Results 211 to 220 of about 198,185 (239)

[Hope for chronic inflammatory diseases : the anti-IL-6 receptor monoclonal antibody tocilizumab].

Revue medicale suisse, 2018
Vasculitis like Horton's disease, some autoinflammatory syndromes (Behcet's, Still's diseases) often require long term treatment with steroids, and therefore are associated with non acceptable adverse events, especially when resistant to treatment. Recently, a number of controlled prospective clinical trials are supporting the interest of the anti-IL-6
openaire   +1 more source

Exposure-Exposure Relationship of Tocilizumab, an Anti-IL-6 Receptor Monoclonal Antibody, in a Large Population of Patients With Rheumatoid Arthritis.

Journal of clinical pharmacology
Relationships between tocilizumab exposure and response were evaluated using data from 4 phase III studies. Increased tocilizumab exposure was associated with improvements in Disease Activity Score using 28 joints (DAS28) and American College of Rheumatology (ACR) criteria and with a decrease in inflammation markers.
Micha, Levi, Susan, Grange, Nicolas, Frey   +2 more
openaire   +1 more source

Efficacy of a Recombinant Humanized Anti-IL-6 Receptor Monoclonal Antibody Compared to Hemoperfusion in Severe COVID-19 Pneumonia: Ambispective Cohort Study

Journal of the American Society of Nephrology, 2022
Kanin Thammavaranucupt, Kulapong Jayanama, Ittikorn Spanuchart   +2 more
openaire   +1 more source

Anti-IL-6 receptor monoclonal antibody inhibits leukocyte recruitment and promotes apoptosis in experimental murine colitis

Digestive and Liver Disease, 2000
H. Ito, M. Yamamoto, H. Ogawa, T. Kishimoto   +3 more
openaire   +1 more source

AOSP37 HUMANISED ANTI-VEGF AND ANTI-IL-6 RECEPTOR MONOCLONAL ANTIBODY SUPPRESSED IN-VIVO FLUID RETENTION IN PRIMARY EFFUSION LYMPHOMA

European Journal of Cancer, 2013
H. Goto, E. Kudo, M. Taura, K. Matuda, R. Kariya, S. Okada   +5 more
openaire   +1 more source

Preparation of the Murine Anti-Human P2X7 Receptor Monoclonal Antibody (Clone L4)

Methods in Molecular Biology, 2022
Amal Elhage, Ross J Turner, Peter Cuthbertson   +2 more
exaly  

Faculty Opinions recommendation of Long-term safety and efficacy of tocilizumab, an anti-IL-6 receptor monoclonal antibody, in monotherapy, in patients with rheumatoid arthritis (the STREAM study): evidence of safety and efficacy in a 5-year extension study.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature, 2009
David Scott, Margaret Ma
openaire   +2 more sources

Risk factor analysis for anti-epidermal growth factor receptor monoclonal antibody–induced skin toxicities in real-world metastatic colorectal cancer treatment

Supportive Care in Cancer, 2023
Yoshitaka Saito, Yoh Takekuma, Yoshito Komatsu   +2 more
exaly  

Development of a monoclonal antibody for the detection of anti-canine CD20 chimeric antigen receptor expression on canine CD20 chimeric antigen receptor-transduced T cells

Journal of Veterinary Medical Science, 2021
Toshihiro Tsukui, Masaya Igase, Takuya Mizuno   +2 more
exaly  

Anti-epidermal growth factor receptor (EGFR) monoclonal antibody combined with cisplatin and 5-fluorouracil in patients with metastatic nasopharyngeal carcinoma after radical radiotherapy: a multicentre, open-label, phase II clinical trial

Annals of Oncology, 2019
H Mai, Conghua Xie, Melvin L K Chua
exaly