Results 1 to 10 of about 301,098 (252)

The relationship between smartphone addiction and symptoms of depression, anxiety, and attention-deficit/hyperactivity in South Korean adolescents

open access: yesAnnals of General Psychiatry, 2019
Background Excessive smartphone use has been associated with numerous psychiatric disorders. This study aimed to investigate the prevalence of smartphone addiction and its association with depression, anxiety, and attention-deficit hyperactivity disorder
Seung-Gon Kim   +5 more
doaj   +1 more source

A randomized controlled trial of Internet-delivered guided and unguided cognitive behaviour therapy for treating depression and anxiety in UK university students: study protocol for the Nurture-U Internet CBT trial

open access: yesTrials
Background Tackling poor mental health in university students is a priority in higher education. Although major depressive disorder and generalized anxiety disorder are highly prevalent among university students and predict impaired university and later ...
E.R Watkins   +6 more
doaj   +1 more source

New Therapeutic Targets for Mood Disorders

open access: yesThe Scientific World Journal, 2010
Existing pharmacological treatments for bipolar disorder (BPD) and major depressive disorder (MDD) are often insufficient for many patients. Here we describe a number of targets/compounds that clinical and preclinical studies suggest could result in ...
Rodrigo Machado-Vieira   +8 more
doaj   +1 more source

Current and Emerging Therapies for the Management of Bipolar Disorders

open access: yesJournal of Central Nervous System Disease, 2011
Bipolar disorder is a complex condition to treat because agents that may be effective for a specific phase may not be effective for other phases, or may even worsen the overall course of the illness.
Rif S. El-Mallakh   +4 more
doaj   +1 more source

Discontinuing psychotropic drug treatment

open access: yesBJPsych Open, 2020
Interruption of ongoing treatment with benzodiazepines, antidepressants, antipsychotics and mood stabilisers including lithium can be followed by clinically significant withdrawal reactions within hours or days, as well as later increases in relapses or ...
Leonardo Tondo, Ross J. Baldessarini
doaj   +1 more source

A resource of induced pluripotent stem cell (iPSC) lines including clinical, genomic, and cellular data from genetically isolated families with mood and psychotic disorders

open access: yesTranslational Psychiatry, 2023
Genome-wide (GWAS) and copy number variant (CNV) association studies have reproducibly identified numerous risk alleles associated with bipolar disorder (BD), major depressive disorder (MDD), and schizophrenia (SCZ), but biological characterization of ...
Sevilla D. Detera-Wadleigh   +32 more
doaj   +1 more source

Research on the pathophysiology, treatment, and prevention of suicide: practical and ethical issues

open access: yesBMC Psychiatry, 2019
Background Despite decades of research, the rate of death from suicide is rising in the United States. Suicide is a complex and multifactorial phenomenon and, to date, no validated biomarkers that predict suicidal behavior have been identified.
Allison C. Nugent   +3 more
doaj   +1 more source

Roots and Shoots: A Pilot Parallel Randomised Controlled Trial Assessing the Feasibility and Acceptability of a Nature-Based Self-Help Intervention for Low Wellbeing

open access: yesBehavioral Sciences
The burden of depression is a public health concern, and traditional treatment approaches to mental health alone may be insufficient. The effects of contact with nature on wellbeing have been shown to reduce stress and improve mood, emotional wellbeing ...
Matthew Owens   +3 more
doaj   +1 more source

Evaluating Augmented Depression Therapy (ADepT): study protocol for a pilot randomised controlled trial

open access: yesPilot and Feasibility Studies, 2019
Background While existing psychological treatments for depression are effective for many, a significant proportion of depressed individuals do not respond to current approaches and few remain well over the long-term.
Barnaby D. Dunn   +16 more
doaj   +1 more source

Efficacy and Safety of Remote Ischemic Conditioning for Depression Insufficiently Responsive to Antidepressant: A Randomized Controlled Trial

open access: yesNeuropsychiatric Disease and Treatment
Jun Wang,1,* Yu Shuai,1,* Ming Ren,2,* Ningning Li,3 Xujuan Li,4 Wenfei Li,5 Binxun Jiang,4 Linlin Wang,4 Leping Huang,3 Xunming Ji,6,7 Zuowei Wang3,8 1Division of Mood Disorders, Shanghai Yangpu Mental Health Center, Shanghai ...
Wang J   +10 more
doaj  

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