Results 21 to 30 of about 152,845 (174)

Mood Disorder Begins in the Mouth: Periodontitis Mediates Anxiety-Like Behaviors. [PDF]

Adv Sci (Weinh)
ABSTRACT The previous study elucidated that the C‐reactive protein (CRP)/bone morphogenetic protein 4 (BMP4) signaling pathway mediates periodontitis‐associated anxiety‐like behaviors in rats. This molecular crosstalk along the periodontal‐hippocampal axis provides novel insights into the etiology and mechanisms of emotional disorders. However, several
Chen Z, Li X.
europepmc   +2 more sources

C-reactive protein isoforms as prognostic markers of COVID-19 severity

Frontiers in Immunology, 2023
C-reactive protein (CRP), an active regulator of the innate immune system, has been related to COVID-19 severity. CRP is a dynamic protein undergoing conformational changes upon activation in inflammatory microenvironments between pentameric and ...
Blanca Molins, Marc Figueras-Roca, Marc Figueras-Roca, Oliver Valero, Víctor Llorenç, Víctor Llorenç, Sara Romero-Vázquez, Oriol Sibila, Alfredo Adán, Alfredo Adán, Carolina García-Vidal, Alex Soriano, Alex Soriano   +12 more
doaj   +1 more source

CRP Enhances the Innate Killing Mechanisms Phagocytosis and ROS Formation in a Conformation and Complement-Dependent Manner

Frontiers in Immunology, 2021
Phagocytosis and the formation of reactive oxygen species (ROS) in phagocytic leukocytes are an effective killing mechanism of the innate host defense. These cellular processes of innate immunity function in a complex interplay with humoral factors.
Johannes Zeller, Balázs Bogner, Jurij Kiefer, David Braig, David Braig, Oscar Winninger, Mark Fricke, Ebru Karasu, Karlheinz Peter, Karlheinz Peter, Markus Huber-Lang, Steffen Ulrich Eisenhardt   +11 more
doaj   +1 more source

C-reactive protein: a target for therapy to reduce inflammation

Frontiers in Immunology, 2023
C-reactive protein (CRP) is well-recognized as a sensitive biomarker of inflammation. Association of elevations in plasma/serum CRP level with disease state has received considerable attention, even though CRP is not a specific indicator of a single ...
Salma A. Rizo-Téllez, Salma A. Rizo-Téllez, Meriem Sekheri, Meriem Sekheri, János G. Filep, János G. Filep   +5 more
doaj   +1 more source

Association of monomeric C-Reactive Protein (m-CRP) with hypothalamic neurons after CRP hippo-campal administration in a model of dementia.

European review for medical and pharmacological sciences, 2022
The ensuing ischemia due to the disruption of blood supply to the brain is one of the most common causes of stroke. Evidence suggests a clear association of the ischemic injury with vascular dementia and Alzheimer's disease (AD). In response to the brain ischemia, a cascade reaction starts leading to neuronal damage due to oxidative stress and other ...
Al-Baradie, RS, Abdel-Hadi, AM, Ahmad, F, Alsagaby, SA, Slevin, M, Alturaiki, W, Madkhali, Y, Aljarallah, BM, Alqahtani, M, Miraj, M, Ahmad, I, Albaradie, N, Albaradie, R   +12 more
openaire   +3 more sources

monomeric/BrainSignalDistribution: v0.1

, 2021
First public release for reference in Delbrouck et ...
monomeric
core   +1 more source

Serum CRP interacts with SPARC and regulate immune response in severe cases of COVID-19 infection

Frontiers in Immunology, 2023
Serum C-reactive protein (CRP) has been found elevated during COVID-19 infection, and associated with systematic inflammation as well as a poor clinical outcome.
Chengyang Liu, Chenyang Zheng, Xipeng Shen, Ling Liang, Qiuyu Li   +4 more
doaj   +1 more source

A novel phosphocholine‐mimetic inhibits a pro‐inflammatory conformational change in C‐reactive protein

EMBO Molecular Medicine, 2022
C‐reactive protein (CRP) is an early‐stage acute phase protein and highly upregulated in response to inflammatory reactions. We recently identified a novel mechanism that leads to a conformational change from the native, functionally relatively inert ...
Johannes Zeller, Karen S Cheung Tung Shing, Tracy L Nero, James D McFadyen, Guy Krippner, Balázs Bogner, Sheena Kreuzaler, Jurij Kiefer, Verena K Horner, David Braig, Habiba Danish, Sara Baratchi, Mark Fricke, Xiaowei Wang, Michel G Kather, Bernd Kammerer, Kevin J Woollard, Prerna Sharma, Craig J Morton, Geoffrey Pietersz, Michael W Parker, Karlheinz Peter, Steffen U Eisenhardt   +22 more
doaj   +1 more source

Современные возможности определения и применения в клинике мономера С-реактивного белка [PDF]

, 2020
Aim. To develop a method for measuring circulating monomeric C-reactive protein and to determine the levels of C-reactive protein isoforms (native pentameric C-reactive protein and monomeric C-reactive protein) in patients with stable coronary artery ...
I. S. Melnikov, S. G. Kozlov, И. С. Мельников, М. Д. Зверева, О. С. Сабурова, O. S. Saburova, С. Г. Козлов, Z. A. Gabbasov, M. D. Zvereva, З. А. Габбасов   +9 more
core   +1 more source

Author Correction: Association of monomeric C-Reactive Protein (m-CRP) with hypothalamic neurons after CRP hippo-campal administration in a model of dementia.

European review for medical and pharmacological sciences, 2023
Correction to: European Review for Medical and Pharmacological Sciences 2022; 26 (22): 8713-8718. DOI: 10.26355/eurrev_202212_30543- PMID: 36524490-published online on December 15, 2022. After publication, the authors applied a correction to the funding statement: The authors extend their appreciation to the deputyship for Research & Innovation ...
Al-Baradie, R.S., Abdel-Hadi, A., Ahmad, F., Alsagaby, S.A., Slevin, M., Alturaiki, W., Madkhali, Y., Aljarallah, B.M., Alqahtani, M., Miraj, M., Ahmad, I., Albaradie, N., Albaradie, R.   +12 more
openaire   +2 more sources