Results 201 to 210 of about 198,185 (239)

Asthma: onset at young, persist when grow up. [PDF]

Transl Pediatr
Siu KK, Lin LY, Kwok WC.
europepmc   +1 more source

Development of an Active Chimeric IL13Rα2 ADC for Diffuse Intrinsic Pontine Glioma. [PDF]

Immunotargets Ther
Lian X, Allanson VJ, Rasmussen SV, Chauhan S, Tan GK, Morrow P, Hanson K, Lian EB, Haight AR, Hoshino T, Liu X, Berlow NE, Keller C, Lian Y.   +13 more
europepmc   +1 more source

Chicken interleukin-26: characterization and antigen capture enzyme-linked immunosorbent assay. [PDF]

Poult Sci
Nam H, Lee Y, Park M, Lillehoj HS.
europepmc   +1 more source

Macrophage-mimetic photothermal nanotherapeutics regulate mitochondrial homeostasis and inflammatory cascades in lung ischemia-reperfusion injury. [PDF]

Cell Rep Med
Yuan H, Zeng B, Shen P, Deng J, Chen Y, Huang M, Wu W, Xu X, Zhang X, Liu X, Zhang X, Fan Z, He J.   +12 more
europepmc   +1 more source

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Anti-IL-6 receptor monoclonal antibody as a new treatment of endometriosis

Immunologic Research, 2020
Many pro-inflammatory cytokines especially tumor necrotic factor alpha (TNFα), interleukin (IL)-1β, and IL-6 have crucial role in the pathogenesis of endometriosis. In this study, we investigated the immune-modulatory role of humanized anti-IL-6 receptor monoclonal antibodies in the treatment of endometriosis.
Ahmed A. El-Zayadi, Sara A. Mohamed, Mohammad Arafa, Shereen M. Mohammed, Abdelhady Zayed, Mohamed S. Abdelhafez, Ahmed M. Badawy   +6 more
openaire   +2 more sources

Human recombinant dimeric IL-6 binds to its receptor as detected by anti-IL-6 monoclonal antibodies

Molecular Immunology, 1991
Three different epitopes of the human IL-6 (IL-6) molecule were recognized by the mAb B-E4 (IgG2b), B-E8 (IgG1) and B-F6 (IgG1). The affinities of these three mAb for IL-6 differ little in several assays but if ranked by affinity they fall into the following order B-E8 greater than B-E4 greater than B-F6.
J, Wijdenes, C, Clement, B, Klein, B, Morel-Fourrier, N, Vita, P, Ferrara, A, Peters   +6 more
openaire   +2 more sources

Analysis of interleukin 6 (IL-6)/IL-6 receptor system using monoclonal anti-IL-6 antibodies

Molecular Immunology, 1991
To investigate the IL-6/IL-6 receptor system, we obtained five murine monoclonal antibodies against human IL-6, which neutralize its biological activity. We classified them into two groups (Type I mAb and Type II mAb) according to the epitopes they recognized. These two types of antibodies showed no difference in the manner in which they neutralized IL-
T, Shimamura, S, Taki, H, Honda, M, Yokota, S, Ito, Y, Takahara   +5 more
openaire   +2 more sources

Anti-IL-6 receptor monoclonal antibody inhibits leukocyte recruitment and promotes T-cell apoptosis in a murine model of Crohn’s disease

Journal of Gastroenterology, 2002
To assess the contribution of IL-6 signaling to the physiopathology of Crohn's disease, we introduced anti-IL-6 receptor monoclonal antibody to a murine colitis model.Colitis was induced in C.B-17-scid mice to which were transferred CD45RBhigh CD4+ T cells from Balb/c mice.
Hiroaki, Ito, Tomonori, Hirotani, Mitsunari, Yamamoto, Hiroyuki, Ogawa, Tadamitsu, Kishimoto   +4 more
openaire   +2 more sources