Results 31 to 40 of about 163,143 (174)

Современные возможности определения и применения в клинике мономера С-реактивного белка [PDF]

, 2020
Aim. To develop a method for measuring circulating monomeric C-reactive protein and to determine the levels of C-reactive protein isoforms (native pentameric C-reactive protein and monomeric C-reactive protein) in patients with stable coronary artery ...
I. S. Melnikov, S. G. Kozlov, И. С. Мельников, М. Д. Зверева, О. С. Сабурова, O. S. Saburova, С. Г. Козлов, Z. A. Gabbasov, M. D. Zvereva, З. А. Габбасов   +9 more
core   +1 more source

C-Reactive Protein: Pathophysiology, Diagnosis, False Test Results and a Novel Diagnostic Algorithm for Clinicians

Diseases, 2023
The current literature provides a body of evidence on C-Reactive Protein (CRP) and its potential role in inflammation. However, most pieces of evidence are sparse and controversial.
Dimitra S. Mouliou
doaj   +1 more source

Targeting C-Reactive Protein in Inflammatory Disease by Preventing Conformational Changes

Mediators of Inflammation, 2015
C-reactive protein (CRP) is a pentraxin that has long been employed as a marker of inflammation in clinical practice. Recent findings brought up the idea of CRP to be not only a systemic marker but also a mediator of inflammation.
J. R. Thiele, J. Zeller, H. Bannasch, G. B. Stark, K. Peter, S. U. Eisenhardt   +5 more
doaj   +1 more source

The Clinical Significance and Potential Role of C-Reactive Protein in Chronic Inflammatory and Neurodegenerative Diseases

Frontiers in Immunology, 2018
C-reactive protein (CRP) is an acute-phase protein synthesized by hepatocytes in response to pro-inflammatory cytokines during inflammatory/infectious processes.
Ying-yi Luan, Yong-ming Yao, Yong-ming Yao   +2 more
doaj   +1 more source

C-reactive protein in major depressive disorder: Promise and challenge

Journal of Affective Disorders Reports, 2022
Depressive disorders are characterized by persistent low mood, loss of interest and pleasure, decreased energy, varying levels of social and occupational dysfunction.
Angelos Halaris, Danika Prochaska, Ashley Stefanski, Maria Filip   +3 more
doaj   +1 more source

C-reactive protein, immunothrombosis and venous thromboembolism

Frontiers in Immunology, 2022
C-reactive protein (CRP) is a member of the highly conserved pentraxin superfamily of proteins and is often used in clinical practice as a marker of infection and inflammation.
Caroline Dix, Caroline Dix, Johannes Zeller, Johannes Zeller, Hannah Stevens, Hannah Stevens, Hannah Stevens, Steffen U. Eisenhardt, Karen S. Cheung Tung Shing, Karen S. Cheung Tung Shing, Tracy L. Nero, Tracy L. Nero, Craig J. Morton, Craig J. Morton, Craig J. Morton, Michael W. Parker, Michael W. Parker, Michael W. Parker, Karlheinz Peter, Karlheinz Peter, Karlheinz Peter, James D. McFadyen, James D. McFadyen, James D. McFadyen, James D. McFadyen   +24 more
doaj   +1 more source

Monomeric C‐reactive protein induces the cellular pathology of Alzheimer's disease

Alzheimer’s & Dementia: Translational Research & Clinical Interventions, 2022
Introduction Human study shows that elevated C‐reactive protein (CRP) in blood impacts apolipoprotein E (APOE) ε4, but not APOE ε3 or APOE ε2, genotype to increase the risk of Alzheimer's disease (AD).
Qini Gan, Alfred Wong, Zhengrong Zhang, Hana Na, Hua Tian, Qiushan Tao, Ibraheem M. Rajab, Lawrence A. Potempa, Wei Qiao Qiu   +8 more
doaj   +1 more source

mCRP as a Biomarker of Adult-Onset Still’s Disease: Quantification of mCRP by ELISA

Frontiers in Immunology, 2022
BackgroundC-reactive protein (CRP) is a dynamic protein that undergoes conformational changes between circulating native pentameric CRP (pCRP), pentameric symmetrical forms (pCRP*) and monomeric (or modified) CRP (mCRP) forms.
Chitose Fujita, Chitose Fujita, Yasuo Sakurai, Yasuo Sakurai, Yuki Yasuda, Rino Homma, Cheng-Long Huang, Cheng-Long Huang, Masaaki Fujita, Masaaki Fujita, Masaaki Fujita, Masaaki Fujita   +11 more
doaj   +1 more source

Western blot of dialyzed CRP and treated CRP with urea and EDTA.

, 2019
The dialyzed CRP appeared at much higher sizes than the treated CRP did, suggesting pentameric CRP (pCRP) and monomeric CRP (mCRP), respectively. Western blotting showed that the mCRP was detected with the anti-CRP antibody (ab32412).
So Ra Kim (458940), Jung-A. Song (6672554), Eun Na Kim (3234693), Chong Jai Kim (212418), Ki-Bong Kim (4252093), Han Choe (202796), Se Jin Oh (3171000), Jae-Sung Choi (238255)   +7 more
core   +1 more source

The Cholesterol-Binding Sequence in Monomeric C-Reactive Protein Binds to the SARS-CoV-2 Spike Receptor-Binding Domain and Blocks Interaction With Angiotensin-Converting Enzyme 2

Frontiers in Immunology, 2022
The receptor-binding domain (RBD) of the spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) binds to the human angiotensin-converting enzyme 2 (ACE2) receptor, which is a prerequisite for the virus to enter the cell. C-reactive
Hai-yun Li, Hai-yun Li, Ning Gao, Cheng-yang Liu, Xiao-ling Liu, Feng Wu, Nini Dai, Jing Han, Jing Han, Qiu-yu Li   +9 more
doaj   +1 more source