Results 71 to 80 of about 617,785 (192)

The Effect of Montelukast Sodium on Serum Arginase Levels in Patients with Seasonal Allergic Rhinitis

open access: yes, 2011
Background Nitric oxide (NO) imbalance appears to be important in the pathogenesis of allergic rhinitis. NO is synthesized from L-arginine by NO synthase (NOS).
Husamettin Yasar   +9 more
core   +1 more source

Beneficial effects montelukast, cysteinyl-leukotriene receptor antagonist, on renal damage after unilateral ureteral obstruction in rats

open access: yesInternational Brazilian Journal of Urology, 2015
Introductıon Ureteral obstruction is a common pathology and caused kidney fibrosis and dysfunction at late period. In this present, we investigated the antifibrotic and antiinflammatory effects of montelukast which is cysteinyl leukotriene receptor ...
Alper Otunctemur   +8 more
doaj   +1 more source

DEVELOPMENT AND VALIDATION OF STABILITY-INDICATING RP-HPLC METHOD FOR SIMULTANEOUS DETERMINATION OF MONTELUKAST SODIUM AND DOXOFYLLINE IN TABLET FORMULATION

open access: yes
Montelukast sodium and doxofylline exhibit bronchodilator, anti-inflammatory, and mucoregulator activities. A stability-indicating RP-HPLC method was developed and validated as per ICH guidelines for their simultaneous estimation.
Kshatri N, Jha LL, Prajapati J, Jadav M
core   +1 more source

Formulation and evalution of montelukast sodium - chitosan based spray dried microspheres for pulmonary drug delivery

open access: yesJournal of Pharmacy and Bioallied Sciences, 2012
The objective of present work was to prepare microspheres of montelukast sodium using a natural polymer- chitosan by spray drying method by using glutaraldehyde as a cross linking agent.
Rushi Panchal   +4 more
doaj   +1 more source

Reproxalap ‐ A Novel Treatment Option for Allergic Conjunctivitis – A Comprehensive Narrative Review

open access: yesHealth Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background and Aims Allergic conjunctivitis is a prevalent, immune‐mediated hypersensitivity disorder of the ocular surface affecting 10%–20% of the global population. Current therapeutic options, while effective to some extent, are often limited by side effects and inconsistent efficacy.
Sanila Mughal   +7 more
wiley   +1 more source

Encephalopathy: Cause, Pathogenesis, and Treatment

open access: yesMedComm, Volume 7, Issue 6, June 2026.
Various encephalopathies (sepsis‐associated, hepatic, hypoxic–ischemic, diabetic, uremic, toxic) have incompletely elucidated pathogenesis, which severely restricts targeted therapy development. Small molecule drugs show unique multitarget potential but face toxicity, poor blood–brain barrier penetration and unclear specificity.
Shimeng Lv   +7 more
wiley   +1 more source

Synthesis of Montelukast using dichloroimidazolidinedione (DCID) [PDF]

open access: yesشیمی کاربردی روز
In this paper, a modified and scalable method for the preparation of montelukast (Singulair, a famous drug demonstrated for the chronic and prophylaxis therapy of asthma) is presented based on a new and useful method for performing substitution reactions.
Farzaneh Nasiri   +3 more
doaj   +1 more source

Preparation and Characterization of Montelukast Sodium ( SMLT ) as a Dual Sustained Release Buccal Strips

open access: yesIraqi Journal of Pharmaceutical Sciences, 2017
An oral bi layer  sustained release (SR) strips of Sodium  Montelukast SMLT , which is selective  leukotriene  antagonist  , used  for  patients  suffered from mid-night asthma , were prepared successfully ,using different polymers, like guar  gum ...
Yehia I. Khalil
doaj   +3 more sources

Effects of montelukast sodium on tendon healing: An experimental study

open access: yesIndian Journal of Orthopaedics, 2013
Montelukast sodium (MS) a selective leukotriene antagonist of the cysteinyl leukotriene receptor, has been used in the treatment of asthma and allergic rhinitis. In this study, we evaluated the effect of MS on the early inflammatory phase (histological) of nonsynovial tendon healing.Rats were divided randomly into two groups (n = 6 each). MS (Singulair)
Polat, Atilla   +3 more
openaire   +4 more sources

Electroanalytical Characterization of Montelukast Sodium and Its Voltammetric Determination in Pharmaceutical Dosage Form and Biological Fluids [PDF]

open access: yes, 2016
The electrochemical properties of montelukast sodium (MKST) at zinc oxide nanoparticles modified carbon paste electrode were investigated by cyclic voltammetry and square wave voltammetry.
Öztürk, Funda   +3 more
core   +1 more source

Home - About - Disclaimer - Privacy