Autophagy in Saccharomyces cerevisiae requires the monomeric GTP-binding proteins, Arl1 and Ypt6. [PDF]
Autophagy, 2016 Macroautophagy/autophagy is a cellular degradation process that sequesters organelles or proteins into a double-membrane structure called the phagophore; this transient compartment matures into an autophagosome, which then fuses with the lysosome or vacuole to allow hydrolysis of the cargo.
Yang S, Rosenwald AG.
europepmc +6 more sources
The roles of monomeric GTP-binding proteins in macroautophagy in Saccharomyces cerevisiae. [PDF]
Int J Mol Sci, 2014 Autophagy is a cellular degradation process that sequesters components into a double-membrane structure called the autophagosome, which then fuses with the lysosome or vacuole for hydrolysis and recycling of building blocks. Bulk phase autophagy, also known as macroautophagy, controlled by specific Atg proteins, can be triggered by a variety of ...
Yang S, Rosenwald AG.
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Ethylene Regulates Monomeric GTP-Binding Protein Gene Expression and Activity in Arabidopsis [PDF]
Plant Physiology, 2003 AbstractEthylene rapidly and transiently up-regulates the activity of several monomeric GTP-binding proteins (monomeric G proteins) in leaves of Arabidopsis as determined by two-dimensional gel electrophoresis and autoradiographic analyses. The activation is suppressed by the receptor-directed inhibitor 1-methylcyclopropene.
И. Е. Мошков +4 more
semanticscholar +4 more sources
Ethylene Rapidly Up-Regulates the Activities of Both Monomeric GTP-Binding Proteins and Protein Kinase(s) in Epicotyls of Pea [PDF]
Plant Physiology, 2003 Abstract It is demonstrated that, in etiolated pea (Pisum sativum) epicotyls, ethylene affects the activation of both monomeric GTP-binding proteins (monomeric G-proteins) and protein kinases. For monomeric G-proteins, the effect may be a rapid (2 min) and bimodal up-regulation, a transiently unimodal activation, or a transient down ...
И. Е. Мошков +4 more
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Study of the Interaction of the Myelin Monomeric GTP‐Binding Proteins with Other Brain Proteins [PDF]
Journal of Neurochemistry, 1997 Abstract: Although several monomeric GTP‐binding proteins have been found in myelin, the signaling pathways in which they operate are not known. To define these signaling pathways we searched for specific target proteins that interact with the myelin monomeric GTP‐binding proteins. A blot overlay approach was used.
Alicia Rodriguez‐Gabin +3 more
semanticscholar +4 more sources
Characterization of the Interaction of the Monomeric GTP‐Binding Protein Rab3a with Geranylgeranyl Transferase II [PDF]
European Journal of Biochemistry, 1996 The monomeric GTP‐binding protein Rab3a controls exocytosis in neuroendocrine and neuronal cells. Like other members of the Rab family, Rab3a is posttranslationally modified by the addition of hydrophobic geranylgeranyl groups to its C‐terminus. The geranylgeranylation reaction is catalysed by the heterotrimeric geranylgeranyl transferase II.
Ludger Johannes +4 more
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The RhoGDIβ-Rac1-CARD9 Signaling Module Mediates Islet β-Cell Dysfunction Under Chronic Hyperglycemia. [PDF]
CellsSmall (monomeric) GTP-binding proteins (smgs; Cdc42 and Rac1) play requisite roles in islet beta cell function, including glucose-stimulated insulin secretion. In addition, emerging evidence suggests that sustained (constitutive) activation of smgs (e.g.,
Kowluru A, Wang JM.
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Neurology International, 2023 Recent discoveries suggest links between abnormalities in cell morphogenesis in the brain and the functional deficiency of molecules controlling signal transduction in glial cells such as oligodendroglia.
Shoya Fukatsu +8 more
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A specific role for importin-5 and NASP in the import and nuclear hand-off of monomeric H3
eLife, 2022 Core histones package chromosomal DNA and regulate genomic transactions, with their nuclear import and deposition involving importin-β proteins and a dedicated repertoire of histone chaperones. Previously, a histone H3-H4 dimer has been isolated bound to
Alonso Javier Pardal +1 more
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Structure of UreG/UreF/UreH complex reveals how urease accessory proteins facilitate maturation of Helicobacter pylori urease. [PDF]
PLoS Biology, 2013 Urease is a metalloenzyme essential for the survival of Helicobacter pylori in acidic gastric environment. Maturation of urease involves carbamylation of Lys219 and insertion of two nickel ions at its active site. This process requires GTP hydrolysis and
Yu Hang Fong +5 more
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