Results 51 to 60 of about 617,785 (192)

Sodium Ions Affect GPR17 Conformational States and Functionality

open access: yesProteins: Structure, Function, and Bioinformatics, Volume 94, Issue 12, Page 1949-1964, December 2026.
ABSTRACT Sodium is an allosteric modulator of several class‐A GPCR regulating active versus inactive conformation state and may be a critical issue for the optimization of crystallization procedures. Herein, the role of Na+ in the regulation of GPR17 conformational states was studied through MD simulations of GPR17 wild‐type and mutated on two ...
Luca Palazzolo   +6 more
wiley   +1 more source

Formulation and In-vitro Evaluation of Chewable Tablets of Montelukast Sodium

open access: yes, 2015
The objective of the present study is to develop chewable tablets containing different pharmaceutical compositions with simple manufacturing procedures using different excipients.
Laxman Devkota   +2 more
core   +1 more source

A Current Evidence Review From the Italian Society of Pediatric Allergology and Immunology (SIAIP) on Practical Management of Allergic Rhinitis in Children and Adolescents

open access: yesClinical and Translational Allergy, Volume 16, Issue 11, November 2026.
ABSTRACT Background Allergic rhinitis (AR) is highly prevalent in children and adolescents and impairs quality of life, sleep, and school performance, while also worsening asthma control. The last EAACI position paper on pediatric AR was published in 2013.
Giorgio Ciprandi   +7 more
wiley   +1 more source

ZnO MODIFIED CARBON PASTE ELECTRODE WITH MONTELUKAST SODIUM VOLTAMMETRIC DETERMINATION [PDF]

open access: yes, 2019
Bu çalışmada, astım inhibitörü özelliğe sahip bir aktif madde olan Montelukast sodyumun elektrokimyasal davranışları; metanol - Britton-Robinson ortamında pH 2,3 de, çinko oksit na-nopartiküllü modifiye karbon pasta elektrot kullanılarak, dönüşümlü ...
Hatipoğlu, , Bernu
core   +1 more source

Development and Validation of Spectroscopic Method for Simultaneous Estimation of Acebrophylline and Montelukast Sodium in Combined Dosage Form

open access: yes, 2012
A novel combination of Acebrophylline and Montelukast Sodium is used in the treatment of chronic obstructive pulmonary disease (COPD) and bronchial asthma.
Jignesh Maniya *, Hasumati Raj, Hasmukh Vaghani, Manoj Mangukiya, Pradip Dudhat
core   +1 more source

pH‐Sensitive Alginate/Polyvinyl Alcohol/Chitosan Crosslinked With Tetraethyl Orthosilicate Polymeric Hybrid Hydrogel for Biomedical Application

open access: yesSPE Polymers, Volume 7, Issue 4, October 2026.
Fabrication steps of Alginate, PVA and chitosan hydrogel crosslinked with TEOS for azithromycin drug delivery application. ABSTRACT The main aim of this study was to develop a cost‐effective, pH‐sensitive Alginate (Alg), PVA, and chitosan (Cs) (Alg/PVA/Cs) hydrogel biocompatible polymer for controlled drug release of azithromycin.
Safia Hassan   +3 more
wiley   +1 more source

A Pilot Placebo‐Controlled Randomized Trial of Repeated High‐Dose Intravenous Magnesium Sulphate and High‐Dose Nebulized Budesonide for Severe Asthma in the Paediatric Emergency Department

open access: yesJournal of Paediatrics and Child Health, Volume 62, Issue 10, Page 1948-1958, October 2026.
ABSTRACT Objective Determine if high‐dose intravenous magnesium with/without nebulized budesonide for children with acute severe asthma is safe and reduces time to medical readiness for discharge compared to standard intravenous magnesium. Methods Either 2 doses of intravenous magnesium or 1 dose and placebo, each with/without high‐dose nebulized ...
Khalid Alansari   +5 more
wiley   +1 more source

A case report on the long‐term use of teduglutide in a pediatric patient with short bowel syndrome

open access: yesNutrition in Clinical Practice, Volume 41, Issue 4, Page 1253-1259, August 2026.
Abstract Short bowel syndrome (SBS) is the leading cause of intestinal failure, frequently necessitating long‐term parenteral nutrition (PN). Teduglutide (TED), a glucagon‐like peptide‐2 analog, has demonstrated efficacy in reducing PN dependence in both adults and children. However, long‐term data in pediatric populations remain limited.
Tsuyoshi Sakurai   +8 more
wiley   +1 more source

The International Guideline for the Definition, Classification, Diagnosis and Management of Urticaria

open access: yesAllergy, Volume 81, Issue 8, Page 2582-2632, August 2026.
ABSTRACT This update and revision of the international guideline for urticaria was developed in accordance with the methods recommended by Cochrane and the Grading of Recommendations Assessment, Development and Evaluation (GRADE) working group. It is an initiative of the Global Allergy and Asthma Excellence Network (GA2LEN) and its Urticaria and ...
Torsten Zuberbier   +221 more
wiley   +1 more source

Acute Liver Injury Following Outpatient Trimethoprim‐Sulfamethoxazole Use for Small Intestinal Bacterial Overgrowth: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT Drug‐induced liver injury (DILI) is a leading cause of acute liver failure in the United States and remains difficult to predict and diagnose. Trimethoprim‐sulfamethoxazole (TMP‐SMX) is widely prescribed and generally well tolerated, yet rare cases of severe idiosyncratic hepatotoxicity have been reported.
Kaylie Duit   +3 more
wiley   +1 more source

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