Results 121 to 130 of about 339,726 (399)
Morphine is one of the most severely abused drugs in the world. Previous research on morphine addiction has focused on the central nervous system (CNS). Studies have shown that a two-way regulation of the brain and gut microbiota (GM), suggesting a link ...
Zhu Chen+8 more
doaj +1 more source
M3 muscarinic acetylcholine receptor facilitates the endocytosis of mu opioid receptor mediated by morphine independently of the formation of heteromeric complexes [PDF]
Morphine inefficiency to induce the internalization of mu opioid (MOP) receptors observed in numerous experimental models constitutes a paradigm of G-protein coupled receptor (GPCR) functional selectivity.
Alvarez-Curto, Elisa+2 more
core +1 more source
Morphine and alternative opioids in cancer pain: the EAPC recommendations
An expert working group of the European Association for Palliative Care has revised and updated its guidelines on the use of morphine in the management of cancer pain.
G. Hanks+14 more
semanticscholar +1 more source
Scenarios of drug exposure and administration as well as detection assays for drugs and methods of sports doping published between 2023 and 2024 are critically reviewed and evaluated in context with the Prohibited List 2024 as established by the World Anti‐Doping Agency.
Mario Thevis+2 more
wiley +1 more source
n ...
von Gerichten, E., Schrötter, Hugo
openaire +2 more sources
Amniotic-Fluid Ingestion Enhances the Central\ud Analgesic Effect of Morphine [PDF]
Amniotic fluid and placenta contain a substance (POEF) that when ingested enhances opioid-mediated analgesia produced by several agents (morphine injection, vaginal/cervical stimulation, late pregnancy, footshock), but not that produced by aspirin ...
DiPirro, Jean M.+2 more
core
Development and validation of an extraction method based on dispersive liquid–liquid microextraction for the analysis by GC–MS of propofol in three different biological samples (blood, urine, and hair). The proposed method is very simple and rapid.
Sara Odoardi+4 more
wiley +1 more source
Failure of Intravenous Morphine to Serve as an Effective Instrumental Reinforcer in Dopamine D2 Receptor Knock-Out Mice [PDF]
The rewarding effects of opiates are thought to be mediated through dopaminergic mechanisms in the ventral tegmental area, dopamine-independent mechanisms in the nucleus accumbens, or both. The purpose of the present study was to explore the contribution
Elmer, Greg I.+5 more
core +1 more source
Non-opioid analgesics, paracetamol, non-steroidal anti-inflammatory drugs (NSAIDs), or cyclo-oxygenase 2 (COX-2) inhibitors are often given along with morphine as part of multimodal analgesia after major surgery.
E. Maund+5 more
semanticscholar +1 more source
Among 23,900 urine and oral fluid drug tests from Swedish workplaces, 4.6% tested positive for controlled substances. Cannabis, amphetamine, cocaine and benzodiazepines were most common. Many samples containing opiates, amphetamine or benzodiazepines were MRO verified as being due to medical prescriptions, while cannabis or cocaine were almost entirely
Anders Helander, Fredrik Sparring
wiley +1 more source