Results 81 to 90 of about 272,971 (193)

Biochemical properties of Paracoccus denitrificans FnrP:Reactions with molecular oxygen and nitric oxide [PDF]

, 2016
In Paracoccus denitrificans, three CRP/FNR family regulatory proteins, NarR, NnrR and FnrP, control the switch between aerobic and anaerobic (denitrification) respiration.
A Volbeda, A Yan, AJ Jervis, Andrew J. Thomson, AS Fleischhacker, B Weiss, B Zhang, CP Tseng, CT Przysiecki, CV Popescu, D Ralt, DJ Richardson, DJ Shaw, DM Bates, F Sievers, G Sawers, H Beinert, H Reents, J Crack, J Edwards, J Green, Jason C. Crack, JC Crack, JC Crack, JC Crack, JC Crack, JC Crack, JC Crack, JC Crack, JC Crack, JC Crack, JC Drapier, L Bergaust, LJ Moore, LR Bakken, M Matsui, Matthew I. Hutchings, MC Broillet, MF Otten, MI Hutchings, MI Hutchings, MM Bradford, N Filenko, Nick E. Le Brun, NJ Watmough, P Bouchal, PJ Kiley, R Bruckdorfer, R Veldman, RJ Spanning Van, RJ Spanning van, SA Ibrahim, SB Melville, ST Pullan, VR Sutton, WG Zumft, YM Kwon, YY Lee   +57 more
core   +1 more source

C-Reactive Protein and Cancer—Diagnostic and Therapeutic Insights

Frontiers in Immunology, 2020
Cancer disease describes any pathology involving uncontrolled cell growth. As cells duplicate, they can remain localized in defined tissues, forming tumor masses and altering their microenvironmental niche, or they can disseminate throughout the body in ...
Peter C. Hart, Ibraheem M. Rajab, May Alebraheem, Lawrence A. Potempa   +3 more
doaj   +1 more source

Peptidylarginine deiminase and deiminated proteins are detected throughout early halibut ontogeny - Complement components C3 and C4 are post-translationally deiminated in halibut (Hippoglossus hippoglossus L.) [PDF]

, 2019
Post-translational protein deimination is mediated by peptidylarginine deiminases (PADs), which are calcium dependent enzymes conserved throughout phylogeny with physiological and pathophysiological roles. Protein deimination occurs via the conversion of
Bowden, T., Bowden, T., Bragason, B.T., Bragason, B.T., Bricknell, I.R., Bricknell, I.R., Dodds, A.W., Dodds, A.W., Gudmundsdottir, S., Gudmundsdottir, S., Hristova, M., Hristova, M., Lange, S., Lange, S., Magnadóttir, B., Magnadóttir, B., Nicholas, A.P., Nicholas, A.P.   +17 more
core   +3 more sources

Hydrogen‐Enriched Hyaluronic Acid Dressing Ameliorates Diabetic Foot Ulcer via Promoting Mitophagy

Journal of Diabetes, Volume 18, Issue 4, April 2026.
The combination of VSD and hydrogen‐rich saline is used to treat diabetic foot ulcers. In vitro and in vivo studies reveal that hydrogen‐enrich hyaluronic acid dressings enhance skin fibroblast repair ability by regulating mitophagy via the SIRT3 and its downstream signaling pathways, ultimately accelerating wound healing in diabetic foot ulcers ...
Ziyu Xu, Xinyu Cui, Houbin Chu, Hao Wan, Yunbo Xie, Ying Wang, Qingbin Ni, Xiaolin Ding, Guohua Song   +8 more
wiley   +1 more source

Functionality of C-Reactive Protein for Atheroprotection

Frontiers in Immunology, 2019
C-reactive protein (CRP) is a pentameric molecule made up of identical monomers. CRP can be seen in three different forms: native pentameric CRP (native CRP), non-native pentameric CRP (non-native CRP), and monomeric CRP (mCRP).
Sanjay K. Singh, Alok Agrawal
doaj   +1 more source

Anti-Monomeric C-Reactive Protein Antibody Ameliorates Arthritis and Nephritis in Mice

Journal of Immunology, 2021
Conformation-specific Ags are ideal targets for mAb-based immunotherapy. Here, we demonstrate that the monomeric form of C-reactive protein (mCRP) is a specific therapeutic target for arthritis and nephritis in a murine model.
Chitose K. Fujita, Yasuo Sakurai, Y. Yasuda, Y. Takada, Cheng‐long Huang, M. Fujita   +5 more
semanticscholar   +1 more source

Bioactive Phytochemical Compounds in Medicago sativa L. (Alfalfa): A Systematic Review of Biological Properties and Therapeutic Relevance in Nutraceutical and Functional Food Implications

Food Frontiers, Volume 7, Issue 2, March 2026.
ABSTRACT Medicago sativa L. (alfalfa) harbors a remarkably diverse reservoir of bioactive secondary metabolites. Flavonoids, isoflavones, and triterpenoid saponins dominate its bioactivity landscape, driving potent antioxidant, anti‐inflammatory, antimicrobial, estrogenic, hypolipidemic, and cytotoxic actions through redox modulation, membrane ...
Parham Joolaei Ahranjani, Hamid Rashidi Nodeh, Zahra Esfandiari, Giovanna Ferrentino   +3 more
wiley   +1 more source

The Multiple Faces of C-Reactive Protein—Physiological and Pathophysiological Implications in Cardiovascular Disease

Molecules, 2019
C-reactive protein (CRP) is an intriguing protein which plays a variety of roles in either physiological or pathophysiological states. For years it has been regarded merely as a useful biomarker of infection, tissue injury and inflammation, and it was ...
Magdalena Boncler, Yi Wu, Cezary Watala
doaj   +1 more source

ApoFnr binds as a monomer to promoters regulating expression of enterotoxin genes of Bacillus cereus. [PDF]

, 2008
International audienceBacillus cereus Fnr is a member of the Crp/Fnr (cAMP-binding protein/fumarate nitrate reduction regulatory protein) family of helix-turn-helix transcriptional regulators. It is essential for the expression of Hbl and Nhe enterotoxin
Armengaud, J., Duport, Catherine, Esbelin, Julia, Jouanneau, Yves   +3 more
core  

Neuroinflammation in Preclinical Alzheimer's Disease: A Review of Current Evidence [PDF]

, 2018
The pathology of sporadic Alzheimer’s disease (AD) may be present at mid-life and precede the prodromal and clinical dementia syndromes associated with the disorder by decades.
Raymont, Vanessa, Ritchie, Karen, Watermeyer, Tamlyn   +2 more
core   +2 more sources