Results 121 to 130 of about 10,352 (144)
Some of the next articles are maybe not open access.
American Journal of Physiology-Gastrointestinal and Liver Physiology, 2005
Butyrate, a short-chain fatty acid, is the major energy fuel for the colonocytes. We have previously reported that monocarboxylate transporter isoform 1 (MCT1) mediates uptake of butyrate by human colonic Caco-2 cells. To better understand the mechanisms of MCT1 expression and regulation in the human intestine, we examined the activity and regulation ...
Christos, Hadjiagapiou +6 more
openaire +2 more sources
Butyrate, a short-chain fatty acid, is the major energy fuel for the colonocytes. We have previously reported that monocarboxylate transporter isoform 1 (MCT1) mediates uptake of butyrate by human colonic Caco-2 cells. To better understand the mechanisms of MCT1 expression and regulation in the human intestine, we examined the activity and regulation ...
Christos, Hadjiagapiou +6 more
openaire +2 more sources
ASSAY and Drug Development Technologies, 2019
Solute carrier proteins (SLCs) are a superfamily of transmembrane transporters that control essential physiological functions such as nutrient uptake, ion transport, and cellular waste elimination. Although many SLCs are associated with various disease states and are considered "druggable," they remain underexplored as a drug target class.
T Liz, Bailey +2 more
openaire +2 more sources
Solute carrier proteins (SLCs) are a superfamily of transmembrane transporters that control essential physiological functions such as nutrient uptake, ion transport, and cellular waste elimination. Although many SLCs are associated with various disease states and are considered "druggable," they remain underexplored as a drug target class.
T Liz, Bailey +2 more
openaire +2 more sources
Clinical and Experimental Pharmacology and Physiology, 2005
SUMMARY1. The present study was designed to examine the role of calcineurin in muscle metabolic components by the administration of the specific calcineurin inhibitor cyclosporine A (CsA) to rats.2. Male Wistar rats were divided into either a CsA‐treated group (CT) or a vehicle‐treated group (VT).
Masataka, Suwa +2 more
openaire +2 more sources
SUMMARY1. The present study was designed to examine the role of calcineurin in muscle metabolic components by the administration of the specific calcineurin inhibitor cyclosporine A (CsA) to rats.2. Male Wistar rats were divided into either a CsA‐treated group (CT) or a vehicle‐treated group (VT).
Masataka, Suwa +2 more
openaire +2 more sources
Structural basis of human monocarboxylate transporter 1 inhibition by anti-cancer drug candidates
Cell, 2021Nan Wang, Chuangye Yan, Shuo Zhang
exaly
Mammalian monocarboxylate transporter 7 (MCT7/Slc16a6) is a novel facilitative taurine transporter
Journal of Biological Chemistry, 2022Katsuhisa Inoue
exaly
Monocarboxylate transport in erythrocytes
Journal of Membrane Biology, 1982B Deuticke, Deuticke B
exaly