Results 131 to 140 of about 940,972 (387)

Phenotype and function of human monocytes remain mainly unaffected by very small superparamagnetic iron oxide particles

Frontiers in Nanotechnology
The field of medical application of organic or inorganic nanoparticles is extensive. Medical nanoparticles offer benefits but pose risks. For safe use in diagnostics and therapy, they should be inert, non-immunogenic, non-aggregating, and avoid long-term
Sari Hussein, Sari Hussein, Anja Andrea Kühl, Laura Golusda, Laura Golusda, Christina Plattner, Nadine Heinze, Nadine Heinze, Gregor Sturm, Christian Freise, Heike Traub, Mathias Schannor, Zlatko Trajanoski, Matthias Taupitz, Britta Siegmund, Daniela Paclik, Daniela Paclik   +16 more
doaj   +1 more source

CCR2 Signaling Promotes Brain Infiltration of Inflammatory Monocytes and Contributes to Neuropathology during Cryptococcal Meningoencephalitis

, 2021
Jintao Xu, Anutosh Ganguly, Jessica Zhao, Michel Ivey, Rafael Lopez, John J. Osterholzer, Clifford S. Cho, Michal A. Olszewski   +7 more
openalex   +1 more source

Microglial recruitment of IL-1β producing monocytes to brain endothelium causes stress-induced anxiety

Molecular Psychiatry, 2017
Psychosocial stress contributes to the development of anxiety and depression. Recent clinical studies have reported increased inflammatory leukocytes in circulation of individuals with stress-related psychiatric disorders.
D. Mckim, Michael D. Weber, A. Niraula, C. Sawicki, Xiaoyu Liu, B. Jarrett, Karol Ramirez-Chan, Yufen Wang, Rachel Roeth, Ana D. Sucaldito, Carly G. Sobol, N. Quan, J. Sheridan, J. Godbout   +13 more
semanticscholar   +1 more source

Host‐Directed Biomaterials for Combatting Bloodstream Infections: From Macrocyclic Peptides to Immune‐Activating Cell Backpacks

Advanced Functional Materials, EarlyView.
Bloodstream infections (BSI) are one of the leading causes of mortality and morbidity in both civilian and military populations. This paper summarizes recent progress in novel treatment strategies to manage BSI arising from both bacterial and fungal pathogens using molecules, particles, and materials to elicit host‐directed immunity.
Thomas Thomou, Jagadish Krishnappa, Justin B. Schaal, Prasad Tongaonkar, Dat Q. Tran, Wenchao Gu, Yung‐Fu Chang, Michael E. Selsted, Shaoyi Jiang, Samir Mitragotri, Michael Super, Christopher J. Bettinger   +11 more
wiley   +1 more source

Cell population data analysis for early diagnosis and prognosis of COVID-19: A Case-Control Study [PDF]

Medical Laboratory Journal
Background: Several hematological indicators have been linked to the intensity and course of Coronavirus Disease of 2019 (COVID-19), including platelets, total white blood cell (WBC) count, lymphocytes, neutrophils (as well as the neutrophil-lymphocyte ...
Priyadarshini Kumaraswamy Rajeswaran, Preethi Muthusamy Sundar, Prasanna Nedungadi Kumar, Karthikeyan Shanmugam   +3 more
doaj  

Evaluation of Lipid-Based Transfection in Primary Monocytes Within an Ex Vivo Whole-Blood Model

Biomolecules
Transfection is a fundamental method in biomedical research to study intracellular molecular mechanisms by manipulating target protein expression. Various methods have been developed to deliver nucleic acids into the cells of interest in vitro, with ...
Robin Moolan-Vadackumchery, Lan Zhang, Frank Stüber   +2 more
doaj   +1 more source

Succinate Promotes Phagocytosis of Monocytes/Macrophages in Teleost Fish

, 2021
Dai-xiao Yang, Hao Yang, Yunchao Cao, Ming Jiang, Jun Zheng, Bo Peng   +5 more
openalex   +1 more source

TLT-1 Promotes Platelet–Monocyte Aggregate Formation to Induce IL-10–Producing B Cells in Tuberculosis [PDF]

, 2022
Manni Wang, Xingyu Li, Qiaohua Wang, Mei Zhang, Jianzhong He, Siqi Ming, Ziqing Wang, Can Cao, Shun-Xian Zhang, Lanlan Geng, Sitang Gong, Xi Huang, Kang Chen, Yongjian Wu   +13 more
openalex   +1 more source

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

Advanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj, Hannah S. Newton, Jian Wang, Laxmi Pandey, Yelixza I. Avilla, Phong Nguyen, Morgan Chandler, Justin Halman, Yasmine Radwan, Stephanie Smith, Elijah Edmondson, Simone Difilippantonio, Chelsea Sanders, Bao Tran, Yongmei Zhao, Shaojun Xie, Edward Cedrone, Barry W. Neun, Meni Wanunu, Nikolay V. Dokholyan, Marina A. Dobrovolskaia, Kirill A. Afonin   +21 more
wiley   +1 more source

Characterization of avirulent mutant Legionella pneumophila that survive but do not multiply within human monocytes. [PDF]

, 1987
Legionella pneumophila, the causative agent of Legionnaires' disease, is a Gram-negative bacterium and a facultative intracellular parasite that multiplies in human monocytes and alveolar macrophages. In this paper, mutants of L.
Horwitz, MA
core