Mechanism-based model characterizing bidirectional interaction between PEGylated liposomal CKD-602 (S-CKD602) and monocytes in cancer patients [PDF]
, 2012 S-CKD602 is a PEGylated liposomal formulation of CKD-602, a potent topoisomerase I inhibitor. The objective of this study was to characterize the bidirectional pharmacokinetic-pharmacodynamic (PK-PD) interaction between S-CKD602 and monocytes.
Bang YJ +12 more
core +2 more sources
EXPRESSION OF ADHESION MOLECULES ON PERIPHERAL BLOOD MONOCYTES DURING PREGNANCY
Медицинская иммунология, 2014 Peripheral blood monocytes play a key role in regulation of immune response during pregnancy. Intensive adhesion of monocytes to endothelium proves that monocytes are activated during pregnancy.
V. A. Mikhaylova +5 more
doaj +1 more source
Histamine and Histamine H4 Receptor Promotes Osteoclastogenesis in Rheumatoid Arthritis. [PDF]
, 2017 Histamine H4 receptor (H4R) has immune-modulatory and chemotaxic effects in various immune cells. This study aimed to determine the osteoclastogenic role of H4R in rheumatoid arthritis (RA).
Firestein, Gary S +5 more
core +1 more source
Percutaneous transluminal angioplasty in patients with peripheral arterial disease does not affect circulating monocyte subpopulations [PDF]
, 2016 Monocytes are mononuclear cells characterized by distinct morphology and expression of CD14 and CD16 surface receptors. Classical, quiescent monocytes are positive for CD14 (lipopolysaccharide receptor) but do not express Fc gamma receptor III (CD16 ...
Krzanowski, Marek +5 more
core +5 more sources
THE PHENOTYPE AND FUNCTION OF MONOCYTES IN PATIENTS WITH PULMONARY TUBERCULOSIS
Медицинская иммунология, 2014 . Peripheral blood monocytes were investigated in the patients with pulmonary tuberculosis. It was established that population of CD14+16+ monocytes was twofold increased in the patients with tuberculosis.
L. V. Sakhno +8 more
doaj +1 more source
Exosomal αvβ6 integrin is required for monocyte M2 polarization in prostate cancer [PDF]
, 2018 Therapeutic approaches aimed at curing prostate cancer are only partially successful given the occurrence of highly metastatic resistant phenotypes that frequently develop in response to therapies.
Altieri, Dario C. +23 more
core +1 more source
Umbilical Cord Blood-Derived Monocytes as A Reliable Source of Functional Macrophages for Biomedical Research [PDF]
Cell Journal, 2023 Objective: Macrophages are multifunctional immune cells widely used in immunological research. While autologousmacrophages have been widely used in several biomedical applications, allogeneic macrophages have alsodemonstrated similar or even superior ...
Shukoofeh Torabi +7 more
doaj +1 more source
Persistent Infiltration and Impaired Response of Peripherally-Derived Monocytes after Traumatic Brain Injury in the Aged Brain. [PDF]
, 2018 Traumatic brain injury (TBI) is a leading cause for neurological disabilities world-wide. TBI occurs most frequently among the elderly population, and elderly TBI survivors suffer from reduced recovery and poorer quality of life. The effect of age on the
Chou, Austin +4 more
core +3 more sources
Nanomaterials, 2021 The evaluation of carbon-based nanomaterials’ (C-BNMs’) interactions with the immune system, notably their ability to cause inflammation, is a critical step in C-BNM health risk assessment. Particular attention should be given to those C-BNMs that do not
Tereza Svadlakova +11 more
doaj +1 more source
Monocytes regulate the mechanism of T-cell death by inducing Fas-mediated apoptosis during bacterial infection. [PDF]
, 2012 Monocytes and T-cells are critical to the host response to acute bacterial infection but monocytes are primarily viewed as amplifying the inflammatory signal.
A Kadioglu +64 more
core +4 more sources