Discovery and characterization of an anti-Neisseria gonorrhoeae NGO_1985 monoclonal antibody and cognate antigen [PDF]
Frontiers in MicrobiologyGonorrhea, caused by the Gram-negative bacterium Neisseria gonorrhoeae (Ng), affects millions of people globally. The absence of a vaccine and the rising antibiotic resistance complicate infection control, highlighting the urgent need for new ...
Pardis Mokhtary +20 more
doaj +2 more sources
Monoclonal antibody (mAb) purification by counter current chromatography (CCC) [PDF]
, 2011 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Counter current chromatography (CCC) is a form of liquid liquid chromatography, which the Brunel Institute for Bioengineering (BIB) team have developed to ...
Fernando, Samantha
core +7 more sources
A new dawn for monoclonal antibodies against antimicrobial resistant bacteria
Frontiers in Microbiology, 2022 Antimicrobial resistance (AMR) is a quickly advancing threat for human health worldwide and almost 5 million deaths are already attributable to this phenomenon every year.
Marco Troisi +6 more
doaj +1 more source
GPI-Anchored Fibromodulin as a Novel Target in Chronic Lymphocytic Leukemia: Diagnostic and Therapeutic Implications [PDF]
Iranian Journal of Immunology, 2019 Background: We have previously reported the aberrant expression of Fibromodulin (FMOD) in patients with chronic lymphocytic leukemia (CLL). Although FMOD has been considered as a cytoplasmic or secretory protein, we discovered the cell surface expression
Lia Farahi +8 more
doaj +1 more source
Frontiers in Microbiology, 2023 Neisseria gonorrhoeae (gonococcus) is an obligate human pathogen and the etiological agent of the sexually transmitted disease gonorrhea. The rapid rise in gonococcal resistance to all currently available antimicrobials has become a significant public ...
Samuele Stazzoni +7 more
doaj +1 more source
Anatomy of Omicron BA.1 and BA.2 neutralizing antibodies in COVID-19 mRNA vaccinees
Nature Communications, 2022 Here, Andreano and Paciello et al. show, at single cell level, the functional and genetic characteristics underlying the Omicron BA.1 and BA.2 cross-protective antibody response in naïve and previously infected COVID-19 vaccinees.
Emanuele Andreano +18 more
doaj +1 more source
Therapeutic Monoclonal Antibodies and Antibody Products, Their Optimization and Drug Design in Cancers [PDF]
, 2022 The book broadly deals with therapeutic monoclonal antibodies (mAbs) and various relevant topics, including different antibody formats such as Antibody–Drug Conjugates (ADC), bispecifics, nanoparticle-based mAbs and HER2+ cancers, immune checkpoint ...
core +1 more source
Frontiers in Immunology, 2021 Monoclonal antibodies (mAbs) have been a valuable tool to elucidate several biological processes, such as stem cell differentiation and cancer, and contributed to virtually all areas of biomedical sciences.
Marina de Lima Fontes +7 more
doaj +1 more source
mRNA vaccines and hybrid immunity use different B cell germlines against Omicron BA.4 and BA.5
Nature Communications, 2023 Omicron strains of SARS-CoV-2 have displayed high transmissibility and immunological escape to antibody responses derived from natural infection and vaccination.
Emanuele Andreano +15 more
doaj +1 more source
Recent Progress in the Discovery and Development of Monoclonal Antibodies against Viral Infections
Biomedicines, 2022 Monoclonal antibodies (mAbs), the new revolutionary class of medications, are fast becoming tools against various diseases thanks to a unique structure and function that allow them to bind highly specific targets or receptors.
Pardis Mokhtary +4 more
doaj +1 more source