Results 41 to 50 of about 130,905 (336)

Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis

Hepatology, EarlyView., 2022
Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis. Abstract Background and Aims Nucleotide‐binding oligomerization domain‐like receptor‐family pyrin domain‐containing 3 (NLRP3) inflammasome activation has been shown to result in liver fibrosis.
Jana Knorr, Benedikt Kaufmann, Maria Eugenia Inzaugarat, Theresa Maria Holtmann, Lukas Geisler, Jana Hundertmark, Marlene Sophia Kohlhepp, Laela M. Boosheri, Daisy R. Chilin‐Fuentes, Amanda Birmingham, Kathleen M. Fisch, Joel D. Schilling, Sven H. Loosen, Christian Trautwein, Christoph Roderburg, Münevver Demir, Frank Tacke, Hal M. Hoffman, Ariel E. Feldstein, Alexander Wree   +19 more
wiley   +1 more source

Resistin Enhances Monocyte Chemoattractant Protein-1 Production in Human Synovial Fibroblasts and Facilitates Monocyte Migration

Cellular Physiology and Biochemistry, 2019
[[abstract]]BACKGROUND/AIMS: The adipocyte-secreting adipokine, resistin, may play a critical role in the modulation of inflammatory diseases. Migration and infiltration of mononuclear cells into inflammatory sites are critical events during the ...
Wei-Cheng Chen, Shih-Wei Wang, Chih-Yang Lin, Chun-Hao Tsai, Yi-Chin Fong, Ting-Yi Lin, Shun-Long Weng, Hsien-Da Huang, Kuang-Wen Liao, Chih-Hsin Tang   +9 more
doaj   +2 more sources

Induction of inflammatory angiogenesis by monocyte chemoattractant protein-1 [PDF]

International Journal of Cancer, 1999
Almost any growth of tumors is to some extent associated with an inflammatory reaction which may be anti-tumorigenic by acting directly on tumor cells or protumorigenic cells presumably by inducing tumor-associated angiogenesis. In this study, we have analyzed the angiogenesis-inducing capacity of monocyte chemoattractant protein-1 (MCP-1), a key ...
Goede, V., Brogelli, L., Ziche, Marina, Augustin, H. G.   +3 more
openaire   +3 more sources

P2Y6 receptor inhibition perturbs CCL2-evoked signalling in human monocytic and peripheral blood mononuclear cells [PDF]

, 2014
This work is supported the British Heart Foundation [grant number PG/13/22/ 30077]. Deposited in PMC for immediate release.The chemokine CCL2 serves to target circulating monocytes and other leukocytes to tissue during innate immune responses, and ...
Campwala, H., Fountain, Samuel J., Sexton, D. W., Campwala, Hinnah, Fountain, SJ, Crossman, David C., Sexton, Darren W., Campwala, H, Crossman, D. C., Fountain, S. J., Sexton, DW, Crossman, DC   +11 more
core   +1 more source

Мonocyte Chemoattractant Protein Levels in Patients with Primary Hypothyroidism

Mìžnarodnij Endokrinologìčnij Žurnal, 2016
Objective of the research — to study the content of monocyte chemoattractant protein‑1 (MCP‑1) in the urine of patients with primary hypothyroidism. Materials and methods. 141 patients with overt hypothyroidism have been examined. Among them, 71 patients
O.M. Didushko
doaj   +1 more source

Overexpression of Monocyte Chemoattractant Protein-1 in Adipose Tissues Causes Macrophage Recruitment and Insulin Resistance*

Journal of Biological Chemistry, 2006
Adipose tissue expression and circulating concentrations of monocyte chemoattractant protein-1 (MCP-1) correlate positively with adiposity. To ascertain the roles of MCP-1 overexpression in adipose, we generated transgenic mice by utilizing the adipocyte
Nozomu Kamei, K. Tobe, R. Suzuki, M. Ohsugi, Taku Watanabe, N. Kubota, Norie Ohtsuka-Kowatari, Katsuyoshi Kumagai, K. Sakamoto, Masatoshi Kobayashi, T. Yamauchi, K. Ueki, Y. Oishi, S. Nishimura, I. Manabe, H. Hashimoto, Y. Ohnishi, H. Ogata, K. Tokuyama, Masaki Tsunoda, T. Ide, K. Murakami, R. Nagai, T. Kadowaki   +23 more
semanticscholar   +1 more source

Circulating levels of monocyte chemoattractant protein‐1 as a potential measure of biological age in mice and frailty in humans

Aging Cell, 2017
A serum biomarker of biological versus chronological age would have significant impact on clinical care. It could be used to identify individuals at risk of early‐onset frailty or the multimorbidities associated with old age.
Matthew J. Yousefzadeh, M. Schafer, Nicole Noren Hooten, E. Atkinson, M. Evans, D. Baker, Ellen Quarles, P. Robbins, W. Ladiges, N. LeBrasseur, L. Niedernhofer   +10 more
semanticscholar   +1 more source

Circulating Monocyte Chemoattractant Protein-1 Levels and Lumbar Bone Mineral Density in Korean Women

Journal of Obesity & Metabolic Syndrome, 2017
Background : Monocyte chemoattractant protein-1 (MCP-1) is expressed in adipose tissue, macrophages, endothelial cells, and osteoblasts by parathyroid hormone administration.
Seong-Kyu Lee
doaj   +1 more source

Unravelling the Influence of Demographic and Lifestyle Factors on Monocyte Chemoattractant Protein-1 in Diabetic Retinopathy Patients

Journal of Bahria University Medical and Dental College, 2023
Objectives: To determine the association of Monocyte chemoattractant protein-1 (MCP-1) level with Age, blood glucose level, Exercise, Gender and Smoking in diabetic retinopathy patients. Study Design and settings: A case-control study was carried in the
Shabeer Ahmed, Hammad Raziq, Noman Sadiq, Sana Soomro, Rubina Amjad, Wazir Ahmed Baloch   +5 more
doaj   +1 more source

Evaluation of TGF-β1 and MCP-1 expression and tubulointerstitial fibrosis in children with Henoch-Schönlein purpura nephritis and IgA nephropathy: A clinical correlation

Clinics
OBJECTIVES: Henoch-Schönlein purpura nephritis and immunoglobulin A nephropathy are two diseases with similar clinical presentations but very different prognoses.
Zhao Shuiai, Shen Huijun, Gu Weizhong, Liu Aimin, Mao Jianhua   +4 more
doaj   +1 more source