Results 1 to 10 of about 71,504 (306)
Flavin dependent monooxygenases
Archives of Biochemistry and Biophysics, 2014 Flavin-dependent monooxygenases catalyze a wide variety of chemo-, regio- and enantioselective oxygenation reactions. As such, they are involved in key biological processes ranging from catabolism, detoxification and biosynthesis, to light emission and axon guidance.
Dirk Tischler +2 more
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New frontiers in flavin-dependent monooxygenases
Archives of Biochemistry and Biophysics, 2021 Flavin-dependent monooxygenases catalyze a wide variety of redox reactions in important biological processes and are responsible for the synthesis of highly complex natural products.
Pablo Sobrado, Renata A G Reis, Hao Li
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ChemBioChem, 2022 AbstractMethods for facile site‐selective modifications of proteins are in high demand. We have recently shown that a flavin transferase can be used for site‐specific covalent attachment of a chromo‐ and fluorogenic flavin (FMN) to any targeted protein. Although this Flavin‐tag method resulted in efficient labeling of proteins in vitro, labelling in E.
Marco Fraaije
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Annual Review of Biochemistry, 2018 Flavin dependent halogenases (FDHs) catalyze the halogenation of organic substrates by coordinating reactions of reduced flavin, molecular oxygen, and chloride.
Jared Lewis, Mary Andorfer
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Flavin-dependent biocatalysts in synthesis
Tetrahedron, 2019 The diverse chemistry possible with flavin cofactors positions flavin-dependent enzymes as versatile synthetic tools. This focused review highlights applications of flavin-dependent enzymes in organic synthesis. Select examples of monoamine oxidases, ene-
Alison Narayan
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ACS Catalysis, 2019 Flavin-dependent halogenases are known to regioselectively introduce halide substituents into aromatic moieties, for example, the indole ring of tryptophan.
Tilman Kottke +2 more
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The World of Algae Reveals a Broad Variety of Cryptochrome Properties and Functions
Frontiers in Plant Science, 2021 Algae are photosynthetic eukaryotic (micro-)organisms, lacking roots, leaves, and other organs that are typical for land plants. They live in freshwater, marine, or terrestrial habitats.
Jan Petersen +6 more
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Journal of the American Chemical Society, 2023 Most flavin-dependent enzymes contain a dissociable flavin cofactor. We present a new approach for installing a covalent bond between a flavin cofactor and its hosting protein. By using a flavin transferase and carving a flavinylation motif in target proteins, we demonstrate that ‘dissociable’ flavoproteins can be turned into covalent flavoproteins ...
Yapei Tong +5 more
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Enhanced small green fluorescent proteins as a multisensing platform for biosensor development
Frontiers in Bioengineering and Biotechnology, 2022 Engineered light, oxygen, and voltage (LOV)-based proteins are able to fluoresce without oxygen requirement due to the autocatalytic incorporation of exogenous flavin as a chromophore thus allowing for live cell imaging under hypoxic and anaerobic ...
Guo-Teng Liang +25 more
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Understanding flavin electronic structure and spectra
WIREs Computational Molecular Science, 2021 Flavins have emerged as central to electron bifurcation, signaling, and countless enzymatic reactions. In bifurcation, two electrons acquired as a pair are separated in coupled transfers wherein the energy of both is concentrated on one of the two.
R. Kar +2 more
semanticscholar +1 more source