Results 101 to 110 of about 54,036 (205)

A Conantokin Peptide Con-T[M8Q] Inhibits Morphine Dependence with High Potency and Low Side Effects. [PDF]

Mar Drugs, 2021
Liu Z, Yu Z, Yu S, Zhu C, Dong M, Mao W, Hu J, Prorok M, Su R, Dai Q.   +9 more
europepmc   +1 more source

The epigenetic signatures of opioid addiction and physical dependence are prevented by D-cysteine ethyl ester and betaine

Frontiers in Pharmacology
We have reported that D,L-thiol esters, including D-cysteine ethyl ester (D-CYSee), are effective at overcoming opioid-induced respiratory depression (OIRD) in rats.
Jennifer McDonough, Naveen K. Singhal, Paulina M. Getsy, Katherine Knies, Zackery T. Knauss, Devin Mueller, James N. Bates, Derek S. Damron, Stephen J. Lewis, Stephen J. Lewis, Stephen J. Lewis   +10 more
doaj   +1 more source

Mitigating morphine dependence and withdrawal: The role of venlafaxine and calcium channel blockers in mitochondrial damage and oxidative stress in the brain

Brain Research Bulletin
Background: The reasons for morphine dependence and withdrawal symptoms are oxidative stress and dysfunction of cell mitochondria in the brain. Venlafaxine, a serotonin-norepinephrine reuptake inhibitor (SNRI), mitigates oxidative stress, while calcium ...
Radman Amiri, Faezeh Fallah, Behnam Ghorbanzadeh, Ali Akbar Oroojan, Mohammad Amin Behmanesh, Soheila Alboghobeish   +5 more
doaj   +1 more source

Ethanolic extract of anise (Pimpinella anisum L.) attenuates morphine physical dependence in mice [PDF]

, 2017
Introduction: Previous studies revealed that anise (Pimpinella anisum L.) has several pharmacological effects including analgesic, antidepressant, anxiolytic, anti-inflammatory and antispasmodic activities.
Abbasi-Maleki, Saeid., Shirzadi, Dara., Zanbouri, Ali.   +2 more
core   +1 more source

Effect of 8-Week Aerobic, Strength and Concurrent Training on Circulating Apelin in Morphine-Dependent Rats

Medical Laboratory Journal, 2017
Background and Objectives: Previous studies have shown that morphine dependence leads to myocardial dysfunction. In addition, apelin plays a protective role in cardiac function. The purpose of this study was to evaluate effects of morphine dependence and
Ebrahim Zarrinkalam, Ali Heidarianpour
doaj  

Buprenorphine in Neonatal Abstinence Syndrome. [PDF]

, 2018
Infants exposed in utero to opioids will demonstrate a withdrawal syndrome known as neonatal abstinence syndrome (NAS). Buprenorphine is a long-acting opioid with therapeutic use in medication-assisted treatment of opioid dependency in adults and ...
Kraft, Walter K.
core   +1 more source

The role of morphine dependence on the level of anxiety in Rat

مجله دانشگاه علوم پزشکی گرگان, 2008
Background & Objective: The effects of acute and chronic exposures to opiate drugs on anxiety process are controversial. Acute morphine injection showed the beneficial effects on anxiety.
Hossein Miladi Gorji (MSc), Ali Rashidy-Pour (PhD), Yaghoob Fathollahi (PhD), Abbas Ali Vafahi (PhD), Abbas Ali Taherian (MD)   +4 more
doaj  

Systemic and Intra-Habenular Activation of the Orphan G Protein-Coupled Receptor GPR139 Decreases Compulsive-Like Alcohol Drinking and Hyperalgesia in Alcohol-Dependent Rats. [PDF]

, 2018
GPR139 is an orphan G protein-coupled receptor (GPCR) that is expressed mainly in the brain, with the highest expression in the medial habenula. The modulation of GPR139 receptor function has been hypothesized to be beneficial in the treatment of some ...
Conlisk, Dana, de Guglielmo, Giordano, George, Olivier, Kallupi, Marsida, Kimbrough, Adam, Kononoff, Jenni   +5 more
core  

Clinical and Imaging Study of Repetitive Transcranial Magnetic Stimulation in the Treatment of Morphine Dependence Through mGluR5/TDP43/NR2B Pathway.

J Healthc Eng, 2021
Li X, Li C, Yu J, Ji Q, Wang W, Peng Y, Zhu X, Liu J.   +7 more
europepmc   +1 more source

Gut microbiota dysbiosis and hepatic inflammation in morphine dependence and withdrawal: insights from a rat model. [PDF]

BMC Gastroenterol
Yousefi S, Sadeghi-Adl M, Tarashi S, Siadat SD.   +3 more
europepmc   +1 more source