Arthritis Care &Research, EarlyView.Objective Targeted synthetic disease‐modifying antirheumatic drugs (tsDMARDs) have expanded the management of autoimmune diseases, including rheumatic diseases. As the use of these drugs grows, it is important to understand their effects on pregnancy.
Vienna Cheng +7 more
wiley +1 more source
Role of Antibodies: A Novel Paradigm in Mathematical Modeling for Cancer Treatment [PDF]
arXiv, 2010 A mathematical model for the quantitative analysis of cancer immune interaction, considering the role of antibodies has been proposed in this paper. The model is based on the clinical evidence, which states that antibodies can directly kill cancerous cells [1].
arxiv
A rat monoclonal antibody reacting specifically with the tyrosylated form of alpha-tubulin. I. Biochemical characterization, effects on microtubule polymerization in vitro, and microtubule polymerization and organization in vivo. [PDF]
, 1983 J Wehland +2 more
openalex +1 more source
Advanced Functional Materials, EarlyView.Surface‐attached multilayer micromagnet systems are fabricated by two‐photon crosslinking. The pillar‐shaped micro actuators consist of a soft and flexible surface‐attached cell‐repellent hydrogel layer at the bottom, acting as a hinge and a cell‐adhesive hydrophobic polymer filled with magnetic nanoparticles.
Nicolas Geid +5 more
wiley +1 more source
Monoclonal antibodies. Basic features
Neurología (English Edition), 2011 Introduction: Monoclonal antibodies are a powerful tool in laboratory diagnosis and are increasingly used in the treatment of several diseases. Development: Antibody development and characterization has a long history and goes back to immunology itself ...
A. García Merino
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Mapping of B cell epitopes on small nuclear ribonucleoproteins that react with human autoantibodies as well as with experimentally-induced mouse monoclonal antibodies. [PDF]
, 1989 W J Habets +4 more
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Advanced Functional Materials, EarlyView.The temporary transition of macrophages from a pro‐inflammatory phenotype of macrophages (M1) to an anti‐inflammatory phenotype of macrophages (M2) is crucial for tissue repair and regeneration processes. Bacterial outer membrane vesicles (OMVs) are utilized as a “trojan horse” for specific M1 macrophage‐targeting and anti‐inflammatory drug delivery ...
Donglin Cai +9 more
wiley +1 more source
Cloning of the immunological repertoire in Escherichia coli for generation of monoclonal catalytic antibodies: construction of a heavy chain variable region-specific cDNA library. [PDF]
, 1989 Lakshmi Sastry +8 more
openalex +1 more source
Advanced Functional Materials, EarlyView.A hydrogel for intra‐articular injection for the treatment of rheumatoid arthritis (RA) is formulated and comprehensively studied. After administration, the hydrogel induces a metabolic reprogramming of immunometabolism of macrophages to trigger fatty acid oxidation subsequently inducing polarization of anti‐inflammatory M2 macrophages. This results in
Yutong Song +8 more
wiley +1 more source
Monoclonal Antibodies production technology
Boletim de Indústria Animal, 2011 Since the first cells were capable of maintain a continuous antibody supply, developed by Köhler and Milstein in 1975, its use in medicine and industry showed a great potential.
Flávia Rocha +1 more
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