Results 31 to 40 of about 152,845 (174)

In vitro generation and bioactivity evaluation of C-reactive protein intermediate. [PDF]

open access: yesPLoS ONE, 2018
The conformational conversion of pentameric C-reactive protein (pCRP) to monomeric CRP (mCRP) has been shown to play important roles in the action of CRP in inflammation regulation.
Jian-Min Lv, Ming-Yu Wang
doaj   +1 more source

C-Reactive Protein in Atherosclerosis—More than a Biomarker, but not Just a Culprit

open access: yesReviews in Cardiovascular Medicine, 2023
C-reactive protein (CRP) is a pentraxin that is mainly synthesized in the liver in response to inflammatory cytokines. It exists in two functionally and structurally distinct isoforms.
Kürsat Kirkgöz
doaj   +1 more source

Extracellular vesicles are associated with C-reactive protein in sepsis

open access: yesScientific Reports, 2021
There is increasing evidence that C-reactive protein (CRP) can mediate inflammatory reactions following the transformation of functionally inert pentameric CRP (pCRP) into its structural isoform pCRP* and into monomeric CRP (mCRP).
Birgit Fendl   +8 more
doaj   +1 more source

C-reactive protein prolongs blood coagulation time in phospholipids-dependent coagulation tests

open access: yesНаучно-практическая ревматология, 2003
C-refctive protein prolongs blood coagulation time in phospholipids-dependent coagulation tests. O.P. Bliznukov, L.D. Kostin, A.J. Martinov, T.A. Lisitsina, T.M. Reshetnyak, V.J. Lauga Objective.
L D Kozmin   +5 more
doaj   +1 more source

Biochemically prepared C-reactive protein conformational states differentially affect C1q binding

open access: yesBBA Advances, 2022
C-reactive protein (CRP) is commonly measured as an inflammatory marker in patient studies for coronary heart disease, autoimmune disease and recent acute infections.
Carrie L. Moon   +4 more
doaj   +1 more source

The High-Sensitivity C-Reactive Protein-Albumin-Lymphocyte Index Is a Prognostic Marker for All-Cause and Cardiovascular Mortality in Patients With ST-Elevation Myocardial Infarction. [PDF]

open access: yesCatheter Cardiovasc Interv
ABSTRACT Background Inflammation and immune dysfunction may worsen the prognosis of patients with ST‐segment elevation myocardial infarction (STEMI). Aims This study aimed to assess whether the high‐sensitivity C‐reactive protein–albumin–lymphocyte index (hsCALLYI) could be used to predict the prognosis of STEMI patients who received emergency ...
Ma X   +8 more
europepmc   +2 more sources

C-Reactive Protein: Pathophysiology, Diagnosis, False Test Results and a Novel Diagnostic Algorithm for Clinicians

open access: yesDiseases, 2023
The current literature provides a body of evidence on C-Reactive Protein (CRP) and its potential role in inflammation. However, most pieces of evidence are sparse and controversial.
Dimitra S. Mouliou
doaj   +1 more source

The Clinical Significance and Potential Role of C-Reactive Protein in Chronic Inflammatory and Neurodegenerative Diseases

open access: yesFrontiers in Immunology, 2018
C-reactive protein (CRP) is an acute-phase protein synthesized by hepatocytes in response to pro-inflammatory cytokines during inflammatory/infectious processes.
Ying-yi Luan   +2 more
doaj   +1 more source

Targeting C-Reactive Protein in Inflammatory Disease by Preventing Conformational Changes

open access: yesMediators of Inflammation, 2015
C-reactive protein (CRP) is a pentraxin that has long been employed as a marker of inflammation in clinical practice. Recent findings brought up the idea of CRP to be not only a systemic marker but also a mediator of inflammation.
J. R. Thiele   +5 more
doaj   +1 more source

C-reactive protein in major depressive disorder: Promise and challenge

open access: yesJournal of Affective Disorders Reports, 2022
Depressive disorders are characterized by persistent low mood, loss of interest and pleasure, decreased energy, varying levels of social and occupational dysfunction.
Angelos Halaris   +3 more
doaj   +1 more source

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