Results 11 to 20 of about 613,326 (371)
Toxins, 2020 Monocytes play an important role in both innate immunity and antigen presentation for specific cellular immune defense. In patients with chronic renal failure, as well as those treated with maintenance hemodialysis, these cells are largely dysregulated. There is a large body of literature on monocyte alterations in such patients.
Matthias Girndt +2 more
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The Monocyte That Wasn’t* [PDF]
Critical Care Medicine, 2015 This issue of Critical Care Medicine has a feature article entitled “Monocyte tumor necrosis factor-alpha converting enzyme catalytic activity and substrate shedding in sepsis and non-infectious systemic inflammation” (1). The authors eloquently demonstrate in a human translational study that monocyte tumor necrosis factor-alpha (TNF) converting enzyme
Philip A. Efron, Alicia M. Mohr
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Monocyte Heterogeneity: Consequences for Monocyte-Derived Immune Cells [PDF]
Journal of Immunology Research, 2016 Blood monocytes are precursors of dendritic cells, macrophages, and osteoclasts. They are a heterogeneous cell population with differences in size, phenotype, and function. Although monocytes maintain several tissue-specific populations of immune cells in homeostasis, their contribution to populations of dendritic cells, macrophages, and osteoclasts is
Sara Sprangers +2 more
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Journal of Experimental Medicine, 1991 In the present study we demonstrate that human monocytes activated by lipopolysaccharides (LPS) were able to produce high levels of interleukin 10 (IL-10), previously designated cytokine synthesis inhibitory factor (CSIF), in a dose dependent fashion. IL-
R. de Waal Malefyt +4 more
semanticscholar +1 more source
Antigen presentation by monocytes and monocyte-derived cells [PDF]
Current Opinion in Immunology, 2008 Monocytes are circulating mononuclear phagocytes with a fundamental capacity to differentiate into macrophages. This differentiation can, in the presence of the right environmental cues, be re-directed instead to dendritic cells (DCs). Recent advances have been made in understanding the role of monocytes and their derivatives in presenting antigen to ...
Claudia Jakubzick +2 more
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Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors
Science, 2017 What's in a drop of blood? Blood contains many types of cells, including many immune system components. Immune cells used to be characterized by marker-based assays, but now classification relies on the genes that cells express. Villani et al.
A. Villani +23 more
semanticscholar +1 more source
The Ontogeny of Monocyte Subsets [PDF]
Frontiers in Immunology, 2019 Classical and non-classical monocytes, and the macrophages and monocyte-derived dendritic cells they produce, play key roles in host defense against pathogens, immune regulation, tissue repair and many other processes throughout the body. Recent studies have revealed previously unappreciated heterogeneity among monocytes that may explain this ...
Anja A. Wolf +7 more
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EXPRESSION OF ADHESION MOLECULES ON PERIPHERAL BLOOD MONOCYTES DURING PREGNANCY
Медицинская иммунология, 2014 Peripheral blood monocytes play a key role in regulation of immune response during pregnancy. Intensive adhesion of monocytes to endothelium proves that monocytes are activated during pregnancy.
V. A. Mikhaylova +5 more
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Trained Immunity: An Overview and the Impact on COVID-19
Frontiers in Immunology, 2022 Effectively treating infectious diseases often requires a multi-step approach to target different components involved in disease pathogenesis. Similarly, the COVID-19 pandemic has become a global health crisis that requires a comprehensive understanding ...
Justin M. Brueggeman +12 more
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Evaluation of two different dendritic cell preparations with BCG reactivity [PDF]
Archives of Biological Sciences, 2016 Dendritic cells (DCs) play a key-role in the immune response against intracellular bacterial pathogens, including mycobacteria. Monocyte-derived dendritic cells (MoDCs) are considered to behave as inflammatory cell populations.
Fol Marek +7 more
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