Results 21 to 30 of about 613,326 (371)

Chronic monocytic leukemia with transformation into acute monocytic leukemia

Medicni perspektivi (Medical perspectives), 2021
Chronic myelomonocytic leukosis (CMML) is rarely diagnosed and amounts to 1 per 100 thousand of adults per year, more often in men over 60 years.  The clinical case of the rare, prolonged course of myelodysplastic chronic myelomonocytic leukosis (MD-CMML) in a middle-aged woman with rapid transformation into acute monocytic leukemia (AMoL-M5в) with the
Shponka I.S., Pesotskaya L.A., Korolenko H.S., Hutnik I.O., Murashevych B.V., Nikonenko V.A.   +5 more
openaire   +5 more sources

VCAM1/VLA4 interaction mediates Ly6Clow monocyte recruitment to the brain in a TNFR signaling dependent manner during fungal infection.

PLoS Pathogens, 2020
Monocytes exist in two major populations, termed Ly6Chi and Ly6Clow monocytes. Compared to Ly6Chi monocytes, less is known about Ly6Clow monocyte recruitment and mechanisms involved in the recruitment of this subset.
Donglei Sun, Mingshun Zhang, Peng Sun, Gongguan Liu, Ashley B Strickland, Yanli Chen, Yong Fu, Mohammed Yosri, Meiqing Shi   +8 more
doaj   +1 more source

Development of Monocytes, Macrophages, and Dendritic Cells

Science, 2010
Development of Myeloid Immune Cells As leukocytes develop to maturity, they proceed through an array of phenotypically distinct intermediates. For T and B lymphocyte populations, the different developmental stages, anatomical locations, and cell signals ...
F. Geissmann, M. Manz, Steffen Jung, M. Sieweke, M. Merad, K. Ley   +5 more
semanticscholar   +1 more source

Monocyte subsets and monocyte-related chemokines in Takayasu arteritis

Scientific Reports, 2022
AbstractThe pathogenesis of Takayasu arteritis (TAK) is poorly understood and no previous studies have analyzed monocytes in TAK. This study evaluated monocyte subsets and monocyte-related chemokines in the peripheral blood of TAK patients and healthy controls (HC). Monocyte subsets were identified as classical (CD14+CD16−), intermediate (CD14+CD16dim),
de Aguiar, Mariana Freitas, Torquato, Heron, Salu, Bruno Ramos, Oliveira, Ana Cecília Diniz, Oliva, Maria Luiza Vilela, Paredes-Gamero, Edgar Julian, Abdulahad, Wayel H., Brouwer, Elisabeth, de Souza, Alexandre W.S.   +8 more
openaire   +4 more sources

THE PHENOTYPE AND FUNCTION OF MONOCYTES IN PATIENTS WITH PULMONARY TUBERCULOSIS

Медицинская иммунология, 2014
. Peripheral blood monocytes were investigated in the patients with pulmonary tuberculosis. It was established that population of CD14+16+ monocytes was twofold increased in the patients with tuberculosis.
L. V. Sakhno, M. A. Tihonova, V. S. Kozhevnikov, V. V. Senjukov, N. V. Pronkina, S. D. Nikonov, O. A. Zhdanov, A. A. Ostanin, E. R. Chernykh   +8 more
doaj   +1 more source

Blood monocytes and their subsets: established features and open questions

Frontiers in Immunology, 2015
In contrast to the past reliance on morphology the identification and enumeration of blood monocytes is nowadays done with monoclonal antibodies and flow cytometry and this allows for subdivision into classical, intermediate and non-classical monocytes ...
Loems eZiegler-Heitbrock
doaj   +1 more source

Gene induction during differentiation of human monocytes into dendritic cells: an integrated study at the RNA and protein levels [PDF]

Funct Integr Genomics 1 (09/2001) 323-9, 2006
Changes in gene expression occurring during differentiation of human monocytes into dendritic cells were studied at the RNA and protein levels. These studies showed the induction of several gene classes corresponding to various biological functions. These functions encompass antigen processing and presentation, cytoskeleton, cell signalling and signal ...
arxiv   +1 more source

CCL2 recruits inflammatory monocytes to facilitate breast tumor metastasis

Nature, 2011
Macrophages, which are abundant in the tumour microenvironment, enhance malignancy. At metastatic sites, a distinct population of metastasis-associated macrophages promotes the extravasation, seeding and persistent growth of tumour cells.
Binzhi Qian, Jiu-feng Li, Hui Zhang, T. Kitamura, Jinghang Zhang, Liam R. Campion, Elizabeth A. Kaiser, L. Snyder, J. Pollard   +8 more
semanticscholar   +1 more source

Triggering of NOD2 Receptor Converts Inflammatory Ly6Chigh into Ly6Clow Monocytes with Patrolling Properties

Cell Reports, 2017
The signals that regulate the fate of circulating monocytes remain unknown. In the present study, we demonstrate that triggering of the NOD2 receptor by muramyl dipeptide (MDP) converts inflammatory Ly6Chigh monocytes into patrolling Ly6Clow monocytes ...
Anne-Julie Lessard, Manon LeBel, Benoit Egarnes, Paul Préfontaine, Peter Thériault, Arnaud Droit, Alexandre Brunet, Serge Rivest, Jean Gosselin   +8 more
doaj   +1 more source

High expression of antioxidant proteins in dendritic cells: possible implications in atherosclerosis [PDF]

Mol Cell Proteomics 5 (04/2006) 726-36, 2006
Dendritic cells (DCs) display the unique ability to activate naive T cells and to initiate primary T cell responses revealed in DC-T cell alloreactions. DCs frequently operate under stress conditions. Oxidative stress enhances the production of inflammatory cytokines by DCs.
arxiv   +1 more source