Results 211 to 220 of about 759,957 (341)

Depletion of Hepatic SREBP2 Protects Against Hypercholesterolemia and Atherosclerosis through the ANGPTL3‐LPL Axis

Advanced Science, EarlyView.
This study reveals a novel crosstalk between hepatic SREBP2‐mediated cholesterol biosynthesis pathway and peripheral lipoprotein lipase‐mediated lipolysis pathway in the regulation of systemic lipid metabolism. Notably, the lipid‐lowering effects of SREBP2 inhibition are independent of a functional LDL receptor, highlighting the potential of acute ...
Yifan Wang, Jia You Sarafina Choe, Yu Shi, Thi Tun Thi, Xiaoyun Cao, Yang Hu, Kai Yan Cheng, Hui Li, Yang Ji, Yan Liu, Matthew Ackers‐Johnson, Roger S.Y. Foo, Yujia Shen, Haojie Yu   +13 more
wiley   +1 more source

Immunobridging for Pemivibart, a Monoclonal Antibody for Prevention of Covid-19. [PDF]

N Engl J Med
Schmidt P, Li Y, Popejoy M.
europepmc   +1 more source

Monoclonal Antibodies in Dermatology [PDF]

Journal of the Royal Society of Medicine, 1983
openaire   +2 more sources

Human monoclonal antibodies that protect mice against challenge with Pseudomonas aeruginosa

, 1988
Hans J. Zweerink, Maureen C. Gammon, Cameron F. Hutchison, J. J. Jackson, D. Lombardo, Karen M. Miner, J M Puckett, T J Sewell, N H Sigal   +8 more
openalex   +1 more source

Ultrastructural Analysis of Normal and Leukaemic Cells by the Immunogold Method and Monoclonal Antibodies [PDF]

, 1985
E Matutes, D Catovsky
openalex   +1 more source

PPY‐Induced iCAFs Cultivate an Immunosuppressive Microenvironment in Pancreatic Cancer

Advanced Science, EarlyView.
Pancreatic ductal adenocarcinoma features abundant stromal components that hinder therapy efficacy. Single‐cell RNA sequencing analysis combined with experiments identified PPY, a gastrointestinal hormone, as a novel inducer of immunosuppressive iCAFs. Mechanistic studies revealed that PPY activates the non‐canonical NF‐κB pathway via EGFR.
Mengdie Cao, Wang Peng, Bin Cheng, Ronghua Wang, Wei Chen, Luyao Liu, Hai Huang, Shiru Chen, Haochen Cui, JingWen Liang, Qiaodan Zhou, Si Xiong, Shuya Bai, Luoxia Liu, Yuchong Zhao   +14 more
wiley   +1 more source

Development of a Monoclonal Antibody Against Duck IFN-γ Protein and the Application for Intracellular Cytokine Staining. [PDF]

Animals (Basel)
Chen Y, Song W, Chen J, Jin C, Lin J, Liao M, Dai M.   +6 more
europepmc   +1 more source

Reversible inhibition of oligodendrocyte progenitor differentiation by a monoclonal antibody against surface galactolipids. [PDF]

, 1989
Rashmi Bansal, S. E. Pfeiffer
openalex   +1 more source

A CLDN18.2‐Targeted Nanoplatform Manipulates Magnetic Hyperthermia Spatiotemporally for Synergistic Immunotherapy in Gastric Cancer

Advanced Science, EarlyView.
CLDN18.2 is a highly selective biomarker exposed in gastric cancer. A CLDN18.2‐specific antibody 1D5 conjugated fluorescence‐magnetic nanoparticle is developed for image‐guided precision theragnostics. Under the assistance of sensitive FMI and deep‐penetrating MPI for tracing and timing the optimal nanoparticle dosage, combining α‐PD1 therapy with ...
Xueying Wang, Hui Hui, Jing Han, Ting Guo, Yiding Wang, Lin Meng, Cong Chen, Jie He, Xiaoyong Guo, Fuyu Zhong, Hong Du, Jie Tian, Xiaofang Xing, Yang Du, Jiafu Ji   +14 more
wiley   +1 more source

Development of an anti-human EphA2 monoclonal antibody Ea₂Mab-7 for multiple applications. [PDF]

Biochem Biophys Rep
Satofuka H, Suzuki H, Tanaka T, Li G, Kaneko MK, Kato Y.   +5 more
europepmc   +1 more source