Results 11 to 20 of about 737,831 (351)

Monocyte adaptations in patients with obesity during a 1.5 year lifestyle intervention

Frontiers in Immunology, 2022
BackgroundObesity is associated with chronic, low-grade inflammation, which is reflected in altered peripheral blood monocyte characteristics. The aim of this study was to analyze the monocyte subset composition (classical (CM), intermediate (IM) and non-
Eline S. van der Valk, Eline S. van der Valk, Daniël S. Mulder, Daniël S. Mulder, Tessa Kouwenhoven, Tessa Kouwenhoven, Nicole M. A. Nagtzaam, Elisabeth F. C. van Rossum, Willem A. Dik, Pieter J. M. Leenen   +9 more
doaj   +1 more source

The slan antigen identifies the prototypical non-classical CD16+-monocytes in human blood

Frontiers in Immunology, 2023
IntroductionPeripheral monocytes in humans are conventionally divided into classical (CL, CD14++CD16−), intermediate (INT, CD14++CD16+) and non-classical (NC, CD14dim/−CD16++) cells, based on their expression levels of CD14 and CD16.
Nicola Tamassia, Francisco Bianchetto-Aguilera, Sara Gasperini, Alessio Grimaldi, Alessio Grimaldi, Claudia Montaldo, Federica Calzetti, Elisa Gardiman, Ilaria Signoretto, Monica Castellucci, Vincenzo Barnaba, Marco Tripodi, Marco Antonio Cassatella   +12 more
doaj   +1 more source

Nucleocapsid and Spike Proteins of the Coronavirus SARS-CoV-2 Induce IL6 in Monocytes and Macrophages—Potential Implications for Cytokine Storm Syndrome

Vaccines, 2021
The pandemic of the new coronavirus SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) has led to the deaths of more than 1.5 million people worldwide.
Iwona Karwaciak, Anna Sałkowska, Kaja Karaś, Jarosław Dastych, Marcin Ratajewski   +4 more
doaj   +1 more source

Restriction of HIV-1 replication in monocytes is abolished by Vpx of SIVsmmPBj [PDF]

, 2009
Background: Human primary monocytes are refractory to infection with the human immunodeficiency virus 1 (HIV-1) or transduction with HIV-1-derived vectors.
Silke Schüle, Björn-Philipp Kloke, Julia K. Kaiser, Sabine Heidmeier, Sylvia Panitz, Nina Wolfrum, Klaus Cichutek, Matthias Schweizer, Reuben S. Harris, S Neil, S Sonza, MD Mühlebach, S Sonza, K Triques, G Peng, V Arfi, YL Chiu, PJ Ellery, M Pion, N Wolfrum, TM Fletcher 3rd, C Goujon, C Goujon, R Sleigh, S Mahalingam, LA Mahnke, HA Pancio, H Schuitemaker, T Kino, P Di Marzio, L Selig, L Jarrosson-Wuilleme, JA Poole, VM Hirsch, JA LaBonte, K Lee, B Song, M Stremlau, R Mariani, G Brennan, A Gruber, PH Tan, M Belshan, PK Singhal, C Goujon, N Sharova, C Dong, LY Liou, G Peng, Y Iwatani, JC Kappes, G Berger, R Sakuma, R Sakuma, M Stremlau, J Shi, E Sokolskaja, PK Singhal, R Sakuma, L Naldini, PM Strappe, DS Ory   +61 more
core   +6 more sources

Monocyte Heterogeneity: Consequences for Monocyte-Derived Immune Cells [PDF]

Journal of Immunology Research, 2016
Blood monocytes are precursors of dendritic cells, macrophages, and osteoclasts. They are a heterogeneous cell population with differences in size, phenotype, and function. Although monocytes maintain several tissue-specific populations of immune cells in homeostasis, their contribution to populations of dendritic cells, macrophages, and osteoclasts is
Sara Sprangers, Teun J. de Vries, Vincent Everts   +2 more
openaire   +6 more sources

Calcium-sensing receptor-mediated NLRP3 inflammasome activation in rheumatoid arthritis and autoinflammation

Frontiers in Physiology, 2023
The calcium-sensing receptor (CaSR) is expressed in many cell types – including immune cells and in particular circulating monocytes. Here, the receptor plays an important physiological role as a regulator of constitutive macropinocytosis.
Lina Emilia Werner, Ulf Wagner
doaj   +1 more source

Manufacturing Dendritic Cells for Immunotherapy: Monocyte Enrichment [PDF]

, 2020
Dendritic cells play a key role in activation of the immune system as potent antigen-presenting cells. This pivotal position, along with the ability to generate dendritic cells from monocytes and ready uptake of antigen, makes them an intriguing vehicle ...
Cox, Cheryl, Hopewell, Emily L.
core   +1 more source

Epstein-Barr virus lytic infection promotes activation of Toll-like receptor 8 innate immune response in systemic sclerosis monocytes [PDF]

, 2017
BACKGROUND: Monocytes/macrophages are activated in several autoimmune diseases, including systemic sclerosis (scleroderma; SSc), with increased expression of interferon (IFN)-regulatory genes and inflammatory cytokines, suggesting dysregulation of the ...
Dreyfus, David H., FAGGIONI, Alberto, FARINA, Antonella, Farina, G. Alessandra, Lacconi, Valentina, Lenna, Stefania, MORRONE, Stefania, PERUZZI, Giovanna, QUARTA, SILVIA, ROSATO, Edoardo, Trojanowska, Maria, VESTRI, Anna Rita, York, Michael   +12 more
core   +1 more source

A novel myeloid cell in murine spleen defined through gene profiling [PDF]

, 2019
A novel myeloid antigen presenting cell can be generated through in vitro haematopoiesis in long-term splenic stromal cocultures. The in vivo equivalent subset was recently identified as phenotypically and functionally distinct from the spleen subsets of
Dabiri GA, Ghosh S, Helen C. O’Neill, Schiopu A, Terence J. O’Neill, Ying‐Ying Hey   +5 more
core   +1 more source

Celiac Disease Monocytes Induce a Barrier Defect in Intestinal Epithelial Cells [PDF]

, 2019
Intestinal epithelial barrier function in celiac disease (CeD) patients is altered. However, the mechanism underlying this effect is not fully understood.
Branchi, Federica, Cardoso-Silva, Danielle, Delbue, Deborah, Itzlinger, Alice, Letizia, Marilena, Schumann, Michael, Siegmund, Britta   +6 more
core   +1 more source