Results 61 to 70 of about 339,726 (399)
Virtual reality mobility for burn patients (VR‐MOBILE): A within‐subject‐controlled trial protocol
Paediatric and Neonatal Pain, Volume 4, Issue 4, Page 192-198, December 2022., 2022 Abstract In the acute phase, burn patients undergo several painful procedures. Pediatric burn care procedures conducted in hydrotherapy have been known to generate severe pain intensity and moderate to high levels of anxiety. Hydrotherapy treatments are done with the use of opioids and benzodiazepines for pain and anxiety.
Sylvie Le May +8 more
wiley +1 more source
Automatic prediction of mortality in patients with mental illness using electronic health records [PDF]
arXiv, 2023 Mental disorders impact the lives of millions of people globally, not only impeding their day-to-day lives but also markedly reducing life expectancy. This paper addresses the persistent challenge of predicting mortality in patients with mental diagnoses using predictive machine-learning models with electronic health records (EHR).
arxiv
Morphine Metabolism in Human Skin Microsomes [PDF]
, 2012 For patients with severe skin wounds, topically applied morphine is an option to induce efficient analgesia due to the presence of opioid receptors in the skin.
Heilmann, S. +2 more
core +2 more sources
Altered morphine glucuronide and bile acid disposition in patients with nonalcoholic steatohepatitis
Clinical pharmacology and therapy, 2015 The functional impact of altered drug transport protein expression on the systemic pharmacokinetics of morphine, hepatically derived morphine glucuronide (morphine‐3‐ and morphine‐6‐glucuronide), and fasting bile acids was evaluated in patients with ...
BC Ferslew +8 more
semanticscholar +1 more source
Same storm, different boat: The global impact of COVID‐19 on palliative care
Psycho-Oncology, Volume 32, Issue 1, Page 148-154, January 2023., 2023 Abstract Objective The COVID‐19 pandemic has had a complex and profound impact on the provision of palliative care globally. To support learning from palliative care providers and researchers worldwide, the Education Subcommittee of International Psycho‐Oncology Society (IPOS) Palliative Care Special Interest Group developed a webinar with ...
Kelcie D. Willis +7 more
wiley +1 more source
Reduction of prefrontal purinergic signaling is necessary for the analgesic effect of morphine
iScience, 2021 Summary: Morphine is commonly used to relieve moderate to severe pain, but repeated doses cause opioid tolerance. Here, we used ATP sensor and fiber photometry to detect prefrontal ATP level.
Yeting Zeng +7 more
doaj
Amniotic-Fluid Ingestion Enhances\ud Morphine Analgesia During Morphine\ud Tolerance and Withdrawal in Rats [PDF]
, 1991 Ingestion of placenta and amniotic fluid has been shown to enhance opioid-mediated analgesia in rats produced by morphine injection. footshock, vaginal/cervical stimulation, and during late pregnancy.
Doerr, Jean C., Kristal, Dr. Mark B.
core
Prefrontal FGF1 Signaling is Required for Accumbal Deep Brain Stimulation Treatment of Addiction
Advanced Science, EarlyView.This research delineates that a cortical‐accumbal pathway and local FGF1 signaling in the medial prefrontal cortex are critical for NAc‐DBS to be effective in altering morphine CPP. These findings demonstrate a top‐down motif to regulate the therapeutic effects of subcortical DBS on addiction and support the potential for addiction treatments involving
Wan‐Kun Gong +11 more
wiley +1 more source
Rapid Communications in Mass Spectrometry, EarlyView., 2022 Rationale Carfentanil, an opioid 10K times more potent than morphine, has no licit clinical use. A powerful CNS depressant, it has been identified increasingly as the cause of overdose death in the United States. Because it is highly lipophilic, the law enforcement and medical communities have been concerned that responding personnel could be ...
Jonathan M. Oyler +2 more
wiley +1 more source
Scientific Reports, 2015 Although morphine is the standard opioid analgesic for pain control and has been widely used, certain drug-induced adverse effects have been reported as intolerable and need to be addressed.
Zheng Zeng +7 more
semanticscholar +1 more source