Results 61 to 70 of about 270,592 (355)

The use of international classification of diseases codes to identify hospital admissions linked with adverse drug events: Validation study

British Journal of Clinical Pharmacology, EarlyView.
Aims Several methods exist to identify hospital admissions related to adverse drug events (ADEs). Clinical adjudication by healthcare professionals is the gold standard but is labour‐intensive. Spontaneous reporting and routinely collected healthcare data using a set of International Classification of Diseases (ICD) codes often underestimate the ...
Zuzana Juhásová, Fatma Karapinar‐Çarkit, Daniala L. Weir   +2 more
wiley   +1 more source

DNMT3a in the hippocampal CA1 is crucial in the acquisition of morphine self‐administration in rats [PDF]

, 2019
Drug‐reinforced excessive operant responding is one fundamental feature of long-lasting addiction‐like behaviors and relapse in animals. However, the transcriptional regulatory mechanisms responsible for the persistent drug‐specific (not natural rewards)
Duan, Ying, Jiang, Feng-Ze, Jin, Su-Bo, Li, Ming, Liang, Jing, Shen, Fang, Sui, Nan, Zhang, Jian-Jun, Zheng, Wei   +8 more
core   +1 more source

A novel behavioral fish model of nociception for testing analgesics [PDF]

, 2011
Pain is a major symptom in many medical conditions, and often interferes significantly with a person's quality of life. Although a priority topic in medical research for many years, there are still few analgesic drugs approved for clinical use.
Ana D. Correia, Ashley, Barrallo, Bowman, Braithwaite, Breivik, Breivik, Brunner, Chervova, Chervova, Chervova, Cunha, Dunlop, E. Don Stevens, Ehrensing, Friend, Gonzalez-Nunez, Herrero-Turrion, Le Bars, Mansour, Martin Scholze, Matthes, Newby, Newby, Newby, Nordgreen, Nordgreen, Reilly, Ribeiro, Ribeiro, Sanchez-Simon, Sneddon, Sneddon, Sneddon, Sneddon, Sneddon, Stevens, Stevens, Sérgio R. Cunha, Tukey, Wheeler-Aceto, Zon   +41 more
core   +3 more sources

Nonconventional Techniques in Plant Alkaloid Extraction: A Decade of Progress (2014–2023)

Chemistry &Biodiversity, EarlyView.
This figure seeks to represent the evolution of the different unconventional approaches that were adopted for the extraction of plant‐derived alkaloids during the decade from 2014 to 2023. ABSTRACT Plant metabolism encompasses primary and secondary pathways, with secondary metabolism yielding diverse natural products crucial for plant adaptation and ...
Victor Menezes Sipoloni, Milena Costa Bassicheto, Maria Vitória de Oliveira, Ana Beatriz dos Santos de Souza, Gabriella Melo Alves, Thiago André Moura Veiga   +5 more
wiley   +1 more source

The Effect of Memory Reinforcement by Cholinergic Agonist and Music on Creating Morphine Dependency in Mice Using Conditioned Place Preference (CPP) Method

فصلنامه دانشگاه علوم پزشکی جهرم, 2013
The most important side effect of addictive drugs is their interaction with nervous system so that soon after taking the drug, the neurons̉ connections in nervous system are addicted to receiving the drugs frequently. The aim of this study was the effect
Eebrahim Hosseini, Mokhtar Mokhtari, Akbar Vahdati, Neamat Razmi, Farnaz Tavakoli   +4 more
doaj  

Acute and chronic effects of morphine on Low-Mg2+ ACSF-induced epileptiform activity during infancy in mice hippocampal slices

Research in Pharmaceutical Sciences, 2019
Interaction of morphine and seizure is complex. Mouse brain hippocampal slices were used to estimate how acute and chronic morphine treatment alters the low-magnesium artificial cerebrospinal fluid (LM-ACSF)-induced seizure activity.
Yousef Panahi, Ehsan Saboory, Shiva Roshan-Milani, Leila Drafshpoor, Yousef Rasmi, Ali Rassouli, Goudarz Sadeghi-Hashjin   +6 more
doaj   +1 more source

The Effect of Memantine on the Expression of Dopamine Receptors in the Striatum of Male Rats With Morphine Addiction [PDF]

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2023
Background and Objectives: Studies have indicated that the chronic use of morphine can result in physical and psychological dependence. Morphine dependence is associated with several cellular and molecular alterations in the mesocorticolimbic system, and
Sahar Khalili Samani, Solmaz Khalifeh, Mehdi Vahiddastjerdi, Mandana Hassanzad, Afshin Kheradmand, Farzaneh Nazari Serenjeh   +5 more
doaj  

Influence of Nitric Oxide in the Central Amygdala on the Acquisition and Expression of Morphine-Induced Place Preference in Morphine Sensitized Rats

Basic and Clinical Neuroscience, 2011
Effects of intra-central amygdala administration of L-arginine, a nitric oxide precursor, and NG-nitro-L-arginine methyl-ester (L NAME), a nitric oxide synthase inhibitor, on the morphine-induced sensitization and also on the expression of morphine ...
Hedayat Sahraei, Mohammad-Reza Zarrindast, Jamal Shams, Akram Eidi, Hassan Ghoshooni, Homeira Zardooz, Sara Sadeghi-Gharachehdaghi, Sara Bijani   +7 more
doaj   +2 more sources

Ethnomedicinal Uses, Phytochemistry, Pharmacological Activities, and Toxicology of the Subfamily Gomphrenoideae (Amaranthaceae): A Comprehensive Review

Chemistry &Biodiversity, EarlyView.
ABSTRACT The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its ...
Dayanna Isabel Araque Gelves, Giulia Cristina de Andreoli Souza, Alvaro Jose Hernandez Tasco, Marcos José Salvador   +3 more
wiley   +1 more source

PREVALENSI KEJADIAN PONV PADA PEMBERIAN MORFIN SEBAGAI ANALGETIK PASCA OPERASI PENDERITA TUMOR PAYUDARA DENGAN ANESTESI UMUM DI RSUP DR. KARIADI SEMARANG [PDF]

, 2015
Background Morphine is the most abundant analgesic which commonly used for post mastectomy’s pain reliever. Altough, it is potentially cause the adverse effect such as nausea and vomiting.
Dwi Jatmiko, Heru, Qudsi, Alfiani Sofia
core