Results 11 to 20 of about 940,972 (387)

CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis [PDF]

Nature, 2011
Macrophages abundantly found in the tumor microenvironment enhance malignancy(1). At metastatic sites a distinct population of metastasis associated macrophages (MAMs) promote tumor cell extravasation, seeding and persistent growth(2).
Bin-Zhi Qian, Takanori Kitamura, Jeffrey W Pollard   +2 more
exaly   +5 more sources

Granulocyte-Monocyte Progenitors and Monocyte-Dendritic Cell Progenitors Independently Produce Functionally Distinct Monocytes [PDF]

Immunity, 2017
Granulocyte-monocyte progenitors (GMPs) and monocyte-dendritic cell progenitors (MDPs) produce monocytes during homeostasis and in response to increased demand during infection. Both progenitor populations are thought to derive from common myeloid progenitors (CMPs), and a hierarchical relationship (CMP-GMP-MDP-monocyte) is presumed to underlie ...
Yáñez Boyer, Alberto, Coetzee, S.G., Olsson, A., Muench, D.E., Berman, B.P., Hazelett, D.J., Salomonis, Nathan, Grimes, H.L., Goodridge, Helen S.   +8 more
openaire   +5 more sources

Monocyte adaptations in patients with obesity during a 1.5 year lifestyle intervention

Frontiers in Immunology, 2022
BackgroundObesity is associated with chronic, low-grade inflammation, which is reflected in altered peripheral blood monocyte characteristics. The aim of this study was to analyze the monocyte subset composition (classical (CM), intermediate (IM) and non-
Eline S. van der Valk, Eline S. van der Valk, Daniël S. Mulder, Daniël S. Mulder, Tessa Kouwenhoven, Tessa Kouwenhoven, Nicole M. A. Nagtzaam, Elisabeth F. C. van Rossum, Willem A. Dik, Pieter J. M. Leenen   +9 more
doaj   +1 more source

The slan antigen identifies the prototypical non-classical CD16+-monocytes in human blood

Frontiers in Immunology, 2023
IntroductionPeripheral monocytes in humans are conventionally divided into classical (CL, CD14++CD16−), intermediate (INT, CD14++CD16+) and non-classical (NC, CD14dim/−CD16++) cells, based on their expression levels of CD14 and CD16.
Nicola Tamassia, Francisco Bianchetto-Aguilera, Sara Gasperini, Alessio Grimaldi, Alessio Grimaldi, Claudia Montaldo, Federica Calzetti, Elisa Gardiman, Ilaria Signoretto, Monica Castellucci, Vincenzo Barnaba, Marco Tripodi, Marco Antonio Cassatella   +12 more
doaj   +1 more source

Nucleocapsid and Spike Proteins of the Coronavirus SARS-CoV-2 Induce IL6 in Monocytes and Macrophages—Potential Implications for Cytokine Storm Syndrome

Vaccines, 2021
The pandemic of the new coronavirus SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) has led to the deaths of more than 1.5 million people worldwide.
Iwona Karwaciak, Anna Sałkowska, Kaja Karaś, Jarosław Dastych, Marcin Ratajewski   +4 more
doaj   +1 more source

Monocyte Heterogeneity: Consequences for Monocyte-Derived Immune Cells [PDF]

Journal of Immunology Research, 2016
Blood monocytes are precursors of dendritic cells, macrophages, and osteoclasts. They are a heterogeneous cell population with differences in size, phenotype, and function. Although monocytes maintain several tissue-specific populations of immune cells in homeostasis, their contribution to populations of dendritic cells, macrophages, and osteoclasts is
Sara Sprangers, Teun J. de Vries, Vincent Everts   +2 more
openaire   +6 more sources

SARS-CoV-2 engages inflammasome and pyroptosis in human primary monocytes

Cell Death Discovery, 2021
Infection by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been associated with leukopenia and uncontrolled inflammatory response in critically ill patients.
André C. Ferreira, V. C. Soares, Isaclaudia G. de Azevedo-Quintanilha, S. S. Dias, N. Fintelman-Rodrigues, Carolina Q. Sacramento, Mayara Mattos, Caroline S. de Freitas, J. Temerozo, Lívia Teixeira, Eugenio Damaceno Hottz, Ester A. Barreto, Camila R. R. Pão, Lohanna Palhinha, M. Miranda, D. Bou-Habib, F. Bozza, P. Bozza, T. M. Souza   +18 more
semanticscholar   +1 more source

Expansion of inflammatory monocytes in periphery and infiltrated into thyroid tissue in Graves’ disease

Scientific Reports, 2021
Monocytes are important mediators of immune system and are reported to be altered in autoimmune disorders. Little is known about the pathological role of monocytes in Graves’ disease (GD).
Xinxin Chen, Yanqiu Wang, Yicheng Qi, Jiqi Yan, Fengjiao Huang, Mengxi Zhou, Weiqing Wang, Guang Ning, Yulin Zhou, Shu Wang   +9 more
doaj   +1 more source

Pathogenic T-cells and inflammatory monocytes incite inflammatory storms in severe COVID-19 patients

National Science Review, 2020
Pathogenic human coronavirus infections, such as severe acute respiratory syndrome CoV (SARS-CoV) and Middle East respiratory syndrome CoV (MERS-CoV), cause high morbidity and mortality1, 2 Recently, a severe pneumonia-associated respiratory syndrome ...
Yonggang Zhou, Binqing Fu, Xiaohu Zheng, Dongsheng Wang, Changcheng Zhao, Yingjie Qi, R. Sun, Z. Tian, Xiaoling Xu, Haiming Wei   +9 more
semanticscholar   +1 more source

Monocytes and Macrophages in COVID-19

Frontiers in Immunology, 2021
COVID-19 is a contagious viral disease caused by SARS-CoV-2 that led to an ongoing pandemic with massive global health and socioeconomic consequences.
Rainer Knoll, J. Schultze, J. Schulte-Schrepping   +2 more
semanticscholar   +1 more source