Results 31 to 40 of about 301,098 (252)

An investigation of cannabis use for insomnia in depression and anxiety in a naturalistic sample

BMC Psychiatry, 2022
Background Little is known about cannabis use for insomnia in individuals with depression, anxiety, and comorbid depression and anxiety. To develop a better understanding of distinct profiles of cannabis use for insomnia management, a retrospective ...
Nirushi Kuhathasan, Luciano Minuzzi, James MacKillop, Benicio N. Frey   +3 more
doaj   +1 more source

Institutional Compassion in Student Transition to University: Findings from the Nurture-U Compassionate Campus Project

Education Sciences
Compassionate university practices can increase students’ sense of belonging and lead to higher wellbeing. This study presents qualitative data from a UK university collected as part of the Nurture-U Compassionate Campus project.
Jemima Dooley, Vanessa Forbes, Amelia Green, Pranati Misurya, Polly Card, Felicity Thomas, Ed Watkins, Louise Lawrence   +7 more
doaj   +1 more source

Parent Quality of Life at Two Years Following Their Child's Completion of Acute Lymphoblastic Leukemia Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Parents of children treated for acute lymphoblastic leukemia (ALL) often experience significant caregiver burden and disruption to their well‐being. While parent quality of life (QoL) during treatment is well characterized, little is known about outcomes during early survivorship.
Sara Dal Pra, Maria McCarthy, Michael Takagi, Cinzia De Luca   +3 more
wiley   +1 more source

NMDA receptor inhibition prevents intracellular sodium elevations in human olfactory neuroepithelial precursors derived from bipolar patients

Scientific Reports, 2022
Dysregulation of ion flux across membranes and glutamate-induced excitotoxicity appear to be important pathophysiologic abnormalities in bipolar illness. Understanding ion control and responses to ionic stress is important to decipher the pathogenesis of
Yonglin Gao, Aaron A. Mack, Carleigh Litteral, Nicholas A. Delamere, Rif S. El-Mallakh   +4 more
doaj   +1 more source

Erythromycin-induced psychotic decompensation in a patient affected by paranoid schizophrenic psychosis

Psychiatry and Clinical Psychopharmacology, 2021
The aim of this report is to present a case of acute psychotic decompensation in a patient suffering from paranoid schizophrenic psychosis with residual symptoms, treated with erythromycin for acute bronchitis.
Branislav Ostoja Šakić, Sinisa Svetozar Babović, Zoran Milan Gajić   +2 more
doaj   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

The Efficacy of Vortioxetine on Anhedonia in Patients With Major Depressive Disorder

Frontiers in Psychiatry, 2019
Background: Anhedonia is a common, persistent, and disabling phenomenon in treated adults with Major Depressive Disorder (MDD). Hitherto, relatively few antidepressant agents have been evaluated with respect to their effect on anhedonia in MDD.Methods ...
Bing Cao, Bing Cao, Caroline Park, Caroline Park, Mehala Subramaniapillai, Yena Lee, Yena Lee, Michelle Iacobucci, Rodrigo B. Mansur, Hannah Zuckerman, Lee Phan, Roger S. McIntyre, Roger S. McIntyre, Roger S. McIntyre, Roger S. McIntyre   +14 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A qualitative study exploring depressed participants’ experiences of receiving Augmented Depression Therapy (ADepT)

BMJ Open
Objectives The current study aimed to explore participants’ views on the acceptability, impact and mechanisms of change of Augmented Depression Therapy (ADepT), a novel wellbeing-focused and recovery-oriented psychological therapy for depression.Design A
Rebecca Watson, Kim A Wright, Nigel Reed, Barney Dunn, Emily Widnall, Kalliopi Demetriou, Laura Warbrick, Katie Marchant, Nicole Geschwind, Isabella Magner-Parsons, Rachel Barter   +10 more
doaj   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source