Results 21 to 30 of about 467,774 (259)

Examination of the inflammatory nature of different placental syncytiotrophoblast microparticles (STBM) preparations on human monocytes [PDF]

, 2009
Background: Healthy human pregnancies are accompanied by a mild systemic maternal inflammatory response, which includes activation of peripheral blood monocytes.
Messerli, Marianne Simone
core   +1 more source

The Ontogeny of Monocyte Subsets [PDF]

Frontiers in Immunology, 2019
Classical and non-classical monocytes, and the macrophages and monocyte-derived dendritic cells they produce, play key roles in host defense against pathogens, immune regulation, tissue repair and many other processes throughout the body. Recent studies have revealed previously unappreciated heterogeneity among monocytes that may explain this ...
Anja A. Wolf, Anja A. Wolf, Alberto Yáñez, Alberto Yáñez, Pijus K. Barman, Pijus K. Barman, Helen S. Goodridge, Helen S. Goodridge   +7 more
openaire   +4 more sources

Influenza virus A infection of human monocyte and macrophage subpopulations reveals increased susceptibility associated with cell differentiation [PDF]

, 2012
Influenza virus infection accounts for significant morbidity and mortality world-wide. Interactions of the virus with host cells, particularly those of the macrophage lineage, are thought to contribute to various pathological changes associated with poor
Jackson David, Richard E. Randall, Richard E. Randall (190211), Nash, A.A., Anthony A Nash, Hoeve, M.A., Marieke A Hoeve, Anthony A. Nash, Hoeve Marieke A., Nash, Anthony A., Dransfield, I., Marieke A. Hoeve (190207), David Jackson (84936), Richard E Randall, Randall Richard E., Jackson, David, Randall, R.E., Nash Anthony A., David Jackson, Jackson, D., Ian Dransfield (190213), Dransfield, Ian, Marieke A. Hoeve, Anthony A. Nash (190209), Randall, Richard E., Ian Dransfield, Hoeve, Marieke A., Dransfield Ian   +27 more
core   +1 more source

Restriction of HIV-1 replication in monocytes is abolished by Vpx of SIVsmmPBj

, 2009
Background: Human primary monocytes are refractory to infection with the human immunodeficiency virus 1 (HIV-1) or transduction with HIV-1-derived vectors.
Kaiser, Julia, Schüle Silke, Wolfrum, Nina, Heidmeier Sabine, Sylvia Panitz, Julia K Kaiser, Panitz Sylvia, Klaus Cichutek, Silke Schüle, Heidmeier, Sabine, Kaiser Julia K., Schweizer, Matthias, Cichutek Klaus, Schüle, Silke, Kloke, Björn-Philipp, Matthias Schweizer, Wolfrum Nina, Panitz, Sylvia, Sabine Heidmeier, Cichutek, Klaus, Nina Wolfrum, Kloke Björn-Philipp, Schweizer Matthias, Björn-Philipp Kloke   +23 more
core   +1 more source

Macrophage-derived human resistin is induced in multiple helminth infections and promotes inflammatory monocytes and increased parasite burden. [PDF]

, 2015
Parasitic helminth infections can be associated with lifelong morbidity such as immune-mediated organ failure. A better understanding of the host immune response to helminths could provide new avenues to promote parasite clearance and/or alleviate ...
Josiah I. Chung, Nutman, Thomas B, Barnes, MA, Josiah I Chung, Chung, Josiah I, Cooper, Philip J, Meera G. Nair (285902), Josiah I. Chung (682394), Nair, Meera G, Gang Chen (107840), Thomas B. Nutman, Nair, MG, Mali Camberis, Le Gros, G, Graham Le Gros, Mark A. Barnes (682393), Thomas B. Nutman (113195), Le Gros, Graham, Steel, C, Mark A Barnes, Jessica C. Jang (682391), Mitchell A. Lazar, Camberis, M, Thomas B Nutman, Meera G. Nair, Cathy Steel (180788), Jang, JC, Meera G Nair, Graham Le Gros (682396), Cooper, PJ, Jessica C Jang, Spencer H. Wang, Lazar, MA, Mitchell A Lazar, Spencer H. Wang (682392), Lazar, Mitchell A, Mark A. Barnes, Chen, Gang, Camberis, Mali, Mitchell A. Lazar (27888), Wang, SH, Gang Chen, Barnes, Mark A, Chen, G, Spencer H Wang, Philip J. Cooper, Wang, Spencer H, Mali Camberis (682395), Philip J. Cooper (218309), Chung, JI, Nutman, TB, Cathy Steel, Jang, Jessica C, Philip J Cooper, Steel, Cathy, Jessica C. Jang   +55 more
core   +1 more source

Monocyte and Haemostasis

Hematology, 1998
Human monocytes may play a central role in haemostasis since they are the only circulating blood cells capable to express tissue factor (TF) and therefore trigger the extrinsic pathway of coagulation. The aim of this review is to illustrate that monocytes also participate in haemostasis independently of TF expression.
M, Broussas, P, Cornillet-Lefebvre, G, Potron, P, Nguyen   +3 more
openaire   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Monocytes in the Rat

Immunobiology, 2000
We review our methods for definition and phenotypical characterisation of normal and activated rat monocytes. To obtain a comprehensive sample of all blood monocytes including cells from the marginal pool of the blood stream, we extensively perfuse the extrapulmonary circulation with cold PBS/EDTA.
V, Grau, A, Scriba, O, Stehling, B, Steiniger   +3 more
openaire   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, Volume 20, Issue 6, Page 1398-1419, June 2026.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Classical monocytes from patients with pancreatic ductal adenocarcinoma exhibit a significantly altered transcriptome profile compared with healthy volunteers [PDF]

, 2014
The copyright of this thesis rests with the author and no quotation from it or information derived from it may be published without the prior written consent of the authorPancreatic Ductal Adenocarcinoma (PDAC) affects approximately 8000 people every ...
Cook, Jenny Anne
core