Staging concept for aging management: Definition, mechanism, and coping strategies
We divided the overall aging stage into “pre‐aging”, “aging compensation”, and “aging disability”. For each stage, we delineate the clinical presentations, biological phenomena, theoretical underpinnings, and key management priorities. Abstract Aging, as a gradual and largely irreversible biological process, characterized by declining organismal ...
Zhonghan Wang +6 more
wiley +1 more source
Cytokine production of mononuclear leukocytes in response to respiratory syncytial virus is increased in COPD but suppressed in non-COPD tobacco smokers. [PDF]
Yanik SD +10 more
europepmc +1 more source
HSP70 in human polymorphonuclear and mononuclear leukocytes: comparison of the protein content and transcriptional activity of HSPA genes. [PDF]
Boyko AA +4 more
europepmc +1 more source
Peptide‐directed nanovehicles enabling tumor‐selective ROS amplification and antitumor immunity
Cancer cells are vulnerable to oxidative stress, yet exploit immune tolerance to escape destruction. In contrast, their metabolic profile is markedly altered to support rapid proliferation, accompanied by elevated production of reactive oxygen species (ROS).
Manuela Calin +3 more
wiley +1 more source
Adipokine secretion from adipose tissue may be involved in obesity‐related asthma, but it is unknown how adipokine levels relate to asthma characteristics. Plasma adipokines were measured in well‐characterized lean, overweight or obese patients with mild‐to‐moderate or severe asthma.
Lars I. Andersson +20 more
wiley +1 more source
Shedding light on the effects of blood on meniscus tissue: the role of mononuclear leukocytes in mediating meniscus catabolism. [PDF]
Betsch K +5 more
europepmc +1 more source
Hydrogen sulfide exposure induces NLRP3 inflammasome-dependent IL-1β and IL-18 secretion in human mononuclear leukocytes in vitro. [PDF]
Basic A +3 more
europepmc +1 more source
Western analysis of intracellular interleukin-8 in human mononuclear leukocytes. [PDF]
Miskolci V +3 more
europepmc +1 more source

