Results 71 to 80 of about 303,149 (361)
Behavioral and Brain Functions, 2012 Background Repeated morphine exposure can induce behavioral sensitization. There are evidences have shown that central gamma-aminobutyric acid (GABA) system is involved in morphine dependence.
Fu Zhenyu +4 more
doaj +1 more source
Opiate Drug Seeking and Addiction: The Influence of Sucrose Consumption on the Acquisition and Expression of Morphine-induced Conditioned Place Preferences (CPP) [PDF]
, 2019 Sucrose intake may lead to changes in brain and behavior similar to the effects of abused drugs. For example, sucrose may agonize endogenous opiate systems and modulate opiate-seeking behavior.
Bakner, Lee +3 more
core +1 more source
Psychoactive prescription drug use and misuse in patients on opioid agonist treatment
British Journal of Clinical Pharmacology, EarlyView.Aims To identify the patterns and trends in prescription drug use and misuse in patients on opioid agonist treatment. Methods We used data from the OPPIDUM programme, which collects data from patients attending substance abuse treatment facilities. Data collected include use of psychoactive prescription drugs in the past week.
Thomas Soeiro +5 more
wiley +1 more source
Journal of Research in Medical Sciences, 2004 Background: There is growing evidence indicating that neuronal calcium channels play an important role in the mechanism of Morphine dependence. Objective: To investigate the acute and long-term effects of Verapamil in Morphine dependent mice.
M Rabbani, A Jafarian, M Sobhanian
doaj
Litigation-Ending Sanctions: Alaska Courts’ Use of Rule 37 [PDF]
, 1985 Pain is a common symptom of a number of conditions including cancer and one of the most frequent reasons for seeking healthcare. Acute and chronic pain result in considerable discomfort with a detrimental impact on the quality of life.
Carroll, Robert
core +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims Pain is common in patients with Crohn's disease (CD) and ulcerative colitis (UC), and a substantial proportion develop chronic opioid use (COU). We examined the persistence of COU over time and identified factors predicting persistent use. Methods This nationwide Danish cohort study included patients with an initial period of COU (definition: ≥3 ...
Bente Mertz Nørgård +6 more
wiley +1 more source
Unbearable Pain: India's Obligation to Ensure Palliative Care [PDF]
, 2009 This 102-page report found that many major cancer hospitals in India do not provide patients with morphine, despite the fact that more than 70 percent of their patients are incurable and likely to require pain treatment and palliative care.
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Antinociceptive and Anti‐inflammatory Effect of Nicandrin B Isolated From Datura ferox in Zebrafish
Chemistry &Biodiversity, EarlyView.ABSTRACT Nicandrin B (Nic B), a withanolide isolated from Datura ferox leaves, was investigated for its antinociceptive and anti‐inflammatory effects in adult zebrafish (Danio rerio). Animals treated with Nic B (4, 20, and 40 mg/kg) showed no toxicity and maintained normal locomotor activity.
Jéssica Bezerra Maciel +15 more
wiley +1 more source
Journal of Pharmacy and Pharmacology, 1957 Abstract A series of compounds which antagonise the depressant activity of morphine in dogs is described. The most active compounds are the previously described 2:4-diamino-5-phenylthiazole and tetrahydro-5-aminoacridine. A mixture of both substances is more active than either alone.
F H, SHAW, S, GERSHON, G A, BENTLEY
openaire +2 more sources
Dopamine D4 receptor counteracts morphine-induced changes in M opioid receptor signaling in the striosomes of the rat caudate putamen. [PDF]
, 2015 Morphine is one of the most potent analgesic drugs used to relieve moderate to severe pain. After long-term use of morphine, neuroadaptive changes in the brain promotes tolerance, which result in a reduced sensitivity to most of its effects with ...
De-la-Calle-Martin, Adelaida +6 more
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