Results 171 to 180 of about 23,062,194 (220)

Monomeric C-reactive protein--a key molecule driving development of Alzheimer's disease associated with brain ischaemia? [PDF]

Sci Rep, 2015
Slevin M, Matou S, Zeinolabediny Y, Corpas R, Weston R, Liu D, Boras E, Di Napoli M, Petcu E, Sarroca S, Popa-Wagner A, Love S, Font MA, Potempa LA, Al-Baradie R, Sanfeliu C, Revilla S, Badimon L, Krupinski J.   +18 more
europepmc   +1 more source

Photostability of Cyanine Dyes and Its Correlation to Their Photothermal and Photodynamic Effects

Chemistry – A European Journal, EarlyView.
Photostability (PS) of dyes is a crucial parameter for performance in biological applications, yet often underrated. Here PS of several cyanines is investigated. The method is carefully evaluated and designed as a general and easy tool to compare PS of NIR dyes.
Clara Schäfer, Bo W. Laursen
wiley   +1 more source

Encapsulation of Linear and Cyclic Alkanes in Water Within a Dimeric Deep‐Cavity Sulfonatocalix[4]arene Capsule

Chemistry – A European Journal, EarlyView.
Captured in water. A tetrasulfonated deep‐cavity calix[4]arene encapsulates linear and cyclic alkanes, as well as benzene and hexafluorobenzene, in water by forming a self‐assembled dimeric capsule. The binding affinity is guest size‐dependent. For linear alkanes, the affinity peaks at n‐hexane, while cyclooctane is the most strongly bound cycloalkane.
Nico Schneider, Sebastiano Casalino, Aldrik H. Velders, Rosa M. Gomila, Antonio Frontera, Stefan Kubik   +5 more
wiley   +1 more source

DNA Nanotechnology Meets Peptide and Protein Self‐Assembly

Chemistry – A European Journal, EarlyView.
Combining DNA nanotechnology with peptide and protein assembly provides complementary platforms for the rational engineering of functional biomaterials. This Perspective discusses the emerging field of self‐assembling DNA‐peptide and DNA‐protein hybrid systems that combine the structural precision and programmability of DNA nanotechnology with the ...
Marcel Hanke, Nanjundan Raghul, Adrian Keller, Veikko Linko, Verónica I. Dodero   +4 more
wiley   +1 more source

Complement factor H binding of monomeric C-reactive protein downregulates proinflammatory activity and is impaired with at risk polymorphic CFH variants. [PDF]

Sci Rep, 2016
Molins B, Fuentes-Prior P, Adán A, Antón R, Arostegui JI, Yagüe J, Dick AD.   +6 more
europepmc   +1 more source

Modular Assembly of a Biocatalytic Material for Stereoselective C─Si Bond Formation

Chemistry – A European Journal, EarlyView.
A modular, carrier‐free enzyme foam derived from Rhodothermus marinus cytochrome c combines structural stability with catalytic efficiency for stereoselective C─Si bond formation. Streptavidin (STV)‐mediated protein crosslinking creates a robust, self‐supporting materials platform for next‐generation biocatalysis.
Marc F. Münker, Annika J. Weber, Madleen Richter, Jennifer Kühne, Carmen M. Dominguez, Christof M. Niemeyer, Kersten S. Rabe   +6 more
wiley   +1 more source

Multimodal Imaging of Live Cells and Tumor Spheroids by a G‐Quadruplex DNA Selective Ru(II)Polypyridyl Probe

Chemistry – A European Journal, EarlyView.
Harnessing the light‑switch properties of Ru‑PDC3, we demonstrate that it binds to G‑quadruplex DNA within the nuclei of living cells where it can act as a probe for real‑time imaging or at higher concentrations/illumination it can act as photosensitizer inducing phototoxicity.
Karmel S. Gkika, Lorcan Holden, Giuseppe Avella, Rhianne C. Curley, Nirod K. Sarangi, Tia E. Keyes   +5 more
wiley   +1 more source

Long‐Acting Therapeutics in Pediatric Health: Bridging Innovation and Access

Clinical Pharmacology &Therapeutics, EarlyView.
Children have distinct therapeutic needs arising from age‐dependent physiology, disease epidemiology, formulation requirements, dosing considerations, and safety vulnerabilities. Despite substantial reductions in childhood mortality over the past three decades, nearly 5 million children under five died in 2023, with infectious diseases continuing to ...
Prajith Venkatasubramanian, Moherndran Archary, Daniel B. Hawcutt, Rachel Daley, Edmund Capparelli, Adeniyi Olagunju   +5 more
wiley   +1 more source

Next‐Generation Carbon‐Based Anodes for Alkali Metal‐Ion Batteries: Recent Progress on Biphenylene and Emerging Materials

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Recent advances in carbon‐based anodes for alkali metal‐ion batteries are critically reviewed, with emphasis on biphenylene and other emerging carbon allotropes. Biphenylene exhibits exceptional theoretical electrochemical properties beyond conventional graphite, highlighting its strong potential as a next‐generation anode material once scalable ...
Adewale Hammed Pasanaje, Nirpendra Singh
wiley   +1 more source

Influence of 6‐Trifluoromethyluracil Versus Chloride Counterions in the Properties of Bis‐(1,10‐Phenanthroline)chloridecopper(II) Motif: Spectroscopic and In Vitro Biological Activity Assays

European Journal of Inorganic Chemistry, EarlyView.
This work explores the influence of 6‐trifluoromethyluracil versus chloride counterions on the antibacterial and antitumoral activities of bis‐(1,10‐phenanthroline)chloridecopper(II) motif. The counterion modulates antibacterial potency and the identity of the dominant reactive species, while leaving DNA recognition by the shared cation essentially ...
Francisco Mastrobuono‐Cordeiro, Gabriele de M. Pereira, Douglas H. Nakahata, Stefano Scoditti, Fernanda V. P. de V. Azevedo, Letícia P. de Oliveira, Silmara C. L. Frajácomo, Javier Ellena, Pedro H. de O. Santiago, Daniel Reta, Gilberto C. Franchi, Wilton R. Lustri, Carmen S. P. Lima, Pedro P. Corbi, Raphael E. F. de Paiva   +14 more
wiley   +1 more source