Effect of montelukast on platelet activating factor- and tachykinin induced mucus secretion in the rat [PDF]
, 2008 Background: Platelet activating factor and tachykinins (substance P, neurokinin A, neurokinin B) are important mediators contributing to increased airway secretion in the context of different types of respiratory diseases including acute and chronic ...
David A Groneberg +12 more
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Formulation development and optimization of orally disintegrating tablets of montelukast sodium by Design- Expert [PDF]
, 2018 Purpose: To prepare orally disintegrating tablets (ODT) of montelukast sodium using Design-Expert for improved patient compliance.Methods: Central composite design was selected to delineate and optimize the formulations.
Usman, Shahnaz +2 more
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In-Vitro Comparative Study of Levocetirizine Dihydrochloride and Montelukast Sodium Release Profiles in Xyzal M Suspension and Other Marketed Syrup Formulations [PDF]
, 2023 Objectives: In-vitro comparative analysis of the release profile of levocetirizine dihydrochloride and montelukast sodium in Xyzal M Suspension and three commercially available syrup formulations.
Veligandla, Krishna Chaitanya +7 more
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Formulation And Evaluation Of Medicated Soft Lozenges Of Montelukast Sodium [PDF]
, 2023 Lozenges are solid dosage forms that include one or more medications that are supposed to dissolve or disintegrate slowly in the mouth, or medicated candies that dissolve slowly in the mouth to lubricate and soothe sensitive throat tissue.
Dilnawaz Pathan +7 more
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Development of gastro retentive microbeads for sustained release of fexofenadine and montelukast
Journal of Contemporary Pharmacy, 2021 In allergic rhinitis, montelukast (leukotriene receptor antagonist) in combination with fexofenadine (antihistamine) provide improved and complimentary effects and reduce the allergic symptoms effectively.
Kainat Haleem +3 more
doaj +1 more source
Pharmaceutics, 2021 Montelukast is a weak acid drug characterized by its low solubility in the range of pH 1.2 to 4.5, which may lead to dissolution-limited absorption. The aim of this paper is to develop an in vivo predictive dissolution method for montelukast and to check
Mercedes Prieto-Escolar +9 more
doaj +1 more source
Fabrication of pure-drug microneedles for delivery of montelukast sodium
Drug Delivery and Translational Research, 2021 Dissolving microneedle (MN) patches are usually formulated with a blend of drug and excipients added for mechanical strength and drug stabilization. In this study, we developed MNs made of pure drug to maximize drug loading capacity. MN patches were fabricated for transdermal delivery of montelukast sodium (MS) which is used to treat asthma and ...
Erkan Azizoglu +2 more
openaire +4 more sources
Development of Newer Validated Analytical Methods for the Simultaneous Determination of Bilastine and Montelukast Sodium in Combined Dosage Form [PDF]
, 2021 UV spectrophotometric methods (simultaneous equation method and second order derivative spectroscopy) was developed for simultaneous analysis of bilastine and montelukast sodium in tablet formulation and validated as per ICH guidelines ...
Deepthi, S
core
, 2022 For the simultaneous determination of Montelukast sodium and Bilastine in combination utilising methanol as solvent, a new, simple, effective, explicit, definite, and sensitive UV spectrophotometric absorption correction method has been devised.
AdarshJha +3 more
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Exploring Montelukast Sodium and Calcium Chloride Interactions: A Comparative Study at Physiological and Gastric pH Levels [PDF]
Montelukast, a leukotriene receptor antagonist (LTRA) is used to prevent an asthmatic attack, shortness of breath and wheezing. As intravenous therapy, Calcium chloride (fused) is used to treat hypocalcemia.
Uddin, Md Sohorab +2 more
core +1 more source