Cannabidiol effects in stem cells: A systematic review. [PDF]
CBD acts as a differentiator and protector of CSCs and exerts a significant antitumor effect against CSCs indicating a great potential as a new therapeutic strategy in regenerative medicine and oncology. Abstract Stem cells play a critical role in human tissue regeneration and repair.
Mesas C +6 more
europepmc +2 more sources
Isothiocyanate from Moringa oleifera seeds mitigates hydrogen peroxide-induced cytotoxicity and preserved morphological features of human neuronal cells. [PDF]
Reactive oxygen species are well known for induction of oxidative stress conditions through oxidation of vital biomarkers leading to cellular death via apoptosis and other process, thereby causing devastative effects on the host organs.
Mohammed Sani Jaafaru +4 more
doaj +1 more source
Rocket science: a review of phytochemical & health-related research in Eruca & Diplotaxis species [PDF]
Rocket species (Eruca spp. and Diplotaxis spp.) are becoming increasingly important leafy salad crops across the world. Numerous scientific research papers have been published in recent years surrounding the potential health benefits associated with ...
Agerbirk +82 more
core +1 more source
Moringin from Moringa Oleifera Seeds Inhibits Growth, Arrests Cell-Cycle, and Induces Apoptosis of SH-SY5Y Human Neuroblastoma Cells through the Modulation of NF-κB and Apoptotic Related Factors. [PDF]
In the last decades, glucosinolates (GLs), precursors of isothiocyanates (ITCs), have been studied mostly for their chemopreventive and chemotherapeutic properties. The aim of our research was to study the antiproliferative effect of 4-(α-L-rhamnopyranosyloxy) benzyl glucosinolate (glucomoringin; GMG) bioactivated by myrosinase enzyme to form the ...
Cirmi S +6 more
europepmc +5 more sources
Moringa isothiocyanate complexed with α-cyclodextrin: a new perspective in neuroblastoma treatment
Background Several lines of evidence suggest the consume of natural products for cancer prevention or treatment. In particular, isothiocyanates (ITCs) exerting anti-cancer properties, have received great interest as potential chemotherapeutic agents ...
Sabrina Giacoppo +4 more
doaj +1 more source
Cyclodextrins as Anti-inflammatory Agents: Basis, Drugs and Perspectives [PDF]
Inflammation is a biological response of the immune system to harmful stimuli. Importantly, inflammation is also a hallmark of several human diseases such as cancer or diabetes.
Caldera, Fabrizio +6 more
core +1 more source
Topical moringin cream relieves neuropathic pain by suppression of inflammatory pathway and voltage-gated ion channels in murine model of multiple sclerosis [PDF]
Background Neuropathic pain represents the major public health burden with a strong impact on quality life in multiple sclerosis patients. Although some advances have been obtained in the last years, the conventional therapies remain poorly effective. Thus, the discovery of innovative approaches to improve the outcomes for multiple sclerosis patients ...
Giacoppo, Sabrina +3 more
openaire +3 more sources
Characterization of GMG-ITC isolated from aerial parts of moringa oleifera tree [PDF]
Isothicyanate is a major bioactive compound in Moringa oleifera Lam. There are numerous literatures that report the therapeutic effects of isothiocyanates. It is for this reason that the local consumption of the plant is increasing. In the current study,
Abubakar, Rabiat Idrees +5 more
core +1 more source
Isolation and Modification of Plant Glucosinolates and their Role in the Prevention of Pathologies of the Central Nervous System [PDF]
The glucosinolate-myrosinase system is present in a large number of plants, mainly of the order Brassicales, including several common vegetables like broccoli, cabbage, kale, radish and rocket consumed worldwide.
De Nicola, Gina Rosalinda <1971>
core +1 more source
Redox modulation by plant polyphenols targeting vitagenes for chemoprevention and therapy: Relevance to novel anti-cancer interventions and mini-brain organoid technology [PDF]
The scientific community, recently, has focused notable attention on the chemopreventive and therapeutic effects of dietary polyphenols for human health.
Calabrese, Edward J +10 more
core +1 more source

