Results 231 to 240 of about 1,325,739 (304)

Technologies for Monoclonal Antibody Discovery and Development. [PDF]

open access: yesInt J Mol Sci
Han KH   +4 more
europepmc   +1 more source

Integrated Single‐Cell and TCR Profiling Reveals Protection‐Associated CD8+ T Cell Subsets Linked to Viral Control in PRRSV

open access: yesAdvanced Science, EarlyView.
PRRSV vaccine‐mediated protection is associated with clonally expanded cytotoxic CD8+ T cell subsets driven by viral structural proteins and supported by innate TLR4/TLR8 signaling and CD4+ T cell help, whereas non‐protective responses are characterized by dysfunctional exhausted‐like CD8+ T cells linked to poor viral control.
Can Kong   +14 more
wiley   +1 more source

Trafficking Deficiency of TMEM175 Variants in Parkinson's Disease Pathogenesis and the Prospects of Precision Medicine

open access: yesAdvanced Science, EarlyView.
This study identifies that the PD‐associated TMEM175‐L156P variant disrupts lysosomal ion channel trafficking by causing aberrant endoplasmic reticulum retention. A “chaperone–agonist” bifunctional small molecule restores TMEM175‐L156P lysosomal localization and channel function, thereby alleviating PD‐relevant cellular phenotypes and highlighting a ...
Ting Luo   +17 more
wiley   +1 more source

Monoclonal antibody therapy for PCOS? [PDF]

open access: yesCell Metab
Abbott DH, Dumesic DA.
europepmc   +1 more source

Acceptance of the respiratory syncytial virus infant monoclonal antibody nirsevimab among post-partum women in Italy. [PDF]

open access: yesHum Vaccin Immunother
Angelillo S   +4 more
europepmc   +1 more source

Anti-PD-1 monoclonal antibody suppresses hepatitis B virus in patients with hepatocellular carcinoma. [PDF]

open access: yesChin Med J (Engl)
Zhao C   +12 more
europepmc   +1 more source

Treatment with saturating dose of conventional anti-CD28 monoclonal antibody well tolerated in pig acute myocardial infarction model. [PDF]

open access: yesFront Immunol
Stadtmüller A   +16 more
europepmc   +1 more source

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