Results 191 to 200 of about 1,119,690 (306)

Biomimetic Copper Nanoparticles Coated with ACE2‐Overexpressing Membranes for Selective SARS‐CoV‐2 Neutralization and Disinfection

Advanced Healthcare Materials, EarlyView.
By fusing ACE2‐overexpressing membrane‐integrated liposome (MIL) with copper nanoparticles, the biomimetic Cu@MIL nanostructures were created that directly hijack the SARS‐CoV‐2 entry pathway. These particles combine potent virus‐targeting precision with intrinsic antiviral activity, achieving rapid neutralization and disinfection.
Pooja Aich, Wei‐Pang Chung, Wen‐Jyun Wang, Hidenobu Takahashi, Ming‐Shun Hsieh, Ying‐Chen Lin, Oh Seok Kwon, Wei‐Peng Li, Wei‐Lun Huang   +8 more
wiley   +1 more source

A Human Monoclonal Antibody Targeting α-Gal Ameliorates Experimental Cutaneous Leishmaniasis. [PDF]

J Infect Dis
Cho H, Paun A, Seo Y, Lee SH, Traver M, Zhao M, Skinner J, Tan J, Sacks DL, Crompton PD.   +9 more
europepmc   +1 more source

A New 3D Colon on a Chip to Decipher the Influence of Mechanical Forces on the Physiological Cellular Ecosystem

Advanced Healthcare Materials, EarlyView.
To dissect how mechanical forces influence intestinal physiology, we developed a stretchable 3D colon‐on‐chip that integrates tunable topography, stiffness and peristalsis‐like motion within a physiologically relevant microenvironment. We showed that stretching is a dominant factor governing epithelial behavior, markedly enhancing proliferation and ...
Moencopi Bernheim‐Dennery, Lauriane Gérémie, Julie Brun, Lucas Chassatte, Giacomo Gropplero, Réda Bouras, Jieun Choo, Bertrand Cinquin, Alba Marcellan, Danijela Matic Vignjevic, Stéphanie Descroix   +10 more
wiley   +1 more source

Monoclonal antibody preparation and linear epitope identification for the ASFV A151R protein. [PDF]

BMC Vet Res
Liu Z, You J, Zhang W, Gao C, Huang S, Gong L, Chen X, Zhang G, Huang Y, Huang Z.   +9 more
europepmc   +1 more source

Designed Liquid Crystalline Nanoassemblies From Clinically Validated Polyunsaturated Lipids for Combined Antioxidant, Anti‐Apoptotic, and Neurotrophic Treatments

Advanced Healthcare Materials, EarlyView.
Ionizable lipid nanoparticles target multiple pathological pathways in neurodegeneration. The designed self‐assembled materials undergo a pH‐triggered structural transformation from a cubosome/hexosome coexistence to a hexosome phase, enhancing intracellular delivery of a multi‐target phytochemical formulation. The antioxidant‐loaded pH‐responsive LNPs
Thelma Akanchise, Fucen Luo, Borislav Angelov, Yuru Deng, Angelina Angelova   +4 more
wiley   +1 more source

Preclinical characterisation of the protective capacity of an anti-nucleoprotein hRSV monoclonal antibody. [PDF]

EBioMedicine
Farías MA, Andrade CA, Loaiza RA, Rodríguez-Guilarte L, Muñoz JT, Pereira-Sánchez P, Muñoz-Durango N, Pizarro-Ortega MS, Diethelm-Varela B, Pereira-Serrano A, Ramírez RA, Chávez JL, Bohmwald K, Soto JA, González PA, Bueno SM, Kalergis AM.   +16 more
europepmc   +1 more source

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

Monoclonal antibody inhibition of PAR2 reduces phenotype severity and pain in murine inflammatory bowel disease. [PDF]

Pain Rep
Ritoux A, Grundy LJ, Manjappa P, Paine LW, Neisen J, Linley JE, Smith ESJ.   +6 more
europepmc   +1 more source

Tuning the Testicular Microenvironment for Enhancing Human Sertoli Cells Maturation and Functionality In Vitro

Advanced Healthcare Materials, EarlyView.
An in vitro testicular model is developed by generating connective tissue equivalents from human dermal fibroblast‐derived microtissues and coupling them with human Sertoli cells or human Sertoli cell spheroids. This engineered microenvironment supports Sertoli cell maturation and functionality, providing a promising platform for studying human ...
Annachiara Scalzone, Giorgia Imparato, Chiara Ausilio, Valentina Mollo, Paolo Antonio Netti   +4 more
wiley   +1 more source

Development and characterization of a novel B7-H3 rabbit monoclonal antibody for glioma diagnosis. [PDF]

Front Pharmacol
Li Y, Wang Z, Wen Q, Chiu M, Jia X, Li Y, Shang X.   +6 more
europepmc   +1 more source