Results 121 to 130 of about 270,592 (355)
Changes in the Gene Expression of β1 and β2 Integrins Following Development of Tolerance to Analgesic Effect of Morphine in Rats [PDF]
Cell Journal, 2010 Objective: Considering the inhibitory effect of integrin-activity modulator (manganese) onthe development of morphine tolerance; in this study we have tried to assess the effectof chronic administration of both morphine and manganese on the expression ...
Jamal Ghorbi +2 more
doaj
Mitogen-Activated Protein Kinase Signaling Mediates Morphine Induced-Delayed Hyperalgesia
Frontiers in Neuroscience, 2019 The use of morphine, the standard opioid drug, is limited by its undesirable effects, such as tolerance, physical dependence, and hyperalgesia (increased pain sensitivity).
Bárbara Guimaraes de Freitas +6 more
doaj +1 more source
Litigation-Ending Sanctions: Alaska Courts’ Use of Rule 37 [PDF]
, 1985 Pain is a common symptom of a number of conditions including cancer and one of the most frequent reasons for seeking healthcare. Acute and chronic pain result in considerable discomfort with a detrimental impact on the quality of life.
Carroll, Robert
core +1 more source
Research progress on the mechanisms of pain empathy
Ibrain, EarlyView.This article is related to the graphical research progress of pain empathy, starting with the description of the pain matrix and mirror neurons. Based on the pain matrix and mirror neurons, pain empathy results from the combined action of brain regions such as the anterior cingulate cortex, insula, prefrontal cortex, and amygdala and regulatory ...
Shuangshuang Liu +5 more
wiley +1 more source
Unbearable Pain: India's Obligation to Ensure Palliative Care [PDF]
, 2009 This 102-page report found that many major cancer hospitals in India do not provide patients with morphine, despite the fact that more than 70 percent of their patients are incurable and likely to require pain treatment and palliative care.
core
Opioid modulation of GABA release in the rat inferior colliculus [PDF]
, 2004 Background: The inferior colliculus, which receives almost all ascending and descending auditory signals, plays a crucial role in the processing of auditory information.
Casalotti, SO +7 more
core +3 more sources
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Background Gynecological surgery is generally associated with a high risk of postoperative nausea and vomiting (PONV), for which a combination of antiemetic therapies is advised, but adherence to these protocols is often low. Given the current reality, a preferred 5‐HT3 receptor antagonist for preventing PONV as a result of gynecological ...
Hongxia Xu +7 more
wiley +1 more source
The effect of cannabinoid type 2 receptor agonist on morphine tolerance
IBRO Neuroscience ReportsPain highly impacts the quality of life of patients. Morphine is used for pain treatment; however, its side effects, especially morphine tolerance, limit its use in the clinic. The problem of morphine tolerance has plagued health workers and patients for
Di Cui, Yuanyuan Zhang, Mingyue Zhang
doaj
Basic and Clinical Neuroscience, 2020 Introduction: The GABAergic system of the brain plays a key role in morphine tolerance and sensitization. As isoniazid is a modulator of the GABAergic system, the present study aims to understand whether isoniazid can influence the induction of tolerance
Amir Abbas Barzegari, Kamran Shahabi
doaj
Applications of wavelet transform in classification of local field potential recorded from the rat brain in conditioned place preference paradigm [PDF]
arXivThis study investigates the multi-label classification of Local Field Potential (LFP) data from the hippocampus (HIP) and nucleus accumbens (NAc) in the rat brain, focusing on reward responses using the Conditioned Place Preference (CPP) paradigm. Rats were conditioned with saline, morphine, and food rewards, and LFP recordings were conducted from both
arxiv