Results 111 to 120 of about 762,085 (316)

Kinetic Analysis and Epitope Mapping of Monoclonal Antibodies to Salmonella Typhimurium Flagellin Using a Surface Plasmon Resonance Biosensor

open access: yesAntibodies, 2019
Salmonella Typhimurium is one of the leading causes of foodborne diseases worldwide. Biosensors and immunoassays utilizing monoclonal antibodies are widely used for the detection and subtyping of S. Typhimurium.
Devendra Bhandari   +3 more
doaj   +1 more source

Monoclonal antibodies and Fc fragments for treating solid tumors [PDF]

open access: yes, 2012
Andrea M Eisenbeis, Stefan J GrauDepartment of Neurosurgery, University Hospital of Cologne, Cologne, GermanyAbstract: Advances in biotechnology, better understanding of pathophysiological processes, as well as the identification of an increasing number ...
Eisenbeis AM, Grau SJ
core  

Development of a bead-based Luminex assay using lipopolysaccharide specific monoclonal antibodies to detect biological threats from Brucella species [PDF]

open access: yes, 2015
Brucella, a Gram-negative bacterium, is classified as a potential bioterrorism agent mainly due to the low dose needed to cause infection and the ability to transmit the bacteria via aerosols.
Angelika Silbereisen   +9 more
core   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Application of Monoclonal Antibodies in Veterinary Parasitology [PDF]

open access: yesVeterinary World, 2011
The discovery of hybridoma technology by Kohler and Milstein in 1975, heralded a new era in antibody research. Mouse hybridomas were the first reliable source of monoclonal antibodies.
Gupta A.   +2 more
doaj  

An investigation of the molecular basis of interactions between human monoclonal antibodies and antigens that are clinically relevant in systemic lupus erythematosus and the Antiphospholipid Syndrome. [PDF]

open access: yes, 2007
Autontibodies to a wide variety of antigens are associated with systemic lupus erythematosus (SLE) and the Antiphospholipid Syndrome (APS).
Lambrianides, A.
core  

Rat Monoclonal Antibodies Specific for LST1 Proteins [PDF]

open access: yes, 2009
The LST1 gene is located in the human MHC class III region and encodes transmembrane and soluble isoforms that have been suggested to play a role in the regulation of the immune response and are associated with inflammatory diseases such as rheumatoid ...
Seidl, A.   +9 more
core   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

Murine Monoclonal Antibodies: 49 Years of Experience—Is it a Spent Technique? [PDF]

open access: yes
Department of Chemistry and Biochemistry California State UniversityDepartment of Clinical Analysis Monoclonal Antibody Laboratory School of Pharmaceutical Sciences São Paulo State University (UNESP)Department of Clinical Analysis Monoclonal Antibody ...
Brooks, Cory L., Moroz, Andrei [UNESP]
core   +1 more source

Virus-neutralizing monoclonal antibody expressed in milk of transgenic mice provides full protection against virus-induced encephalitis [PDF]

open access: yes, 2001
Neutralizing antibodies represent a major host defense mechanism against viral infections. In mammals, passive immunity is provided by neutralizing antibodies passed to the offspring via the placenta or the milk as immunoglobulin G and secreted ...
Pewe, L   +11 more
core   +1 more source

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