Results 71 to 80 of about 130,905 (336)

Influence of HFE variants and cellular iron on monocyte chemoattractant protein-1

Journal of Neuroinflammation, 2009
Background Polymorphisms in the MHC class 1-like gene known as HFE have been proposed as genetic modifiers of neurodegenerative diseases that include neuroinflammation as part of the disease process.
Simmons Zachary, Randazzo William T, Lee Sang Y, Mitchell Ryan M, Connor James R   +4 more
doaj   +1 more source

Perivascular Matrix Densification Dysregulates Angiogenesis and Activates Pro‐Inflammatory Endothelial Cells

Advanced Science, EarlyView.
Perivascular matrix densification promotes the emergence of aberrant endothelial tip cells (ATECs) that invade and persist within fibrotic microenvironments. Using in vivo lineage tracing and a human microvessel model, this study shows that fibrous matrix cues destabilize VE‐cadherin–mediated junctions to gate TGF‐β signaling, inducing a pro ...
Jingyi Xia, William Y. Wang, Kyle A. Jacobs, Kairav Maniar, Daphne Lin, Evan H. Jarman, Daniel L. Matera, Kristen Loesel, Christopher D. Davidson, Harrison L. Hiraki, Xiaotian Tan, Eve H. Shikanov, Robert N. Kent, Carole Parent, Xudong Fan, Ariella Shikanov, Matthew L. Kutys, Brendon M. Baker   +17 more
wiley   +1 more source

Estimation of Serum leukotriene and some interleukin Levels in Women Infected with Trichomonas vaginalis Parasite

Academic Science Journal
This case-control study aimed to estimate serum leukotrines IgG, IgA, IgM, Leukotrienes, Interlukin-10, Interlukin-IB and monocyte chemoattractant protein-1 (MCP) in women infected with Trichomonas vaginalis parasite.
Asraa Dawod Farhan
doaj   +1 more source

Teràpia gènica amb hHGF en models de dany renal [PDF]

, 2010
La isquèmia renal és una de les principals causes del Fracas Renal Agut i en el context del trasplantament renal predisposa l’òrgan a un dany crònic i a una possible pèrdua de l’empelt. La cèl•lula epitelial tubular representa una de la unitats renals
Franquesa Bartolomé, Marcela, Franquesa, Marcella   +1 more
core  

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Role of Monocyte Chemoattractant Protein-1 in Myocardial Infarction

International Journal of Biomedical Science, 2007
Myocardial infarction (MI) is accompanied by inflammatory responses that lead to the recruitment of leukocytes and subsequent myocardial damage, healing, and scar formation. Chemokines are a family of potent chemoattractant cytokines that regulate the leukocyte trafficking in basal levels and inflammatory processes; however, it has been recently ...
Hajime, Morimoto, Masafumi, Takahashi
openaire   +2 more sources

Bindarit inhibits human coronary artery smooth muscle cell proliferation, migration and phenotypic switching [PDF]

, 2012
Bindarit, a selective inhibitor of monocyte chemotactic proteins (MCPs) synthesis, reduces neointimal formation in animal models of vascular injury and recently has been shown to inhibit in-stent late loss in a placebo-controlled phase II clinical trial.
DI LAURO M. V., Maria Vittoria Di Lauro (127364), Teresa Iuvone (127378), Angelo Guglielmotti, Angelo Guglielmotti (127381), Pasquale Maffia (127384), Gianluca Grassia (127362), Cicala, C., MADDALUNO, MARCELLA, Francesco Maione, Maria Vittoria Di Lauro, Nicola Mascolo, Nicola Mascolo (127387), Maffia, P., Gianluca Grassia, Armando Ialenti, Antonio Parisi (127365), GRASSIA, GIANLUCA, Guglielmotti, A., IALENTI, ARMANDO, Grassia, G., IUVONE, TERESA, MASCOLO, NICOLA DOMENICO C. FERDINANDO, Carla Cicala (127370), Pasquale Maffia, MAIONE, FRANCESCO, Maione, F., Iuvone, T., Maddaluno, M., GUGLIELMOTTI A., Daniele De Filippis (127374), De Filippis, D., Antonio Parisi, Carla Cicala, Armando Ialenti (127390), Ialenti, A., Parisi, A., CICALA, CARLA, MAFFIA, PASQUALE, Marcella Maddaluno (127360), Marcella Maddaluno, Teresa Iuvone, PARISI A., Mascolo, N., Francesco Maione (127366), Di Lauro, M.V., Daniele De Filippis, DE FILIPPIS, DANIELE   +47 more
core   +1 more source

Construction of a MOF‐Based Snap‐Top Delivery Nanosystem for Powerful Dual‐Responsive Synergistic Colitis Treatment

Advanced Science, EarlyView.
A snap‐top delivery nanosystem based on an azobenzene metal–organic framework achieves targeted release of 6‐mercaptopurine via acid‐stable frameworks and hypoxia/pH dual‐responsive β‐cyclodextrin gates. This multifunctional platform integrates three synergistic mechanisms: precision drug delivery to inflammatory sites, intrinsic antioxidant properties
Xin Li, Miao Xu, Heran Li, Huan Jiang, Xin Wang, Lianjun Ma, Ying‐Wei Yang   +6 more
wiley   +1 more source

Monocyte Chemoattractant Protein 1 is a Prognostic Marker in ANCA-Associated Small Vessel Vasculitis

Mediators of Inflammation, 2009
Background. The (anti neutrophil cytoplasmatic autoantibody ANCA), associated small vessel vasculitides (ASVV) are relapsing-remitting inflammatory disorders, involving various organs, such as the kidneys.
Sophie Ohlsson, Omran Bakoush, Jan Tencer, Ole Torffvit, Mårten Segelmark   +4 more
doaj   +1 more source

Increased monocyte chemoattractant protein-1 levels indicating early vascular damage in lean young PCOS patients

, 2011
Serum levels of monocyte chemoattractant protein-1 and C-reactive protein levels, as early signs of vascular damage and cardiovascular disease, were increased in young, lean patients with polycystic ovary syndrome.
AKBIYIK, FİLİZ, Aytac, Rusen, Tolga Taşçı, Cem Somer Atabekoglu, ÖZMEN, BATUHAN, Aslı Yarcı, Murat Sönmezer, Ruşen Aytaç, Batuhan Özmen, TAŞÇI, TOLGA, Yarci, Asli, SÖNMEZER, MURAT, Filiz Akbıyık, ATABEKOĞLU, CEM SOMER   +13 more
core   +1 more source