Results 21 to 30 of about 163,143 (174)
Frontiers in Immunology, 2021 Phagocytosis and the formation of reactive oxygen species (ROS) in phagocytic leukocytes are an effective killing mechanism of the innate host defense. These cellular processes of innate immunity function in a complex interplay with humoral factors.
Johannes Zeller +11 more
doaj +1 more source
Mood Disorder Begins in the Mouth: Periodontitis Mediates Anxiety-Like Behaviors. [PDF]
Adv Sci (Weinh)ABSTRACT The previous study elucidated that the C‐reactive protein (CRP)/bone morphogenetic protein 4 (BMP4) signaling pathway mediates periodontitis‐associated anxiety‐like behaviors in rats. This molecular crosstalk along the periodontal‐hippocampal axis provides novel insights into the etiology and mechanisms of emotional disorders. However, several
Chen Z, Li X.
europepmc +2 more sources
C-reactive protein: a target for therapy to reduce inflammation
Frontiers in Immunology, 2023 C-reactive protein (CRP) is well-recognized as a sensitive biomarker of inflammation. Association of elevations in plasma/serum CRP level with disease state has received considerable attention, even though CRP is not a specific indicator of a single ...
Salma A. Rizo-Téllez +5 more
doaj +1 more source
EMBO Molecular Medicine, 2022 C‐reactive protein (CRP) is an early‐stage acute phase protein and highly upregulated in response to inflammatory reactions. We recently identified a novel mechanism that leads to a conformational change from the native, functionally relatively inert ...
Johannes Zeller +22 more
doaj +1 more source
European review for medical and pharmacological sciences, 2023 Correction to: European Review for Medical and Pharmacological Sciences 2022; 26 (22): 8713-8718. DOI: 10.26355/eurrev_202212_30543- PMID: 36524490-published online on December 15, 2022. After publication, the authors applied a correction to the funding statement: The authors extend their appreciation to the deputyship for Research & Innovation ...
Al-Baradie, R.S. +12 more
openaire +2 more sources
In vitro generation and bioactivity evaluation of C-reactive protein intermediate. [PDF]
PLoS ONE, 2018 The conformational conversion of pentameric C-reactive protein (pCRP) to monomeric CRP (mCRP) has been shown to play important roles in the action of CRP in inflammation regulation.
Jian-Min Lv, Ming-Yu Wang
doaj +1 more source
C-Reactive Protein in Atherosclerosis—More than a Biomarker, but not Just a Culprit
Reviews in Cardiovascular Medicine, 2023 C-reactive protein (CRP) is a pentraxin that is mainly synthesized in the liver in response to inflammatory cytokines. It exists in two functionally and structurally distinct isoforms.
Kürsat Kirkgöz
doaj +1 more source
Extracellular vesicles are associated with C-reactive protein in sepsis
Scientific Reports, 2021 There is increasing evidence that C-reactive protein (CRP) can mediate inflammatory reactions following the transformation of functionally inert pentameric CRP (pCRP) into its structural isoform pCRP* and into monomeric CRP (mCRP).
Birgit Fendl +8 more
doaj +1 more source
C-reactive protein prolongs blood coagulation time in phospholipids-dependent coagulation tests
Научно-практическая ревматология, 2003 C-refctive protein prolongs blood coagulation time in phospholipids-dependent coagulation tests. O.P. Bliznukov, L.D. Kostin, A.J. Martinov, T.A. Lisitsina, T.M. Reshetnyak, V.J. Lauga Objective.
L D Kozmin +5 more
doaj +1 more source
Biochemically prepared C-reactive protein conformational states differentially affect C1q binding
BBA Advances, 2022 C-reactive protein (CRP) is commonly measured as an inflammatory marker in patient studies for coronary heart disease, autoimmune disease and recent acute infections.
Carrie L. Moon +4 more
doaj +1 more source