Results 71 to 80 of about 617,785 (192)
Background Nitric oxide (NO) imbalance appears to be important in the pathogenesis of allergic rhinitis. NO is synthesized from L-arginine by NO synthase (NOS).
Husamettin Yasar +9 more
core +1 more source
Introductıon Ureteral obstruction is a common pathology and caused kidney fibrosis and dysfunction at late period. In this present, we investigated the antifibrotic and antiinflammatory effects of montelukast which is cysteinyl leukotriene receptor ...
Alper Otunctemur +8 more
doaj +1 more source
Montelukast sodium and doxofylline exhibit bronchodilator, anti-inflammatory, and mucoregulator activities. A stability-indicating RP-HPLC method was developed and validated as per ICH guidelines for their simultaneous estimation.
Kshatri N, Jha LL, Prajapati J, Jadav M
core +1 more source
The objective of present work was to prepare microspheres of montelukast sodium using a natural polymer- chitosan by spray drying method by using glutaraldehyde as a cross linking agent.
Rushi Panchal +4 more
doaj +1 more source
Reproxalap ‐ A Novel Treatment Option for Allergic Conjunctivitis – A Comprehensive Narrative Review
ABSTRACT Background and Aims Allergic conjunctivitis is a prevalent, immune‐mediated hypersensitivity disorder of the ocular surface affecting 10%–20% of the global population. Current therapeutic options, while effective to some extent, are often limited by side effects and inconsistent efficacy.
Sanila Mughal +7 more
wiley +1 more source
Encephalopathy: Cause, Pathogenesis, and Treatment
Various encephalopathies (sepsis‐associated, hepatic, hypoxic–ischemic, diabetic, uremic, toxic) have incompletely elucidated pathogenesis, which severely restricts targeted therapy development. Small molecule drugs show unique multitarget potential but face toxicity, poor blood–brain barrier penetration and unclear specificity.
Shimeng Lv +7 more
wiley +1 more source
Synthesis of Montelukast using dichloroimidazolidinedione (DCID) [PDF]
In this paper, a modified and scalable method for the preparation of montelukast (Singulair, a famous drug demonstrated for the chronic and prophylaxis therapy of asthma) is presented based on a new and useful method for performing substitution reactions.
Farzaneh Nasiri +3 more
doaj +1 more source
An oral bi layer sustained release (SR) strips of Sodium Montelukast SMLT , which is selective leukotriene antagonist , used for patients suffered from mid-night asthma , were prepared successfully ,using different polymers, like guar gum ...
Yehia I. Khalil
doaj +3 more sources
Effects of montelukast sodium on tendon healing: An experimental study
Montelukast sodium (MS) a selective leukotriene antagonist of the cysteinyl leukotriene receptor, has been used in the treatment of asthma and allergic rhinitis. In this study, we evaluated the effect of MS on the early inflammatory phase (histological) of nonsynovial tendon healing.Rats were divided randomly into two groups (n = 6 each). MS (Singulair)
Polat, Atilla +3 more
openaire +4 more sources
Electroanalytical Characterization of Montelukast Sodium and Its Voltammetric Determination in Pharmaceutical Dosage Form and Biological Fluids [PDF]
The electrochemical properties of montelukast sodium (MKST) at zinc oxide nanoparticles modified carbon paste electrode were investigated by cyclic voltammetry and square wave voltammetry.
Öztürk, Funda +3 more
core +1 more source

