Antiallergic Effect of the Alpha-Cyclodextrin Moringin Complex in Rat Basophilic Leukaemia (RBL-2H3) Cell Line [PDF]
Advances in Pharmacological and Pharmaceutical SciencesAllergic diseases (ADs) are a major concern when it comes to public well-being. Moringa oleifera Lam is a tropical plant that is used in traditional medicine due to the presence of isothiocyanate.
Ebtisam Yousef A. Alnakeeb +8 more
doaj +5 more sources
The Moringin/α-CD Pretreatment Induces Neuroprotection in an In Vitro Model of Alzheimer’s Disease: A Transcriptomic Study [PDF]
Current Issues in Molecular Biology, 2021 Alzheimer’s disease (AD) is a progressive neurodegenerative disorder and represents the most common form of senile dementia. Autophagy and mitophagy are cellular processes that play a key role in the aggregation of β-amyloid (Aβ) and tau phosphorylation.
Serena Silvestro +8 more
doaj +10 more sources
Multi-Target Antibacterial Mechanism of Moringin From Moringa oleifera Seeds Against Listeria monocytogenes [PDF]
Frontiers in Microbiology, 2022 Moringin [4-(α-L-rhamnosyloxy) benzyl isothiocyanate] is an isothiocyanate from Moringa oleifera seeds. It is the bioactivated form of the glucosinolate precursor glucomoringin with various health benefits.
Yanlong Wen +22 more
doaj +4 more sources
Cardio- and neuroprotective effects by pretreatment of dietary moringin from Moringa oleifera seeds and α-CD/moringin formulation in a rat model of isoproterenol-induced myocardial infarction [PDF]
Journal of Nutritional ScienceThe aim of this study was to investigate the cardio- and neuroprotective effects of moringin (MG), a dietary isothiocyanate readily derived from Moringa oleifera seed, in a rat model of isoproterenol (ISP) induced myocardial infarction (MI).
Ahmad Faizal Abdull Razis +9 more
doaj +5 more sources
Histopathological and ultrastructural alterations reveal the hepatotoxicity of lead against Moringin: Sub-chronic-chemotherapeutic trial [PDF]
Open Veterinary JournalBackground: Several researchers in the past have described Lead acetate (LA), Pb, as a toxic heavy metal compound that can significantly affect the organs and the body systems, thereby influencing their functions.
Mohammed Abdulabbas Hasan
doaj +4 more sources
Moringin, A Stable Isothiocyanate from Moringa oleifera, Activates the Somatosensory and Pain Receptor TRPA1 Channel In Vitro [PDF]
Molecules, 2020 Moringa oleifera Lam. is a tropical plant widely used in traditional medicines and as a food supplement. It is characterized by the presence of glucosinolates and isothiocyanates; the stable isothiocyanate 4-[(α-l-rhamnosyloxy)benzyl]isothiocyanate (
Gigliola Borgonovo +7 more
doaj +6 more sources
Phytochemical Analyses, Antioxidant and Anticancer Activities of Ethanolic Leaf Extracts of Moringa oleifera Lam. Varieties [PDF]
Plants, 2021 Moringa oleifera Lam. (Moringaceae) is revered as s ‘miracle tree’ due to its remarkable nutritional, medicinal and industrial uses. In our study, a comparative analysis of the nutritional parameters (antioxidant activity, sugar content—TSS, total ...
Bilques Farooq +3 more
doaj +2 more sources
An insight into the neuroprotective and anti-neuroinflammatory effects and mechanisms of Moringa oleifera [PDF]
Frontiers in Pharmacology, 2023 Neurodegenerative diseases (NDs) are sporadic maladies that affect patients’ lives with progressive neurological disabilities and reduced quality of life.
Ummi Kalthum Azlan +10 more
doaj +2 more sources
Aqueous extracts of Moringa oleifera and Cinnamomum cassia as promising sources of antibiofilm compounds against mucoid and small colony variants of Pseudomonas aeruginosa and Staphylococcus aureus [PDF]
BiofilmBacterial biofilms formed by Staphylococcus aureus and Pseudomonas aeruginosa pose significant challenges in treating cystic fibrosis (CF) airway infections due to their resistance to antibiotics.
Eduarda Silva +5 more
doaj +2 more sources
The Potential of Glucosinolates and Their Hydrolysis Products as Inhibitors of Cytokine Storms [PDF]
MoleculesA cytokine storm is an intense inflammatory response characterized by the overproduction of proinflammatory cytokines, resulting in tissue damage, and organ dysfunction. Cytokines play a crucial role in various conditions, such as coronavirus disease, in
Kingsley Ochar +5 more
doaj +2 more sources