mechanism by which the MAO inhibitors (MAOI) react with MAO.
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Antioxidants, 2023 Oxidative catabolism of monoamine neurotransmitters by monoamine oxidases (MAOs) produces reactive oxygen species (ROS), which contributes to neuronal cells’ death and also lowers monoamine neurotransmitter levels.
Ahmed H. E. Hassan +14 more
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