Results 51 to 60 of about 130,905 (336)

Monocyte chemoattractant protein‐1 and coronary artery disease [PDF]

Clinical Cardiology, 2002
AbstractThe designation of atherosclerosis as a chronic inflammatory process represents an exciting and logical paradigm shift for cardiologists. Monocyte chemoattractant protein‐1 (MCP‐1) plays an important role in the recruitment and activation of monocytes and thus in the development of atherosclerosis. Enhanced MCP‐1 expression has been detected in
Uichi, Ikeda, Keiji, Matsui, Yoshiaki, Murakami, Kazuyuki, Shimada   +3 more
openaire   +2 more sources

Denervated Schwann cells attract macrophages by secretion of leukemia inhibitory factor (LIF) and monocyte chemoattractant protein-1 in a process regulated by interleukin-6 and LIF

, 2002
Injury to peripheral nerves results in the infiltration of immune cells, which remove axonal- and myelin-derived material. Schwann cells could play a key role in this process by regulating macrophage infiltration.
George K. Tofaris, Kristjan R. Jessen, Rhona Mirsky, Jessen, KR, Patterson, PH, Tofaris, GK, Mirsky, R, Paul H. Patterson   +7 more
core   +1 more source

Staphylococcus aureus regulates secretion of interleukin-6 and monocyte chemoattractant protein-1 through activation of nuclear factor kappaB signaling pathway in human osteoblasts

Brazilian Journal of Infectious Diseases
OBJECTIVE: Activation of nuclear factor kappaB by diverse bacteria regulates the secretion of chemokines and cytokines. Staphylococcus aureus (S.
Rende Ning, Xianlong Zhang, Xiaokui Guo, Qingtian Li   +3 more
doaj   +1 more source

Identifying chemokines as therapeutic targets in renal disease: Lessons from antagonist studies and knockout mice [PDF]

, 2004
Chemokines, in concert with cytokines and adhesion molecules, play multiple roles in local and systemic immune responses. In the kidney, the temporal and spatial expression of chemokines correlates with local renal damage and accumulation of chemokine ...
Anders, Hans-Joachim, Vielhauer, Volker, Eis, Vaclav, Schlöndorff, Detlef   +3 more
core   +1 more source

Human-induced pluripotent stem cell–derived neural stem cell exosomes improve blood–brain barrier function after intracerebral hemorrhage by activating astrocytes via PI3K/AKT/MCP-1 axis

Neural Regeneration Research
Cerebral edema caused by blood–brain barrier injury after intracerebral hemorrhage is an important factor leading to poor prognosis. Human-induced pluripotent stem cell–derived neural stem cell exosomes (hiPSC–NSC–Exos) have shown potential for brain ...
Conglin Wang, Fangyuan Cheng, Zhaoli Han, Bo Yan, Pan Liao, Zhenyu Yin, Xintong Ge, Dai Li, Rongrong Zhong, Qiang Liu, Fanglian Chen, Ping Lei   +11 more
doaj   +1 more source

Association between monocyte chemoattractant protein-1 and blood pressure in smokers

Journal of International Medical Research, 2018
Objective The expression level of monocyte chemoattractant protein-1 (MCP-1) is increased in atherosclerotic regions, inducing monocyte migration to the blood vessel wall.
Maki Komiyama, Rieko Takanabe, Koh Ono, Sayaka Shimada, Hiromichi Wada, Hajime Yamakage, Noriko Satoh-Asahara, Tatsuya Morimoto, Akira Shimatsu, Yuko Takahashi, Koji Hasegawa   +10 more
doaj   +1 more source

CCL2/Monocyte Chemoattractant Protein 1 and Parathyroid Hormone Action on Bone

Frontiers in Endocrinology, 2017
Chemokines are small molecules that play a crucial role as chemoattractants for several cell types, and their components are associated with host immune responses and repair mechanisms.
J. Siddiqui, N. Partridge
semanticscholar   +1 more source

Serum monocyte chemoattractant protein-1 is a biomarker in patients with diabetes and periodontitis

Indian Journal of Endocrinology and Metabolism, 2014
Introduction: The role of serum Monocyte Chemoattractant Protein-1 (MCP-1) as a biomarker of periodontitis is well documented; however, its role in diabetic patients with periodontitis is unknown.
Preethi Radhakrishnan, Padma Srikanth, Krishna G Seshadri, Ramya Barani, Maitreya Samanta   +4 more
doaj   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source