Results 61 to 70 of about 317,992 (233)
Advanced Materials, EarlyView.An engineered Trojan Mycobacterium, developed via a “peeling‐off and masking‐up” strategy, functions as a powerful splenic myelopoiesis converter. This spleen‐targeted nanomedicine induces trained immunity to reprogram immunosuppressive myeloid reservoirs into antitumoral effectors.
Jin‐Ho Choi +5 more
wiley +1 more source
Percentage and concentration of circulating monocyte subsets.
, 2018 Percentage and concentration of circulating monocyte subsets.
Josep Lupón (294811) +12 more
core +1 more source
Advanced Materials for Biologics Delivery to Brain Tumors
Advanced Materials, EarlyView.Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng +4 more
wiley +1 more source
CD9+ B Cells Induce T Follicular Helper Cell Apoptosis to Regulate Germinal Center Regression
Advanced Science, EarlyView.A unique subset of CD9+ B cells regulates germinal center B (GC‐B) cell regression by inducing T follicular helper (Tfh) cell apoptosis through multiple signaling pathways, such as ALCAM‐CD6. FOXP1 plays a key role in GC‐B cell differentiation. These findings clarify mechanisms of GC degeneration and termination and offer potential targets for adenoid ...
Wenjing Liao +27 more
wiley +1 more source
Assessment of peripheral blood monocyte subsets by flow cytometry.
, 2018 In tube A, total monocyte population and frequency of the monocyte subsets was defined with CD86 (I) and CD14/CD16 (II) expression, respectively. In tube B, Perfect count beads (III) and monocytes (CD86+ cells) (IV) were selected to determine total ...
Josep Lupón (294811) +12 more
core +1 more source
Advanced Science, EarlyView.Pancreatic adenocarcinoma (PAAD) remains highly lethal with limited treatment options. This study demonstrates that coixenolide, a bioactive compound from Coix lacryma‐jobi L. and a key component of the clinically approved Kanglaite injection, exhibits enhanced antitumor efficacy in high‐fat diet (HFD)‐induced obese mice bearing PAAD tumors compared to
Kaidi Chen +20 more
wiley +1 more source
Inflammasome activation in bovine monocyte subsets.
, 2013 Analysis of inflammasome activation was done by measuring the secreted IL-1β in medium supernatants of monocyte subsets after combined stimulation with LPS and ATP. MACS-separated bovine monocyte subsets (n = 5 animals) were primed for 5 h with LPS (1 µg/
Peter Zieger (445437) +6 more
core +1 more source
Monocyte-related gene biomarkers for latent and active tuberculosis
, 2021 Monocytes are closely associated with tuberculosis (TB). Latent tuberculosis in some patients gradually develops into its active state. This study aimed to investigate the role of hub monocyte-associated genes in distinguishing latent TB infection (LTBI)
Jie He (132999) +2 more
core +1 more source
Mr BMT Achieves Systemic Macrophage Replacement With Preservation of Tissue Homeostasis
Advanced Science, EarlyView.Microglia replacement by bone marrow transplantation (Mr BMT) enables systemic replacement of tissue‐resident macrophages. Despite persistent macrophage and tissue remodeling across multiple organs, core biological functions and innate immune responses remain preserved, supporting long‐term maintenance of organismal homeostasis and the therapeutic ...
Yufei Xu +17 more
wiley +1 more source
Interdisciplinary Perspectives on Infectious Diseases, 2019 Background. Liver inflammation influences monocyte function, recruitment, and consequently inflammatory and fibrogenic responses. We aimed to investigate changes in the circulating monocyte phenotypes in response to Daclatasvir-Sofosbuvir (SOF/DCV ...
Hanan M. Fayed +2 more
doaj +1 more source