Results 21 to 30 of about 102,629 (199)

The Flow Cytometry Study of Cellular Immunity in Rhesus Monkeys after Experimental Infection with SARS CoV 2 Virus

Проблемы особо опасных инфекций, 2022
Cellular immunity plays an important role in the pathogenesis and formation of protective immune defense against the SARS‑CoV‑2 virus.The aim of the work was to study the cellular immunity of rhesus monkeys applying flow cytometry after experimental ...
G. V. Borisevich, S. L. Kirillova, I. V. Shatokhina, V. N. Lebedev, S. S. Solov’ev, S. I. Syromyatnikova, N. V. Shagarova, N. V. Boyarskaya, N. G. Levkovich, D. A. Solyanik, A. F. Andrus, V. V. Rubtsov, V. T. Krotkov, V. S. Kulish, I. V. Surovyatkina, V. B. Kirillov, A. V. Koval’chuk, V. B. Pantyukhov, D. A. Kutaev, S. V. Borisevich   +19 more
doaj   +1 more source

Monocytes/macrophages express CCR9 in rheumatoid arthritis and CCL25 stimulates their differentiation [PDF]

, 2010
Introduction: Monocytes/macrophages accumulate in the rheumatoid (RA) synovium where they play a central role in inflammation and joint destruction. Identification of molecules involved in their accumulation and differentiation is important to inform ...
Buckley, Christopher, Helen Williams, Cartwright, A, John HH Williams, Andrew Filer, Schmutz, Caroline, Oliver Haworth, Filer, Andrew, Mike Salmon, Haworth, O, Buckley, Christopher D., Alison Cartwright, Christopher D Buckley, Schmutz, C, Williams, John H. H., Middleton, J, Haworth, Oliver, Buckley, CD, Williams, JH, Cartwright, Alison, Caroline Schmutz, Williams, HJ, Middleton, Jim F., Williams, Helen, Salmon, Mike, Filer, A, Salmon, M, Williams, J, Williams, H, Middleton, Jim F S, Jim Middleton   +30 more
core   +1 more source

Can Hematological Parameters be Used for Differential Diagnosis in Rotavirus Infection at any Age of Children? A 6-year Outcomes from a Tertiary Referral Center

Haseki Tıp Bülteni, 2021
Aim:Routine blood parameters are widely used to detect of infectious diseases. Our study aimed to investigate the hematological parameters changes in rotavirus (RV) acute gastroenteritis and to evaluate the value of these parameters in children.Methods ...
Meliha Aksoy Okan, Hayrettin Temel, Mesut Okur, Ayse Istanbullu Tosun   +3 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Interleukin-10 disrupts liver repair in acetaminophen-induced acute liver failure

Frontiers in Immunology, 2023
IntroductionSystemic levels of the anti-inflammatory cytokine interleukin 10 (IL-10) are highest in acetaminophen (APAP)-induced acute liver failure (ALF) patients with the poorest prognosis. The mechanistic basis for this counterintuitive finding is not
Katherine Roth, Katherine Roth, Katherine Roth, Katherine Roth, Jenna Strickland, Jenna Strickland, Jenna Strickland, Jenna Strickland, Asmita Pant, Robert Freeborn, Robert Freeborn, Rebekah Kennedy, Rebekah Kennedy, Cheryl E. Rockwell, Cheryl E. Rockwell, Cheryl E. Rockwell, Cheryl E. Rockwell, James P. Luyendyk, James P. Luyendyk, Bryan L. Copple, Bryan L. Copple, Bryan L. Copple, Bryan L. Copple   +22 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Quantitative whole-cell MALDI-TOF MS fingerprints distinguishes human monocyte sub-populations activated by distinct microbial ligands [PDF]

, 2015
Conventionally, human monocyte sub-populations are classified according to surface marker expression into classical (CD14(++)CD16(-)), intermediate (CD14(++)CD16(+)) and non-classical (CD14(+)CD16(++)) lineages. The involvement of non-classical monocytes,
Brunisholz, René, Vogel, Guido, Daubenberger, Claudia, Patricia Otieno, René Brunisholz, Pflüger, Valentin, Portevin, Damien, Valentin Pflüger, Otieno, Patricia, Damien Portevin, Claudia Daubenberger, Guido Vogel   +11 more
core   +1 more source

Osteoclast responses to metal ions [PDF]

, 2009
Màster Oficial en Enginyeria BiomèdicaCentral model of the study will be the osteoclast culture on dentin. Osteoclast development from monocytes will be followed biochemically and histologically.
Prehn Gallo, Ricardo
core   +6 more sources

TLRs1-10 Protein Expression in Circulating Human White Blood Cells during Bacterial and COVID-19 Infections

Journal of Innate Immunity
Introduction: Toll-like receptors play crucial roles in the sepsis-induced systemic inflammatory response. Septic shock mortality correlates with overexpression of neutrophilic TLR2 and TLR9, while the role of TLR4 overexpression remains a debate.
Louise Chomel, Mathieu Vogt, Julien Demiselle, Pierrick Le Borgne, Marine Tschirhart, Valentin Morandeau, Hamid Merdji, Laurent Miguet, Julie Helms, Ferhat Meziani, Laurent Mauvieux   +10 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source