Results 41 to 50 of about 152,845 (174)

C-reactive protein, immunothrombosis and venous thromboembolism

Frontiers in Immunology, 2022
C-reactive protein (CRP) is a member of the highly conserved pentraxin superfamily of proteins and is often used in clinical practice as a marker of infection and inflammation.
Caroline Dix, Caroline Dix, Johannes Zeller, Johannes Zeller, Hannah Stevens, Hannah Stevens, Hannah Stevens, Steffen U. Eisenhardt, Karen S. Cheung Tung Shing, Karen S. Cheung Tung Shing, Tracy L. Nero, Tracy L. Nero, Craig J. Morton, Craig J. Morton, Craig J. Morton, Michael W. Parker, Michael W. Parker, Michael W. Parker, Karlheinz Peter, Karlheinz Peter, Karlheinz Peter, James D. McFadyen, James D. McFadyen, James D. McFadyen, James D. McFadyen   +24 more
doaj   +1 more source

Monomeric C‐reactive protein induces the cellular pathology of Alzheimer's disease

Alzheimer’s & Dementia: Translational Research & Clinical Interventions, 2022
Introduction Human study shows that elevated C‐reactive protein (CRP) in blood impacts apolipoprotein E (APOE) ε4, but not APOE ε3 or APOE ε2, genotype to increase the risk of Alzheimer's disease (AD).
Qini Gan, Alfred Wong, Zhengrong Zhang, Hana Na, Hua Tian, Qiushan Tao, Ibraheem M. Rajab, Lawrence A. Potempa, Wei Qiao Qiu   +8 more
doaj   +1 more source

mCRP as a Biomarker of Adult-Onset Still’s Disease: Quantification of mCRP by ELISA

Frontiers in Immunology, 2022
BackgroundC-reactive protein (CRP) is a dynamic protein that undergoes conformational changes between circulating native pentameric CRP (pCRP), pentameric symmetrical forms (pCRP*) and monomeric (or modified) CRP (mCRP) forms.
Chitose Fujita, Chitose Fujita, Yasuo Sakurai, Yasuo Sakurai, Yuki Yasuda, Rino Homma, Cheng-Long Huang, Cheng-Long Huang, Masaaki Fujita, Masaaki Fujita, Masaaki Fujita, Masaaki Fujita   +11 more
doaj   +1 more source

The Cholesterol-Binding Sequence in Monomeric C-Reactive Protein Binds to the SARS-CoV-2 Spike Receptor-Binding Domain and Blocks Interaction With Angiotensin-Converting Enzyme 2

Frontiers in Immunology, 2022
The receptor-binding domain (RBD) of the spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) binds to the human angiotensin-converting enzyme 2 (ACE2) receptor, which is a prerequisite for the virus to enter the cell. C-reactive
Hai-yun Li, Hai-yun Li, Ning Gao, Cheng-yang Liu, Xiao-ling Liu, Feng Wu, Nini Dai, Jing Han, Jing Han, Qiu-yu Li   +9 more
doaj   +1 more source

Relevance of lipoproteins, membranes, and extracellular vesicles in understanding C-reactive protein biochemical structure and biological activities

Frontiers in Cardiovascular Medicine, 2022
Early purification protocols for C-reactive protein (CRP) often involved co-isolation of lipoproteins, primarily very low-density lipoproteins (VLDLs).
Lawrence A. Potempa, Wei Qiao Qiu, Wei Qiao Qiu, Wei Qiao Qiu, Ashley Stefanski, Ibraheem M. Rajab   +5 more
doaj   +1 more source

C-Reactive Protein and Cancer: Interpreting the Differential Bioactivities of Its Pentameric and Monomeric, Modified Isoforms

Frontiers in Immunology, 2021
C-reactive protein (CRP) was first recognized in the 1940s as a protein that appeared in blood during acute episodes of infectious disease. Its presence and pharmacodynamics were found in essentially all diseases that involved tissue damage and ...
Lawrence A. Potempa, Ibraheem M. Rajab, Margaret E. Olson, Peter C. Hart   +3 more
doaj   +1 more source

Curly protein nanofibril systems for improving thermal stability and copigmentation of hibiscus anthocyanins

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Anthocyanins are attractive natural colorants for clean‐label food applications; however, their widespread use is limited by poor thermal stability. Protein nanofibrils have recently emerged as promising natural stabilizers because of their high surface area and ability to interact with anthocyanins through non‐covalent interactions.
Vildan Eyiz, İsmail Tontul, Selman Türker   +2 more
wiley   +1 more source

Description of sediment core CRP-1

, 1998
Description of sediment core CRP-
CRP Science Team (6968168), CRP Science Team   +1 more
core   +1 more source

pCRP-mCRP Dissociation Mechanisms as Potential Targets for the Development of Small-Molecule Anti-Inflammatory Chemotherapeutics

Frontiers in Immunology, 2018
Circulating C-reactive protein (CRP) is a key acute-phase protein and one of the main clinical biomarkers for inflammation and infection. CRP is an important upstream mediator of inflammation and is associated with the onset of a number of important ...
Vittorio Caprio, Lina Badimon, Mario Di Napoli, Wen-Hui Fang, Glenn R. Ferris, Baoqiang Guo, Baoqiang Guo, Rocco S. Iemma, Donghui Liu, Donghui Liu, Yasmin Zeinolabediny, Yasmin Zeinolabediny, Mark Slevin, Mark Slevin, Mark Slevin, Mark Slevin   +15 more
doaj   +1 more source

Therapeutic Properties and Underlying Mechanisms of Traditional Chinese Medicine in Managing Rheumatoid Arthritis: An Integrative Review of Clinical and Molecular Findings

Phytotherapy Research, EarlyView.
The translational research framework integrating TCM for RA. The figure outlines a stepwise framework for the modernization and clinical translation of TCM in RA. Part 1 highlights the inheritance and development of TCM theory, including classical medical texts, traditional herbal knowledge, and syndrome differentiation–based treatment principles. Part
Jianting Wen, Jian Liu, Lei Wan, Fanfan Wang, Yang Li   +4 more
wiley   +1 more source