Results 11 to 20 of about 13,966 (231)

Monoclonal gammopathy of undetermined significance [PDF]

Blood, 2019
Abstract Monoclonal gammopathy of undetermined significance (MGUS) is a premalignant plasma cell dyscrasia that consistently precedes multiple myeloma (MM) with a 1% risk of progression per year. Recent advances have improved understanding of the complex genetic and immunologic factors that permit progression from the aberrant plasma ...
Tarek H, Mouhieddine, Lachelle D, Weeks, Irene M, Ghobrial   +2 more
semanticscholar   +4 more sources

Neurovisceral Syndrome in a Patient with Monoclonal Gammopathy of Undetermined Significance: A Confirmed Case of Variegate Porphyria. [PDF]

Cureus
Fatima I, Awais KAD, Sehbai A, Tareen AAK, Shaharyar M.   +4 more
europepmc   +2 more sources

Diagnosis and Management of Monoclonal Gammopathy of Undetermined Significance: A Review. [PDF]

JAMA Intern Med
Importance Nearly 5% of adults have the precursor malignant condition monoclonal gammopathy of unknown significance (MGUS). Management centers on differentiating MGUS from more serious conditions to determine additional diagnostic testing, monitoring ...
Liu Y, Parks AL.
europepmc   +2 more sources

Defining the proteome of bone marrow plasma in multiple myeloma and monoclonal gammopathy of undetermined significance. [PDF]

Blood Cancer J
Hsu JS, Yadav U, Garapati K, Mangalaparthi KK, Chawla Y, Wiedmeier-Nutor JE, Fonseca R, Bergsagel PL, Rajkumar SV, Kumar S, Gonsalves WI, Pandey A, Kandasamy RK.   +12 more
europepmc   +3 more sources

A case of immunotactoid glomerulopathy in a patient with monoclonal gammopathy of renal significance

Journal of Community Hospital Internal Medicine Perspectives, 2021
Monoclonal gammopathy of renal significance is a relatively new diagnosis that attributes kidney disease to damage caused by a monoclonal protein. There is growing recognition of this disease in patients previously diagnosed with monoclonal gammopathy of
Victoria Campdesuner, Yeshanew Teklie, Natalia Lattanzio, Christian Lorenzo, Stephen Bell, Yorlenis Rodriguez, Ashok Sastry   +6 more
doaj   +1 more source

Monoclonal gammopathies of clinical significance (MGCS): In pursuit of optimal treatment

Frontiers in Immunology, 2022
Monoclonal gammopathy of clinical significance (MGCS) represents a new clinical entity referring to a myriad of pathological conditions associated with the monoclonal gammopathy of undetermined significance (MGUS).
Artem Oganesyan, Artem Oganesyan, Andrew Gregory, Florent Malard, Nerses Ghahramanyan, Mohamad Mohty, Dickran Kazandjian, Arsène Mekinian, Arsène Mekinian, Yervand Hakobyan, Yervand Hakobyan   +10 more
doaj   +1 more source

Asymptomatic Incidence of Monoclonal Gammopathy of Undetermined Significance and Preclinical Duration to Myeloma Diagnosis: A Modeling Study. [PDF]

Cancer Epidemiol Biomarkers Prev
Ji M, Shih YH, Huber JH, Wang M, Feuer EJ, Etzioni R, Wang SY, Chang SH.   +7 more
europepmc   +3 more sources

Direct Mass Spectrometry-Based Detection and Antibody Sequencing of Monoclonal Gammopathy of Undetermined Significance from Patient Serum: A Case Study

bioRxiv, 2023
Monoclonal gammopathy of undetermined significance (MGUS) is a plasma cell disorder, characterized by the presence of a predominant monoclonal antibody (i.e., M-protein) in serum, without clinical symptoms. Here we present a case study in which we detect

semanticscholar   +1 more source

Electrophoretical distribution of serum monoclonal protein and underlying causes. Data from a referral center in Mexico

Medicina Universitaria, 2022
Background: Monoclonal gammopathies are a group of disorders characterized by an overproduction of monoclonal immunoglobulin. Detection and quantification of monoclonal components using serum protein electrophoresis (SPE) for screening is the initial ...
Luz Tarín-Arzaga, Carlos de la Cruz-de la Cruz, Odra Martínez-González, David Gómez-Almaguer   +3 more
doaj   +1 more source

Kidney Biopsy in Patients With Monoclonal Gammopathy: A Multicenter Retrospective Cohort Study

Frontiers in Medicine, 2021
Objectives: To analyze the clinical characteristics and renal pathological manifestations of patients with monoclonal gammopathy (MG) and kidney injury.Methods: This was a multicenter retrospective cohort study conducted at four tertiary hospitals in ...
Sheng Nie, Mengyi Wang, Qijun Wan, Qijun Wan, Yaozhong Kong, Jun Ou, Nan Jia, Xiaodong Zhang, Fan Luo, Xiaoting Liu, Lin Wang, Yue Cao, Ruixuan Chen, Mingpeng Zhao, David Yiu Leung Chan, Guobao Wang   +15 more
doaj   +1 more source