Results 121 to 130 of about 21,607,700 (130)

Monomeric C-reactive protein alters fibrin clot properties on endothelial cells

Thrombosis Research, 2012
Elevated plasma levels of C-reactive protein (CRP) are independently associated with increased risk of atherothrombosis. Several lines of evidence suggest that CRP has prothrombogenic effects on injured vessel wall(s) by enhancing tissue factor (TF) expression. Abnormal fibrin formation is correlated with increased thrombotic risk.
Rong, Li, Meiping, Ren, Mao, Luo, Ni, Chen, Zhuo, Zhang, Bo, Luo, Jianbo, Wu   +6 more
openaire   +2 more sources

FUNCTIONAL ACTIVITY OF MONOMERIC C-REACTIVE PROTEIN IN INTERVERTEBRAL DISC

Orthopaedic Proceedings
Monomeric C reactive protein (mCRP) presents important proinflammatory effects in endothelial cells, leukocytes, or chondrocytes. However, CRP in its pentameric form exhibits weak anti-inflammatory activity. It is used as a biomarker to follow severity and progression in infectious or inflammatory diseases, such as intervertebral disc degeneration ...
C. Ruiz-Fernández, D.A. Eldjoudi, M. Gonzalez-Rodríguez, A.C. Barreal, Y. Farrag, A. Mobasheri, J. Pino, D. Sakai, O. Gualillo   +8 more
openaire   +1 more source

Monomerization of C‐reactive protein requires glycoprotein IIb‐IIIa activation: pentraxins and platelet deposition

Journal of Thrombosis and Haemostasis, 2013
Pentraxins are inflammatory mediators linked to cardiovascular disease; however, their role in thrombosis remains to be fully elucidated.We investigated the role of pentraxins in thrombus formation on different vascular substrates under flow conditions.Native C-reactive protein (nCRP) and serum amyloid P (SAP) effects on thrombosis were evaluated under
De La Torre, R, Pena, E, Vilahur, G, Slevin, M, Badimon, L   +4 more
openaire   +3 more sources

Monomeric C reactive Protein Promotes Platelet Activation In Vitro and In Vivo

Heart, Lung and Circulation, 2009
J. Habersberger, S. Eisenhardt, N. Bassler, Y.C. Chen, J.D. Hohmann, I. Ahrens, K. Peter   +6 more
openaire   +1 more source

Dissociation of Pentameric to Monomeric C-Reactive Protein on Activated Platelets Localizes Inflammation to Atherosclerotic Plaques

Circulation Research, 2009
Andrew Murphy, Hagemeyer Ce, Karlheinz Peter   +2 more
exaly  

Dissociation of Pentameric to Monomeric C-Reactive Protein Localizes and Aggravates Inflammation

Circulation, 2014
Karlheinz Peter, Kevin Woollard
exaly  

A redox sensitivity-based method to quantify both pentameric and monomeric C-reactive protein in a single assay

Journal of Immunological Methods, 2019
Zhang Yanmin, Liu Shanhui, Lin Zhang
exaly  

Antibodies against monomeric C-reactive protein as a promising biomarker of lupus nephritis

Aswan University Medical Journal
Emad Farah Kholef, Janet S Toma, Abd ElRahman Abd ElHamed ElSayed, Mahmoud Gamal ElAgramy, Fatma Hussien Elnoby   +4 more
openaire   +1 more source

Pathogenic role of antibodies against monomeric C‐reactive protein in tubulointerstitial nephritis and uveitis syndrome

Internal Medicine Journal, 2014
exaly  

Pharmacological modulation of monomeric C-reactive protein to control chronic inflammatory disease

GCFN - 2024
openaire   +1 more source