Results 201 to 210 of about 2,681,651 (342)

High-efficiency gene transfer by adenovirus coupled to DNA-polylysine complexes [PDF]

open access: yes, 1992
Agarwal, Santosh   +7 more
core   +1 more source

Novel Bioconjugate Materials: Synthesis, Characterization and Medical Applications

open access: yesAdvanced Healthcare Materials, EarlyView.
This review discusses the bioconjugation of novel materials grouped under “biological”, “hybrid” and “synthetic” categories. Medical applications ranging from cancer therapy and diagnostics to optogenetics and tissue engineering are explored, and conjugation trends are highlighted as a general guide. The review concludes with a comparison of techniques
Ellie Martin   +6 more
wiley   +1 more source

Fluid Shear‐Controlled Pro/Anti‐Inflammatory Osteomodulatory Construct for Drug‐Free Immune Activation Through Cationic Ion Channel Activation

open access: yesAdvanced Healthcare Materials, EarlyView.
A 3D‐printed PCL scaffold coated with Arginine was laminated with electrospun polyvinyl alcohol (PVA) nanofibers containing cationic cellulose nanocrystals (PVA@cCNC). This created nanoisland‐like regions of aligned and random cCNC‐rich fibers. The composite scaffold, under fluid shear stimulation, modulated macrophage polarization from M1 to M2 ...
Keya Ganguly   +8 more
wiley   +1 more source

Optimising Monoclonal Antibody Drug Development for Inflammatory Bowel Disease. [PDF]

open access: yesClin Exp Gastroenterol
Colwill M   +3 more
europepmc   +1 more source

Pulmonary Delivery of siRNA Anti‐TNFα‐loaded Lipid Nanoparticles for Rapid Recovery in Murine Acute Lung Injury

open access: yesAdvanced Healthcare Materials, EarlyView.
In a murine model of acute lung injury, pulmonary administration of lipid nanoparticles carrying TNFα siRNA enables targeted delivery to immune cells. The study emphasises the importance of optimizing LNP distribution and delivery timing to improve therapeutic outcomes and develop emergency therapies for lung hyperinflammation.
Qinglin Wang   +14 more
wiley   +1 more source

An Asymptotic Analysis of Bivalent Monoclonal Antibody-Antigen Binding. [PDF]

open access: yesBull Math Biol
Heirene LA   +3 more
europepmc   +1 more source

Differential Phase Contrast Imaging to Predict MSC Immune Function

open access: yesAdvanced Healthcare Materials, EarlyView.
This work employs quantitative differential phase contrast (qDPC) imaging technique to non‐invasively extract morphological features from live Mesenchymal Stromal Cells (MSCs) for single cell prediction on cell immunomodulatory capacity. This work establishes a foundation for scalable, non‐destructive monitoring of MSCs immunomodulatory capacity ...
Kejie Rui   +5 more
wiley   +1 more source

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