Results 171 to 180 of about 93,045 (249)

Effect of cis- and trans-Monounsaturated Fatty Acids on Palmitate Toxicity and on Palmitate-induced Accumulation of Ceramides and Diglycerides. [PDF]

open access: yesInt J Mol Sci, 2020
Sarnyai F   +9 more
europepmc   +1 more source

Targeting C12ORF49‐Mediated Ferroptosis in Hepatocellular Carcinoma

open access: yesJGH Open, Volume 10, Issue 2, February 2026.
ABSTRACT Hepatocellular carcinoma (HCC) remains a leading cause of cancer‐related mortality worldwide, underscoring the urgent need for novel therapeutic strategies. Recent studies have highlighted the pivotal role of ferroptosis, an iron‐dependent form of regulated cell death driven by lipid peroxidation, in cancer biology.
Yuexin Liu   +4 more
wiley   +1 more source

Metabolomic Analysis of Phytophthora parasitica Growth in the Presence of β‐sitosterol Indicates Adaptive Mechanisms Modulated by Sterols

open access: yesJournal of Basic Microbiology, Volume 66, Issue 2, February 2026.
ABSTRACT Phytophthora parasitica is a generalist phytopathogenic oomycete that infects a series of crops with great economic interest, including tomato, tobacco, and citrus species. Sterols are essential lipids in eukaryotic organisms, playing a fundamental role in the structure and function of the cell membrane.
Pâmela Ponce Martins   +7 more
wiley   +1 more source

State‐of‐the‐Art Strategies for Circular RNA in Cancers: Opportunity and Challenge

open access: yesMedComm, Volume 7, Issue 2, February 2026.
Overview of circular RNA in tumors. ABSTRACT Circular RNAs (circRNAs) are characterized by their covalently closed structure, remarkable stability, and precise spatiotemporal regulation, evolving from once‐overlooked transcriptional byproducts to pivotal molecular regulators.
Zehao Ding   +6 more
wiley   +1 more source

Sex‐Specific Subcutaneous Adipose Tissue Transcriptome in Obesity: Insights From Monozygotic Twin Pairs Discordant for BMI

open access: yesObesity, Volume 34, Issue 2, Page 394-406, February 2026.
ABSTRACT Objective We investigated the impact of sex on the subcutaneous adipose tissue (AT) transcriptome and its obesity‐related adaptations. Methods We studied rare BMI‐discordant monozygotic twin pairs (ΔBMI > 2.5 kg/m2; 21 female, 16 male pairs) to assess how sex affects AT and whole‐body metabolism.
Hanna Haltia   +12 more
wiley   +1 more source

Key Determinants of Weight Loss Trajectory Across Different Periods of a Behavioral Weight Loss Intervention

open access: yesObesity, Volume 34, Issue 2, Page 357-371, February 2026.
ABSTRACT Objective This longitudinal study aims to identify the key factors influencing the weight loss trajectory during a 24‐week intervention and their relevance at different stages of the treatment. Methods We studied 1252 participants (age 18–65 years) of a cognitive behavioral program to lose weight.
Rocío De la Peña‐Armada   +4 more
wiley   +1 more source

Synechococcus Under Stress: Contrasting Physiological and Transcriptional Responses to Salinity and Temperature in Marine Versus Euryhaline Strains

open access: yesEnvironmental Microbiology Reports, Volume 18, Issue 1, February 2026.
Two model strains of Synechococcus sp.—the marine RS9907 and the euryhaline WH5701—exhibit distinct physiological responses to salinity after long acclimations at optimal and cold growth temperatures. Transcriptomic and photochemical analyses reveal drastic differences in their regulatory strategies and photosynthetic activity across a salinity ...
Isabel Escribano‐Gómez   +6 more
wiley   +1 more source

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