Results 81 to 90 of about 130,905 (336)

Biomimetic Bone Marrow Monocyte Membrane‐Fused Extracellular Vesicles for Targeted Therapy of Myocardial Infarction

open access: yesAdvanced Science, EarlyView.
This study develops a biomimetic delivery system (M‐hEV) by fusing monocyte membranes with extracellular vesicles for targeted therapy of damaged cardiac tissue. The system homes to injured myocardium through specific molecular pathways. In a myocardial infarction model, M‐hEV effectively accumulates in the heart, reduces infarct size, alleviates ...
Jiaxin Song   +10 more
wiley   +1 more source

The Diagnostic Value of Monocyte Chemoattractant Protein-1, Compared with Procalcitonin, C-reactive Protein, and Lactate in Bacteremia Estimation for Patients with Febrile Neutropenia

open access: yesRomanian Journal of Laboratory Medicine, 2020
Bacteremia in the febrile neutropenic patients significantly increases the mortality. It takes a long time to complete the blood culture for the diagnosis of bacteremia.
Ödemiş İlker   +4 more
doaj   +1 more source

Chemokine expression by systemic sclerosis fibroblasts: Abnormal regulation of monocyte chemoattractant protein 1 expression

open access: yes, 2001
Objective: Chemokines are important mediators in the chemoattraction of leukocytes to sites of inflammation. This study investigated the potential contribution of systemic sclerosis (SSc) fibroblasts to chemokine production and its potential relevance to
Alcami, José   +5 more
core   +1 more source

Reprogramming the Immune Landscape of Inflammatory Breast Cancer

open access: yesAdvanced Science, EarlyView.
Inflammatory breast cancer is the most lethal subtype of breast cancer and is characterized by an immunosuppressive tumor microenvironment (TME) driven by a complex network of immune cells and inflammatory cytokines, contributing to its aggressiveness and treatment challenges. Immune checkpoint inhibitors, either alone or in combination, show potential
Verena Martinez‐Rodriguez   +3 more
wiley   +1 more source

Principal component analysis of adipocytokines and insulin associate with risk factors of cardiovascular diseases

open access: yesBMC Research Notes, 2020
Objectives Obesity plays an important role in the development of chronic diseases like cardiovascular diseases and diabetes. The possible underlying mechanism for this connection is that adipose tissue secretes an array of chemical messenger adipokines ...
Habib Yarizadeh   +7 more
doaj   +1 more source

Complement 5a Enhances Hepatic Metastases of Colon Cancer via Monocyte Chemoattractant Protein-1-mediated Inflammatory Cell Infiltration*

open access: yesJournal of Biological Chemistry, 2015
Background: It is known that the complement system contributes to tumor progression, but the exact mechanism is still unclear. Results: Complement 5a enhances tumor metastasis via monocyte chemoattractant protein-1-mediated inflammatory cell infiltration.
C. Piao   +5 more
semanticscholar   +1 more source

Influence of the Atrial Natriuretic Peptide on TNF- αα α -activated human endothelial cells [PDF]

open access: yes, 2002
The present work deals with the inhibitory action of ANP on TNF- -induced expression of adhesion molecules (ICAM-1, VCAM-1, E-selectin), chemokines (MCP-1), and cytoskeleton changes in human endothelial cells. 5.1.1 Effect of ANP on TNF- α αα-induced CAM
Weber, Nina Claudia
core  

Wavelength‐Dependent Photobiomodulation Regulates Macrophage Polarization via Mitochondrial Dynamics and Metabolic Reprogramming

open access: yesAdvanced Science, EarlyView.
Light wavelength encodes distinct macrophage fates through mitochondrial and metabolic remodeling. Red 625 nm irradiation induces glycolysis, mitochondrial fission, and M1 polarization, whereas near‐infrared 850 nm irradiation promotes fatty acid oxidation, mitochondrial fusion, and M2 polarization.
Qiusheng Shi   +12 more
wiley   +1 more source

Monocyte Chemoattractant Protein 1 (MCP-1) in Obesity and Diabetes

open access: yesCytokine, 2012
Monocyte chemoattractant protein-1 (MCP-1) is the first discovered and most extensively studied CC chemokine, and the amount of studies on its role in the etiologies of obesity- and diabetes-related diseases have increased exponentially during the past 2
J. Panee
semanticscholar   +1 more source

Endogenous monocyte chemoattractant protein-1 recruits monocytes in the zymosan peritonitis model [PDF]

open access: yesJournal of Leukocyte Biology, 1998
Abstract The role of monocyte chemoattractant protein-1 (MCP-1) in the recruitment of blood-derived monocytes in a model of zymosan peritoneal inflammation was investigated. After zymosan injection (1 mg) a rapid influx of polymorphonuclear leukocytes (PMN) and monocytes into the peritoneal cavity associated with mouse MCP-1 (JE) gene ...
M N, Ajuebor   +6 more
openaire   +2 more sources

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