Results 21 to 30 of about 55,865 (148)

Isoprene Oxidation by the Gram-Negative Model bacterium Variovorax sp. WS11

Microorganisms, 2020
Plant-produced isoprene (2-methyl-1,3-butadiene) represents a significant portion of global volatile organic compound production, equaled only by methane.
Robin A. Dawson, Nasmille L. Larke-Mejía, Andrew T. Crombie, Muhammad Farhan Ul Haque, J. Colin Murrell   +4 more
doaj   +1 more source

SAR202 Genomes from the Dark Ocean Predict Pathways for the Oxidation of Recalcitrant Dissolved Organic Matter

mBio, 2017
Deep-ocean regions beyond the reach of sunlight contain an estimated 615 Pg of dissolved organic matter (DOM), much of which persists for thousands of years.
Zachary Landry, Brandon K. Swan, Gerhard J. Herndl, Ramunas Stepanauskas, Stephen J. Giovannoni   +4 more
doaj   +1 more source

Pyridine Nucleotide Coenzyme Specificity of p-Hydroxybenzoate Hydroxylase and Related Flavoprotein Monooxygenases

Frontiers in Microbiology, 2018
p-Hydroxybenzoate hydroxylase (PHBH; EC 1.14.13.2) is a microbial group A flavoprotein monooxygenase that catalyzes the ortho-hydroxylation of 4-hydroxybenzoate to 3,4-dihydroxybenzoate with the stoichiometric consumption of NAD(P)H and oxygen.
Adrie H. Westphal, Dirk Tischler, Florian Heinke, Sarah Hofmann, Janosch A. D. Gröning, Dirk Labudde, Willem J. H. van Berkel   +6 more
doaj   +1 more source

Characterisation of ascocorynin biosynthesis in the purple jellydisc fungus Ascocoryne sarcoides

Fungal Biology and Biotechnology, 2022
Background Non-ribosomal peptide synthetase-like (NRPS-like) enzymes are highly enriched in fungal genomes and can be discriminated into reducing and non-reducing enzymes.
Carsten Wieder, Roberta Peres da Silva, Jessica Witts, Christof Martin Jäger, Elena Geib, Matthias Brock   +5 more
doaj   +1 more source

Flavin Conjugated Polydopamine Nanoparticles Displaying Light-Driven Monooxygenase Activity

Frontiers in Chemistry, 2019
A hybrid of flavin and polydopamine (PDA) has been explored as a photocatalyst, drawing inspiration from natural flavoenzymes. Light-driven monoxygenase activity has been demonstrated through the oxidation of indole under blue light irradiation in ...
Leander Crocker, Ljiljana Fruk
doaj   +1 more source

3-Hydroxybenzoate 6-Hydroxylase from Rhodococcus jostii RHA1 Contains a Phosphatidylinositol Cofactor

Frontiers in Microbiology, 2017
3-Hydroxybenzoate 6-hydroxylase (3HB6H, EC 1.13.14.26) is a FAD-dependent monooxygenase involved in the catabolism of aromatic compounds in soil microorganisms. 3HB6H is unique among flavoprotein hydroxylases in that it harbors a phospholipid ligand. The
Stefania Montersino, Evelien te Poele, Roberto Orru, Adrie H. Westphal, Arjan Barendregt, Albert J. R. Heck, Robert van der Geize, Lubbert Dijkhuizen, Andrea Mattevi, Willem J. H. van Berkel   +9 more
doaj   +1 more source

Advances in 4-Hydroxyphenylacetate-3-hydroxylase Monooxygenase

Molecules, 2023
Catechols have important applications in the pharmaceutical, food, cosmetic, and functional material industries. 4-hydroxyphenylacetate-3-hydroxylase (4HPA3H), a two-component enzyme system comprising HpaB (monooxygenase) and HpaC (FAD oxidoreductase ...
Kai Yang, Qianchao Zhang, Weirui Zhao, Sheng Hu, Changjiang Lv, Jun Huang, Jiaqi Mei, Lehe Mei   +7 more
doaj   +1 more source

P-LinK: A method for generating multicomponent cytochrome P450 fusions with variable linker length

BioTechniques, 2014
Fusion protein construction is a widely employed biochemical technique, especially when it comes to multi-component enzymes such as cytochrome P450s. Here we describe a novel method for generating fusion proteins with variable linker lengths, protein ...
Ketaki D. Belsare, Anna Joëlle Ruff, Ronny Martinez, Amol V. Shivange, Hemanshu Mundhada, Dirk Holtmann, Jens Schrader, Ulrich Schwaneberg   +7 more
doaj   +1 more source

Mechanism of Rifampicin Inactivation in Nocardia farcinica. [PDF]

PLoS ONE, 2016
A novel mechanism of rifampicin (Rif) resistance has recently been reported in Nocardia farcinica. This new mechanism involves the activity of rifampicin monooxygenase (RifMO), a flavin-dependent monooxygenase that catalyzes the hydroxylation of Rif ...
Heba Abdelwahab, Julia S Martin Del Campo, Yumin Dai, Camelia Adly, Sohby El-Sohaimy, Pablo Sobrado   +5 more
doaj   +1 more source

Optimisation of hypocrellin production in Shiraia-like fungi via genetic modification involving a transcription factor gene and a putative monooxygenase gene

Mycology
Shiraia-like fungi, which are rare parasitic fungi found around bamboo, play an important role in traditional medicine. Their main active component, hypocrellin, is widely used in medicine, food, and cosmetics.
Zi-Min Lu, Run-Tong Zhang, Xiao-Bo Huang, Xue-Ting Cao, Xiao-Ye Shen, Li Fan, Cheng-Lin Hou   +6 more
doaj   +1 more source