Results 11 to 20 of about 419,171 (259)

Monocytes in Uremia [PDF]

Toxins, 2020
Monocytes play an important role in both innate immunity and antigen presentation for specific cellular immune defense. In patients with chronic renal failure, as well as those treated with maintenance hemodialysis, these cells are largely dysregulated. There is a large body of literature on monocyte alterations in such patients.
Matthias Girndt, Bogusz Trojanowicz, Christof Ulrich   +2 more
openaire   +4 more sources

The Monocyte That Wasn’t* [PDF]

Critical Care Medicine, 2015
This issue of Critical Care Medicine has a feature article entitled “Monocyte tumor necrosis factor-alpha converting enzyme catalytic activity and substrate shedding in sepsis and non-infectious systemic inflammation” (1). The authors eloquently demonstrate in a human translational study that monocyte tumor necrosis factor-alpha (TNF) converting enzyme
Philip A, Efron, Alicia M, Mohr
openaire   +2 more sources

Antigen presentation by monocytes and monocyte-derived cells [PDF]

Current Opinion in Immunology, 2008
Monocytes are circulating mononuclear phagocytes with a fundamental capacity to differentiate into macrophages. This differentiation can, in the presence of the right environmental cues, be re-directed instead to dendritic cells (DCs). Recent advances have been made in understanding the role of monocytes and their derivatives in presenting antigen to ...
Gwendalyn J, Randolph, Claudia, Jakubzick, Chunfeng, Qu   +2 more
openaire   +2 more sources

Monocyte Heterogeneity: Consequences for Monocyte-Derived Immune Cells [PDF]

Journal of Immunology Research, 2016
Blood monocytes are precursors of dendritic cells, macrophages, and osteoclasts. They are a heterogeneous cell population with differences in size, phenotype, and function. Although monocytes maintain several tissue-specific populations of immune cells in homeostasis, their contribution to populations of dendritic cells, macrophages, and osteoclasts is
Sara Sprangers, Teun J. de Vries, Vincent Everts   +2 more
openaire   +6 more sources

Glycolysis Is Required for LPS-Induced Activation and Adhesion of Human CD14+CD16− Monocytes

Frontiers in Immunology, 2019
Monocytes in humans consist of 3 subsets; CD14+CD16− (classical), CD14+CD16+ (intermediate) and CD14dimCD16+ (non-classical), which exhibit distinct and heterogeneous responses to activation.
Man K. S. Lee, Man K. S. Lee, Annas Al-Sharea, Annas Al-Sharea, Waled A. Shihata, Camilla Bertuzzo Veiga, Olivia D. Cooney, Andrew J. Fleetwood, Andrew J. Fleetwood, Michelle C. Flynn, Ellen Claeson, Clovis S. Palmer, Graeme I. Lancaster, Darren C. Henstridge, John A. Hamilton, John A. Hamilton, Andrew J. Murphy   +16 more
doaj   +1 more source

The Ontogeny of Monocyte Subsets [PDF]

Frontiers in Immunology, 2019
Classical and non-classical monocytes, and the macrophages and monocyte-derived dendritic cells they produce, play key roles in host defense against pathogens, immune regulation, tissue repair and many other processes throughout the body. Recent studies have revealed previously unappreciated heterogeneity among monocytes that may explain this ...
Anja A. Wolf, Anja A. Wolf, Alberto Yáñez, Alberto Yáñez, Pijus K. Barman, Pijus K. Barman, Helen S. Goodridge, Helen S. Goodridge   +7 more
openaire   +4 more sources

Immunophenotyping of circulating mononuclear cells in active pulmonary tuberculosis

Journal of Infection in Developing Countries, 2018
Introduction: Interpreting the interactions between M. tuberculosis and the host innate and adaptive immune defense mechanisms is mandatory for understanding the pathogenesis of active pulmonary TB (APTB).
Amany Elkholy, Mirvat El Anany, Ghada Mohamed Ezzat, Fadwa Abd El Reheem, Assem Fouad Elessawy   +4 more
doaj   +1 more source

OPPORTUNITIES OF FLOW CYTOMETRY IN DIAGNOSTICS OF INFECTIOUS DISEASES. PART 1

Инфекция и иммунитет, 2014
. Development of a modern medical science demands more thorough and deeper approach to diagnostics of diseases. New diagnostic technologies for these investigations are necessary and flow cytometry is such technology.
S. V. Khaidukov, A. V. Zurochka
doaj   +1 more source

Disharmonic Inflammatory Signatures in COVID-19: Augmented Neutrophils’ but Impaired Monocytes’ and Dendritic Cells’ Responsiveness

Cells, 2020
COVID-19, caused by SARS-CoV-2 virus, emerged as a pandemic disease posing a severe threat to global health. To date, sporadic studies have demonstrated that innate immune mechanisms, specifically neutrophilia, NETosis, and neutrophil-associated cytokine
Zuzana Parackova, Irena Zentsova, Marketa Bloomfield, Petra Vrabcova, Jitka Smetanova, Adam Klocperk, Grigorij Mesežnikov, Luis Fernando Casas Mendez, Tomas Vymazal, Anna Sediva   +9 more
doaj   +1 more source

Increasing the Magnesium Concentration in Various Dialysate Solutions Differentially Modulates Oxidative Stress in a Human Monocyte Cell Line

Antioxidants, 2020
Oxidative stress is exacerbated in hemodialysis patients by several factors, including the uremic environment and the use of dialysis fluids (DFs). Since magnesium (Mg) plays a key role in modulating immune function and in reducing oxidative stress, we ...
Carmen Vida, Julia Carracedo, Patricia de Sequera, Guillermo Bodega, Rafael Pérez, Matilde Alique, Rafael Ramírez   +6 more
doaj   +1 more source