Results 61 to 70 of about 303,149 (361)
Effect of intrauterine morphine sulfate exposure on cerebellar histomorphological changes in neonatal mice [PDF]
Neurotoxic effects of morphine sulfate in adult cerebellar cortex and neonatal cerebral cortex have been studied in animal models. This study was done to determine the neurotoxic effects of prenatal morphine exposure on the histo morphological changes of
Ghafari, S. +2 more
core
Prescribing competence: The pros and cons of different methods for assessment
Evaluating a medical graduate’s competence in rational prescribing is challenging. With the aim to guide and inspire teachers, this narrative review explores different methods that can be used to assess prescribing competence. Each method has its own advantages and disadvantages, and thus a mix of different assessment methods is needed throughout the ...
David J. Brinkman +3 more
wiley +1 more source
Morphine Analgesia Pre-PPCI Is Associated with Prothrombotic State, Reduced Spontaneous Reperfusion and Greater Infarct Size [PDF]
Schattauer GmbH Stuttgart.The emergency management of ST-elevation myocardial infarction (STEMI) involves treatment with dual-antiplatelet therapy (DAPT) and primary percutaneous coronary intervention (PPCI). Pain is generally treated with opiates, which
Farag, Mohamed +5 more
core +2 more sources
Aims Analgesic medicines are an important component of pain management, with different medicines carrying different risks and benefits. The aim of this study was to examine trends in analgesic prescribing in Ireland and England between 2014 and 2022. Methods Monthly data on medicines prescribed and dispensed in primary care were used. For Ireland, data
Molly Mattsson +8 more
wiley +1 more source
The most important side effect of addictive drugs is their interaction with nervous system so that soon after taking the drug, the neurons̉ connections in nervous system are addicted to receiving the drugs frequently. The aim of this study was the effect
Eebrahim Hosseini +4 more
doaj
Female rat hippocampal cell density after conditioned place preference [PDF]
The hippocampus is important for learning tasks, such as conditioned place preference (CPP), which is widely used as a model for studying the reinforcing effects of drugs with dependence liability.
Babakordi, F. +3 more
core
Pregabalin effect on acute and chronic pain after cardiac surgery [PDF]
Introduction. Pain after cardiac surgery affects long-term patient wellness. This study investigated the effect of preoperative pregabalin on acute and chronic pain after elective cardiac surgery with median sternotomy. Methods.
Arnaoutoglou, Elena +6 more
core +3 more sources
Aims Monitoring opioid prescribing across different healthcare systems is essential to understanding population‐level exposure and informing global health policies. This study examined opioid utilization in Scandinavian countries between 2010 and 2023 using multiple complementary metrics, addressing the limitations of single‐metric comparisons ...
Gabriela Rolová +6 more
wiley +1 more source
Aims The aim of this study was to describe prescription use of acetaminophen, a widely used analgesic and antipyretic generally considered safe during pregnancy, among pregnant women from 2000 to 2023 in Denmark with special attention towards variations following the change in over‐the‐counter (OTC) availability in 2013.
Erika B. Gram +4 more
wiley +1 more source
Background: The aim of this study was to investigate the possible role of Protein Kinase Cᵧ (PKCᵧ) in morphine tolerance and induced hyperalgesia following repeated morphine administration in male rats. Material and Methods: Rats were divided into
Kobra Ghasemloo +3 more
doaj

