Results 81 to 90 of about 13,966 (231)

Patterns of survival and causes of death following a diagnosis of monoclonal gammopathy of undetermined significance: a population-based study

Haematologica, 2009
Background There are limited data on survival patterns among patients with monoclonal gammopathy of undetermined significance.Design and Methods We compared the survival of 4,259 patients with monoclonal gammopathy of undetermined significance ...
Sigurdur Y. Kristinsson, Magnus Björkholm, Therese M-L Andersson, Sandra Eloranta, Paul W. Dickman, Lynn R. Goldin, Cecilie Blimark, Ulf-Henrik Mellqvist, Anders Wahlin, Ingemar Turesson, Ola Landgren   +10 more
doaj   +1 more source

Coinherited genetics of multiple myeloma and its precursor, monoclonal gammopathy of undetermined significance.

Blood Advances, 2020
So far, 23 germline susceptibility loci have been associated with multiple myeloma (MM) risk. It is unclear whether the genetic variation associated with MM susceptibility also predisposes to its precursor, monoclonal gammopathy of undetermined ...
A. Clay-Gilmour, A. Clay-Gilmour, M. Hildebrandt, E. Brown, J. Hofmann, J. Spinelli, Graham G. Giles, Graham G. Giles, Graham G. Giles, W. Cozen, P. Bhatti, Xifeng Wu, Rosalie G. Waller, Alem A Belachew, Dennis P Robinson, A. Norman, J. Sinnwell, S. Berndt, S. Rajkumar, Shaji K. Kumar, S. Chanock, M. Machiela, R. Milne, R. Milne, R. Milne, S. Slager, N. Camp, E. Ziv, C. Vachon   +28 more
semanticscholar   +1 more source

Identification of Potential Ferroptosis Biomarkers in Multiple Myeloma via WGCNA and Experiments

Cancer Reports, Volume 9, Issue 1, January 2026.
ABSTRACT Introduction Multiple myeloma is a common malignant tumor of the hematologic system, and genetic alterations play a crucial role in its occurrence and development. Ferroptosis is an oxidative and iron‐dependent programmed cell death, which has a strong correlation with tumor development.
Yifan Wang, Xing Xie, Mengyuan Gu, Yanting Zheng, Jing Wu, Qicai Wang, Zhian Ling, Ruolin Li   +7 more
wiley   +1 more source

Detection and prevalence of monoclonal gammopathy of undetermined significance: a study utilizing mass spectrometry-based monoclonal immunoglobulin rapid accurate mass measurement

Blood Cancer Journal, 2019
High-sensitivity mass spectrometry assays are available to detect monoclonal immunoglobulins. To better assess the prevalence of monoclonal gammopathy of undetermined significance (MGUS), we identified 300 patients diagnosed with MGUS or related ...
D. Murray, Shaji K. Kumar, R. Kyle, A. Dispenzieri, S. Dasari, D. Larson, C. Vachon, J. Cerhan, S. Rajkumar   +8 more
semanticscholar   +1 more source

Navigating the evolving management of smoldering multiple myeloma

HemaSphere, Volume 10, Issue 1, January 2026.
Abstract Smoldering multiple myeloma (SMM) represents an intermediate clinical stage between monoclonal gammopathy of undetermined significance (MGUS) and symptomatic multiple myeloma (MM). SMM carries a highly variable risk of progression to MM, requiring individualized risk stratification to guide management.
M. Bakri Hammami, Rafael R. Canevarolo, Ariosto S. Silva, Melissa Alsina, Nagi Kumar, Rachid Baz, Kenneth H. Shain   +6 more
wiley   +1 more source

Monoclonal gammopathy of clinical and undetermined significance [PDF]

, 2023
Alissa Visram
openalex   +1 more source

If treating obesity with GLP‐1‐based therapies protects the heart, could it also prevent cancer or improve cancer outcomes? The case for randomized trials

Diabetes, Obesity and Metabolism, EarlyView.
Anastasios Tentolouris, Ioannis Ntanasis‐Stathopoulos   +1 more
wiley   +1 more source

Analysis of the immune system of multiple myeloma patients achieving long-term disease control by multidimensional flow cytometry

Haematologica, 2013
Multiple myeloma remains largely incurable. However, a few patients experience more than 10 years of relapse-free survival and can be considered as operationally cured.
Roberto J. Pessoa de Magalhães, María-Belén Vidriales, Bruno Paiva, Carlos Fernandez-Gimenez, Ramón García-Sanz, Maria-Victoria Mateos, Norma C. Gutierrez, Quentin Lecrevisse, Juan F Blanco, Jose Hernández, Natalia de las Heras, Joaquin Martinez-Lopez, Monica Roig, Elaine Sobral Costa, Enrique M. Ocio, Martin Perez-Andres, Angelo Maiolino, Marcio Nucci, Javier De La Rubia, Juan-Jose Lahuerta, Jesús F. San-Miguel, Alberto Orfao   +21 more
doaj   +1 more source

Mapping VEXAS‐associated and rare UBA1 variants in the United Kingdom: Insights from patient cohorts and the general population

British Journal of Haematology, Volume 208, Issue 1, Page 116-128, January 2026.
VEXAS syndrome is a late‐onset inflammatory disorder with rheumatological and haematological features. Epidemiological studies of VEXAS syndrome so far have been limited. Analysis of various UK cohorts estimates the incidence of VEXAS to be 1.51/100 000, or 171 new cases in the population of men over the age of 50 who are being investigated for myeloid
Ana Martinez Rodriguez, Leon Chang, Dorota Rowczenio, Alexandra Smith, Ebun Omoyinmi, James A. Poulter, Andrew McGregor, Sebastian Francis, Roochi Trikha, Adam Al‐Hakim, Kar Lok Kong, David G. Kent, Helen Lachmann, Austin Kulasekararaj, Catherine Cargo, Sinisa Savic   +15 more
wiley   +1 more source

IL21R expressing CD14+CD16+ monocytes expand in multiple myeloma patients leading to increased osteoclasts

Haematologica, 2017
Bone marrow monocytes are primarily committed to osteoclast formation. It is, however, unknown whether potential primary alterations are specifically present in bone marrow monocytes from patients with multiple myeloma, smoldering myeloma or monoclonal ...
Marina Bolzoni, Domenica Ronchetti, Paola Storti, Gaetano Donofrio, Valentina Marchica, Federica Costa, Luca Agnelli, Denise Toscani, Rosanna Vescovini, Katia Todoerti, Sabrina Bonomini, Gabriella Sammarelli, Andrea Vecchi, Daniela Guasco, Fabrizio Accardi, Benedetta Dalla Palma, Barbara Gamberi, Carlo Ferrari, Antonino Neri, Franco Aversa, Nicola Giuliani   +20 more
doaj   +1 more source