Results 11 to 20 of about 735,469 (267)
Establishing a novel and sensitive assay for bioactivity determination of anti-CD25 antibodies
Heliyon, 2023 Anti-CD25 antibodies have been approved for renal transplantation and has been used prior to and during transplantation by the Food and Drug Administration (FDA).
Maoqin Duan +11 more
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Heliyon, 2023 Anti-drug antibody (ADA) positivity is correlated with disease relapse risk when treated with monoclonal antibody (mAb) therapeutics. ADA evaluation can assist with interpreting pharmacokinetic, pharmacological, and toxicology results.
Jialiang Du +10 more
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Frontiers in Chemistry, 2022 Succinimide (Asu) is the intermediate for asparagine deamidation in therapeutic proteins, and it can be readily hydrolyzed to form aspartate and iso-aspartate residues. Moreover, Asu plays an important role in the protein degradation pathways, asparagine
Tao Liu +22 more
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Human monoclonal antibodies and monoclonal antibody multispecificity [PDF]
British Journal of Cancer, 1987 The majority of human anti-tumour monoclonal antibodies (Mabs) isolated to date have been disappointing. Firstly, they react or cross react with intracellular cytoskeletal proteins or nuclear antigens and therefore are of limited value as blood borne agents.
A M, Campbell, P, Whitford, R E, Leake
openaire +2 more sources
Pharmaceutics, 2022 The higher-order structure (HOS) of protein therapeutics has been confirmed as a critical quality parameter. In this study, we compared 2D 1H-13C ALSOFAST-HMQC NMR spectra with immunochemical ELISA-based analysis to evaluate their sensitivity in ...
Francesca Cantini +6 more
doaj +1 more source
Production and characterization of polyclonal antibody against a synthetic peptide from β-actin protein [PDF]
Iranian Journal of Basic Medical Sciences, 2014 Objective(s):Antibodies against actin, as one of the most widely studied structural and multifunctional housekeeping proteins in eukaryotic cells, are used as internal loading controls in western blot analyses.
Nazila Amini +6 more
doaj
Establishment and Functional Characterization of Murine Monoclonal Antibodies Recognizing Neuritin
Antibodies, 2023 Neuritin represents a neurotrophic factor that is not only important in neuronal development and plasticity but also impacts endothelial angiogenesis, cell migration, tumor growth and the production of antibodies by B cells.
Georgia Papadogianni +6 more
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One Health Outlook, 2023 Our planet is populated by at least a trillion species of microorganisms. Every life form is sustained by them and they make the planet habitable. Only a minority of them, about 1400 species, cause infectious diseases that are responsible for human ...
Rino Rappuoli +4 more
doaj +1 more source
Frontiers in Plant Science, 2022 Monoclonal antibodies are considered to be highly effective therapeutic tools for the treatment of mild to moderate COVID-19 patients. In the present work, we describe the production of two SARS-CoV-2 human IgG1 monoclonal antibodies recognizing the ...
Rachele Frigerio +12 more
doaj +1 more source
A Systematic Review of Circulating Tumor Cells in Renal Cell Carcinoma
Translational Research in Urology, 2021 Introduction Renal cell carcinoma (RCC) is one of the most usual kidney’s tumors. The improvement of non-invasive biomarkers will make it feasible to investigate whose have high risk of recurrence after radical or partial nephrectomy and will expand the
Seyed Mohammad Kazem Aghamir +2 more
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